Results 41 to 50 of about 66,840 (318)
Identification of the metabolites of ivermectin in humans
Pharmacology Research & Perspectives, 2021 Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites.
Phornpimon Tipthara +9 more
doaj +1 more source
Pharmacological Reports, 2021 COVID-19 cases are on surge; however, there is no efficient treatment or vaccine that can be used for its management. Numerous clinical trials are being reviewed for use of different drugs, biologics, and vaccines in COVID-19.
H. Kaur +5 more
semanticscholar +1 more source
Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes [PDF]
, 2014 Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster.
Biggin, P +5 more
core +8 more sources
Nematode control in suckler beef cattle over their first two grazing seasons using a targeted selective treatment approach [PDF]
, 2015 peer-reviewedBackground With concerns over the development of anthelmintic resistance in cattle nematode populations, we must re-examine our approach to nematode control in cattle.
Barrett, Damien +6 more
core +1 more source
Parasites & Vectors, 2023 Background The effects of ivermectin (endectocide) on mosquito survival make it a potential new malaria vector control tool. The drug can be administered to mosquito disease vectors through blood hosts that include humans and livestock. Its increased use
Caroline Kiuru +6 more
doaj +1 more source
Modelling the consequences of targeted selective treatment strategies on performance and emergence of anthelmintic resistance amongst grazing calves [PDF]
, 2016 The development of anthelmintic resistance by helminths can be slowed by maintaining refugia on pasture or in untreated hosts. Targeted selective treatments (TST) may achieve this through the treatment only of individuals that would benefit most from ...
Berk, Zoe +3 more
core +2 more sources
The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review
Journal of antibiotics (Tokyo. 1968), 2021 Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention.
A. Zaidi, P. Dehgani-Mobaraki
semanticscholar +1 more source
Parasites & Vectors, 2015 Background Fluralaner is a novel systemic ectoparasiticide for dogs providing immediate and persistent flea, tick and mite control after a single oral dose.
Feli M. Walther +2 more
doaj +1 more source
Transition from endemic behavior to eradication of malaria due to combined drug therapies: an agent-model approach [PDF]
, 2019 We introduce an agent-based model describing a susceptible-infectious-susceptible (SIS) system of humans and mosquitoes to predict malaria epidemiological scenarios in realistic biological conditions.
Lind, Pedro G. +3 more
core +2 more sources
Future Virology, 2021 Aim: COVID-19 is currently the biggest threat to mankind. Recently, ivermectin (a US FDA-approved antiparasitic drug) has been explored as an anti-SARS-CoV-2 agent.
Abhigyan Choudhury +6 more
semanticscholar +1 more source