Results 41 to 50 of about 67,505 (283)

Ivermectin shows clinical benefits in mild to moderate COVID19: A randomised controlled double-blind, dose-response study in Lagos

medRxiv, 2021
Introduction: In vitro studies have shown the efficacy of Ivermectin (IV) to inhibit the SARS - CoV- 2 viral replication, but questions remained as to In-vivo applications.
O. Babalola, C. Bode, Adesuyi Adeyinka Ajayi, F. Alakaloko, I. Akase, E. Otrofanowei, O. Salu, W. Adeyemo, A. Ademuyiwa, S. Omilabu   +9 more
semanticscholar   +1 more source

Ivermectin and COVID-19: Keeping Rigor in Times of Urgency

American Journal of Tropical Medicine and Hygiene, 2020
Ivermectin and Novel Coronavirus Disease (COVID-19): Keeping Rigor in Times of Urgency.
Carlos J. Chaccour, F. Hammann, S. Ramón-García, N. R. Rabinovich   +3 more
semanticscholar   +1 more source

Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes

Pharmacological Reports, 2021
COVID-19 cases are on surge; however, there is no efficient treatment or vaccine that can be used for its management. Numerous clinical trials are being reviewed for use of different drugs, biologics, and vaccines in COVID-19.
H. Kaur, Nishant Shekhar, Saurabh Sharma, Phulen Sarma, A. Prakash, B. Medhi   +5 more
semanticscholar   +1 more source

Effects of larval exposure to sublethal doses of ivermectin on adult fitness and susceptibility to ivermectin in Anopheles gambiae s.s.

Parasites & Vectors, 2023
Background The effects of ivermectin (endectocide) on mosquito survival make it a potential new malaria vector control tool. The drug can be administered to mosquito disease vectors through blood hosts that include humans and livestock. Its increased use
Caroline Kiuru, Kelly Ominde, Martha Muturi, Lawrence Babu, Caroline Wanjiku, Carlos Chaccour, Marta Ferreira Maia   +6 more
doaj   +1 more source

The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review

Journal of antibiotics (Tokyo. 1968), 2021
Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention.
A. Zaidi, P. Dehgani-Mobaraki
semanticscholar   +1 more source

Ivermectin susceptibility and sporontocidal effect in Greater Mekong Subregion Anopheles

Malaria Journal, 2017
Background Novel vector control methods that can directly target outdoor malaria transmission are urgently needed in the Greater Mekong Subregion (GMS) to accelerate malaria elimination and artemisinin resistance containment efforts. Ivermectin mass drug
Kevin C. Kobylinski, Ratawan Ubalee, Alongkot Ponlawat, Chanyapat Nitatsukprasert, Siriporn Phasomkulsolsil, Thanaporn Wattanakul, Joel Tarning, Kesara Na-Bangchang, Patrick W. McCardle, Silas A. Davidson, Jason H. Richardson   +10 more
doaj   +1 more source

Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results. [PDF]

, 2005
In order to identify the factors influencing compliance with mass ivermectin treatment for onchocerciasis control, a cross-sectional study was carried out in Bushenyi District, Uganda. Data were collected by interviewing 839 individuals who were randomly
Ndyomugyenyi, Richard, Nuwaha, Fred, Okware, Joseph   +2 more
core   +1 more source

Plasma pharmacokinetic profile of fluralaner (Bravecto™) and ivermectin following concurrent administration to dogs

Parasites & Vectors, 2015
Background Fluralaner is a novel systemic ectoparasiticide for dogs providing immediate and persistent flea, tick and mite control after a single oral dose.
Feli M. Walther, Mark J. Allan, Rainer KA Roepke   +2 more
doaj   +1 more source

The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]

, 2014
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf, Agwuh, Basáñez, Basáñez, Bosshardt, Cattamanchi, Chib, Churcher, de Andrade, Debrah, Duke, Duke, Gardon, Gelman, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Mand, Mark J. Taylor, Martin Walker, María-Gloria Basáñez, Norton, Osei-Atweneboana, Plaisier, Plaisier, Roberts, Sabine Specht, Specht, Tamarozzi, Taylor, Taylor, Taylor, Taylor, Taylor, Thomas S. Churcher, van Rie, Wanji, Wearing, World Health Organization, Xia   +43 more
core   +2 more sources

Use of Ivermectin as a Potential Chemoprophylaxis for COVID-19 in Egypt: A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: The rate of secondary attacks of SARS-COV-2 is high among household close contacts. Social distancing, isolation and infection control measures are important for preventing exposure to infection, but insufficient.
Waheed M Shoumann, Abdelmonem Awad Hegazy, Ramadan M Nafae, Moustafa I Ragab, Saad R Samra, Dalia Anas Ibrahim, Tarek H AL-Mahrouky, Ashraf E Sileem   +7 more
doaj   +1 more source