Results 21 to 30 of about 66,840 (318)

Current therapeutic applications and pharmacokinetic modulations of ivermectin [PDF]

Veterinary World, 2019
Ivermectin is considered to be a wonder drug due to its broad-spectrum antiparasitic activity against both ectoparasites and endoparasites (under class of endectocide) and has multiple applications in both veterinary and human medicine.
Khan Sharun, T. S. Shyamkumar, V. A. Aneesha, Kuldeep Dhama, Abhijit Motiram Pawde , Amar Pal   +5 more
doaj   +1 more source

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

Malaria Journal, 2023
Background Ivermectin (22,23-dihydroavermectin B1a: H2B1a) is an endectocide used to treat worm infections and ectoparasites including lice and scabies mites.
Charlotte Kern, Pie Müller, Carlos Chaccour, Matthias E. Liechti, Felix Hammann, Urs Duthaler   +5 more
doaj   +1 more source

Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19

American Journal of Therapeutics, 2021
Background: After COVID-19 emerged on U.S shores, providers began reviewing the emerging basic science, translational, and clinical data to identify potentially effective treatment options.
P. Kory, G. Meduri, J. Varon, J. Iglesias, P. Marik   +4 more
semanticscholar   +1 more source

Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer

Cell Death and Disease, 2022
Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. Although multiple signaling pathways modulated by ivermectin have been identified in tumor cells, few studies have focused on the exact target
Shidong Lv, Zeyu Wu, Mayao Luo, Yifan Zhang, Jianqiang Zhang, Laura E. Pascal, Zhou Wang, Qiang Wei   +7 more
doaj   +1 more source

Ivermectin Treatment and Sanitation Effectively Reduce Strongyloides stercoralis Infection Risk in Rural Communities in Cambodia [PDF]

, 2016
BACKGROUND: Strongyloides stercoralis is the only soil-transmitted helminth with the ability to replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous and its worldwide prevalence has recently been estimated
Char, Meng Chuor, Forrer, Armelle, Khieu, Virak, Marti, Hanspeter, Muth, Sinuon, Odermatt, Peter, Schindler, Christian, Schär, Fabian   +7 more
core   +6 more sources

Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

Parasites & Vectors, 2021
Background Despite remarkable success obtained with current malaria vector control strategies in the last 15 years, additional innovative measures will be needed to achieve the ambitious goals for malaria control set for 2030 by the World Health ...
Patricia Nicolas, Caroline Kiuru, Martin G. Wagah, Martha Muturi, Urs Duthaler, Felix Hammann, Marta Maia, Carlos Chaccour   +7 more
doaj   +1 more source

Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype

BMC Infectious Diseases, 2022
Background The role of ivermectin in the treatment of COVID-19 is still under debate, yet the drug has been widely used in some parts of the world, as shown by impressive market data.
M. S. Marcolino, K. Meira, N. S. Guimarães, Paula Perdigão Motta, Victor Schulthais Chagas, S. Kelles, Laura Caetano de Sá, R. Valacio, P. K. Ziegelmann   +8 more
semanticscholar   +1 more source

Social Media and COVID-19—Perceptions and Public Deceptions of Ivermectin, Colchicine and Hydroxychloroquine: Lessons for Future Pandemics

Antibiotics, 2022
The capacity for social media to influence the utilization of re-purposed medicines to manage COVID-19, despite limited availability of safety and efficacy data, is a cause for concern within health care systems.
N. Schellack, Morné Strydom, M. Pepper, Candice L. Herd, Candice Laverne Hendricks, E. Bronkhorst, J. Meyer, N. Padayachee, V. Bangalee, I. Truter, A. Ellero, Thulisa Myaka, Elysha Naidoo, B. Godman   +13 more
semanticscholar   +1 more source

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial

BMC Infectious Diseases, 2021
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has changed our lives. The scientific community has been investigating re-purposed treatments to prevent disease progression in coronavirus disease (COVID-19) patients.
J. Vallejos, R. Zoni, M. Bangher, Silvina Villamandos, A. Bobadilla, F. Plano, Claudia Campias, Evangelina Chaparro Campias, Maria Fernanda Medina, Fernando Achinelli, H. A. Guglielmone, J. Ojeda, Diego Farizano Salazar, Gerardo Andino, Pablo Kawerin, Silvana Dellamea, A. Aquino, Victor Flores, Carolina N. Martemucci, Silvina María Martinez, J. Segovia, Paola Itati Reynoso, Noelia Carolina Sosa, Mariana Elizabeth Robledo, Joaquina Maria Guarrochena, María Mercedes Vernengo, Natalia E. Ruiz Diaz, E. Meza, María Gabriela Aguirre   +28 more
semanticscholar   +1 more source

Chromatographic Quantification of Ivermectin and Pranziquantel in the Tablets Using Stability Indicating RP-HPLC Method [PDF]

Pharmaceutical Sciences, 2019
Background: A new stability indicating RP-HPLC based assay method was developed to quantify ivermectin and praziquantel simultaneously and applied effectively to tablets.
Naga Venkata Suresh Kumar Devaka, Vallabhaneni Madhusudhan Rao   +1 more
doaj   +1 more source