Results 91 to 100 of about 67,505 (283)

Ivermectin has New Application in Inhibiting Colorectal Cancer Cell Growth

open access: yesFrontiers in Pharmacology, 2021
Colorectal cancer (CRC) is the third most common cancer worldwide and still lacks effective therapy. Ivermectin, an antiparasitic drug, has been shown to possess anti-inflammation, anti-virus, and antitumor properties. However, whether ivermectin affects
Shican Zhou   +9 more
doaj   +1 more source

Presence of the ABCB1 (MDR1) deletion mutation causing ivermectin hypersensitivity in certain dog breeds in Belgium [PDF]

open access: yes, 2009
Hypersensitivity to ivermectin and certain other drugs in Collies and related breeds is caused by a 4-base pair deletion mutation in the ABCB1 gene, better known as the MDR1 gene, encoding P-glycoprotein.
Daminet, Sylvie   +9 more
core   +2 more sources

Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta [PDF]

open access: yes, 2017
Preventive chemotherapy has long been practiced against nematode parasites of livestock, leading to widespread drug resistance, and is increasingly being adopted for eradication of human parasitic nematodes even though it is similarly likely to lead to ...
Bisset, Stewart A   +6 more
core   +4 more sources

Physiological and behavioural effects of continuous remifentanil‐xylazine administration in donkeys

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Remifentanil and xylazine are used as continuous infusions to facilitate standing surgery in horses. Their use for this purpose has not been reported in donkeys. Objectives To evaluate the behavioural, sedative, and cardiorespiratory effects of continuous intravenous infusion of remifentanil and xylazine in donkeys. Study Design Non‐
Kássia Fernanda Araújo Damasceno   +6 more
wiley   +1 more source

Early-life exposure to Ivermectin alters long-term growth and disease susceptibility.

open access: yesPLoS ONE, 2021
Ivermectin is a broad-spectrum antiparasitic medicine, which is often used as a treatment for parasites or as a prophylaxis. While studies have looked at the long-term effects of Ivermectin on helminths, studies have not considered the long-term impacts ...
Taegan A McMahon   +2 more
doaj   +1 more source

Co-infection with Onchocerca volvulus and Loa loa microfilariae in central Cameroon: are these two species interacting? [PDF]

open access: yes, 2006
Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L.
Basáñez, M-G   +6 more
core   +1 more source

Ivermectin as a potential COVID-19 treatment from the pharmacokinetic point of view: antiviral levels are not likely attainable with known dosing regimens

open access: yes, 2020
The broad-spectrum antiparasitic agent ivermectin has been very recently found to inhibit SARS-CoV-2 in vitro and proposed as a candidate for drug repurposing in COVID-19. In the present report the in vitro antiviral activity end-points are analyzed from
G. Momekov, D. Momekova
semanticscholar   +1 more source

Ivermectin reduces in vivo coronavirus infection in a mouse experimental model

open access: yesScientific Reports, 2021
The objective of this study was to test the effectiveness of ivermectin for the treatment of mouse hepatitis virus (MHV), a type 2 family RNA coronavirus similar to SARS-CoV-2.
A. Arévalo   +11 more
semanticscholar   +1 more source

Effect of land use change on Melolonthidae (Coleoptera: Scarabaeoidea) beetle communities in the deforestation arc of the Brazilian Amazon

open access: yesInsect Conservation and Diversity, EarlyView.
Habitat transformation in Amazon due to agriculture expansion impairs Melolonthidae diversity. Assemblage response towards habitat transformation are group‐dependent. Although highly disturbed, Amazon arc of deforestation region dwells sensitive insect assemblages. Abstract Although the Amazon provides crucial goods and ecosystem services for humanity,
Kleyton Rezende Ferreira   +4 more
wiley   +1 more source

Uncertainty surrounding projections of the long-term impact of ivermectin treatment on human onchocerciasis.

open access: yesPLoS Neglected Tropical Diseases, 2013
BackgroundRecent studies in Mali, Nigeria, and Senegal have indicated that annual (or biannual) ivermectin distribution may lead to local elimination of human onchocerciasis in certain African foci.
Hugo C Turner   +5 more
doaj   +1 more source

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