Results 11 to 20 of about 50,912 (262)

Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug [PDF]

open access: yes, 2013
BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Adelfio, R.   +5 more
core   +13 more sources

Permethrin and Ivermectin for Scabies [PDF]

open access: yesNew England Journal of Medicine, 2010
In a remote aboriginal community in tropical northern Australia, a mother comes to the health center with her 4-year-old son, who has multiple sores on the skin of his arms and legs. He is treated with a single dose of intramuscular penicillin G benzathine and with the application of topical 5% permethrin cream over his whole body.
Currie, Bart J., McCarthy, James S.
openaire   +4 more sources

Effects of larval exposure to sublethal doses of ivermectin on adult fitness and susceptibility to ivermectin in Anopheles gambiae s.s.

open access: yesParasites & Vectors, 2023
Background The effects of ivermectin (endectocide) on mosquito survival make it a potential new malaria vector control tool. The drug can be administered to mosquito disease vectors through blood hosts that include humans and livestock. Its increased use
Caroline Kiuru   +6 more
doaj   +1 more source

Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results. [PDF]

open access: yes, 2005
In order to identify the factors influencing compliance with mass ivermectin treatment for onchocerciasis control, a cross-sectional study was carried out in Bushenyi District, Uganda. Data were collected by interviewing 839 individuals who were randomly
Ndyomugyenyi, Richard   +2 more
core   +1 more source

Chromatographic Quantification of Ivermectin and Pranziquantel in the Tablets Using Stability Indicating RP-HPLC Method [PDF]

open access: yesPharmaceutical Sciences, 2019
Background: A new stability indicating RP-HPLC based assay method was developed to quantify ivermectin and praziquantel simultaneously and applied effectively to tablets.
Naga Venkata Suresh Kumar Devaka   +1 more
doaj   +1 more source

Effect of Ivermectin Treatment on the Frequency of Seizures in Persons with Epilepsy Infected with Onchocerca volvulus

open access: yesPathogens, 2020
A clinical trial performed in the Democratic Republic of Congo (DRC), among persons with epilepsy (PWE) infected with Onchocerca volvulus treated with anti-seizure medication suggested that ivermectin reduces the seizure frequency. We assessed the effect
Alfred Dusabimana   +9 more
doaj   +1 more source

Ivermectin and malaria control [PDF]

open access: yesMalaria Journal, 2017
As the world begins to realize the very real prospect of eliminating malaria as a public health problem globally, the scientific community is acutely aware that novel and innovative new tools will be required if that lofty goal is to be accomplished.
Satoshi Ōmura, Andy Crump
openaire   +4 more sources

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness [PDF]

open access: yes, 2017
Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca ...
Basáñez, Maria-Gloria   +12 more
core   +2 more sources

Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways

open access: yesPharmacology Research & Perspectives, 2022
Advanced hepatocellular carcinoma (HCC) results in generally poor clinical outcomes and necessitates better therapeutic strategies. Ivermectin, which is an existing anti‐parasitic drug, has been recently identified as a novel anti‐cancer drug.
Haofeng Lu   +7 more
doaj   +1 more source

Identification of the metabolites of ivermectin in humans

open access: yesPharmacology Research & Perspectives, 2021
Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites.
Phornpimon Tipthara   +9 more
doaj   +1 more source

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