Results 11 to 20 of about 25,487 (235)

Dupilumab‐induced skin‐associated side effects in patients with chronic rhinosinusitis with nasal polyposis

open access: yesThe Journal of Dermatology, Volume 50, Issue 1, Page 89-93, January 2023., 2023
Abstract Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a typical type‐2 inflammation involving T‐helper type‐2 cells and impairing quality of life due to nasal obstruction, discharge and reduced sense of smell. Recently, the anti‐IL4Rα antibody dupilumab was approved for CRSwNP.
David Chromy   +7 more
wiley   +1 more source

Perspectives on rosacea patient characteristics and quality of life using baseline data from a phase 3 clinical study conducted in Japan

open access: yesThe Journal of Dermatology, Volume 49, Issue 12, Page 1221-1227, December 2022., 2022
Abstract There is a lack of contemporary data on rosacea originating in Japan. Using baseline data from a randomized, phase 3 study of 130 Japanese patients with rosacea treated with metronidazole gel (0.75%) or vehicle, the authors evaluated demographic and clinical characteristics, pretreatment quality of life, and exacerbating factors.
Kenshi Yamasaki, Yoshiki Miyachi
wiley   +1 more source

A comprehensive review of Strongyloides stercoralis infection after solid organ and hematopoietic stem cell transplantation

open access: yesClinical Transplantation, Volume 36, Issue 11, November 2022., 2022
Abstract Background We reviewed the scientific literature to gain insight on the epidemiology and outcome of Strongyloides stercoralis infections after transplantation. Methods CINAHL, PUBMED, and OVID/MEDLINE were reviewed from inception through March 31, 2022 using key words Strongyloides and transplantation.
Cybele Lara R. Abad   +3 more
wiley   +1 more source

Does apple replant disease affect the soil patch selection behaviour and population growth of Collembolans?

open access: yesJournal of Applied Entomology, Volume 147, Issue 1, Page 36-46, February 2023., 2023
Abstract Apple replant disease (ARD) is common to all major apple‐growing regions in the world. It occurs when new apple trees are replanted on sites where previously the same or closely related crop species were grown. Biotic (fungi, bacteria and nematodes) and abiotic soil factors (poor soil structure, nutrition) contribute to the development and ...
Nilupuli Thushangi Wadu Thanthri   +1 more
wiley   +1 more source

Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

open access: yesParasites & Vectors, 2021
Background Despite remarkable success obtained with current malaria vector control strategies in the last 15 years, additional innovative measures will be needed to achieve the ambitious goals for malaria control set for 2030 by the World Health ...
Patricia Nicolas   +7 more
doaj   +1 more source

Canine and feline P‐glycoprotein deficiency: What we know and where we need to go

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 46, Issue 1, Page 1-16, January 2023., 2023
Abstract In 2001 the molecular genetic basis of so‐called “ivermectin sensitivity” in herding breed dogs was determined to be a P‐glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called “the MDR1 mutation.” We have learned a great deal about P‐glycoprotein's role in drug disposition since that discovery, namely that P ...
Katrina L. Mealey   +2 more
wiley   +1 more source

Ivermectin as an adjunct treatment for hospitalized adult COVID-19 patients: A randomized multi-center clinical trial

open access: yesAsian Pacific Journal of Tropical Medicine, 2021
Objective: To evaluate different doses of ivermectin in adult patients with mild COVID-19 and to evaluate the effect of ivermectin on mortality and clinical consequences. Methods: A randomized, double-blind, placebo-controlled, multicenter clinical trial
Morteza Shakhsi Niaee   +14 more
doaj   +1 more source

Chromatographic Quantification of Ivermectin and Pranziquantel in the Tablets Using Stability Indicating RP-HPLC Method [PDF]

open access: yesPharmaceutical Sciences, 2019
Background: A new stability indicating RP-HPLC based assay method was developed to quantify ivermectin and praziquantel simultaneously and applied effectively to tablets.
Naga Venkata Suresh Kumar Devaka   +1 more
doaj   +1 more source

Permethrin and Ivermectin for Scabies [PDF]

open access: yesNew England Journal of Medicine, 2010
In a remote aboriginal community in tropical northern Australia, a mother comes to the health center with her 4-year-old son, who has multiple sores on the skin of his arms and legs. He is treated with a single dose of intramuscular penicillin G benzathine and with the application of topical 5% permethrin cream over his whole body.
Currie, Bart J., McCarthy, James S.
openaire   +4 more sources

Identification of the metabolites of ivermectin in humans

open access: yesPharmacology Research & Perspectives, 2021
Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites.
Phornpimon Tipthara   +9 more
doaj   +1 more source

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