Results 41 to 50 of about 25,487 (235)
, 2020 Discussion of scholar papers published on Ivermectin and of some news that we can find about its use for Covid-19. A list of clinical trials is also given. The discussion was made in a series of versions from 14 June to 27 July 2020. For what concerns scholar papers, we report among them a preprint posted on 10 June in MedRχiv, which concludes that ...
openaire +3 more sources
Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Frontiers in Molecular Neuroscience, 2012 Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
doaj +1 more source
Modernising the Design and Analysis of Prevalence Surveys for Neglected Tropical Diseases [PDF]
arXiv, 2023 Current WHO guidelines set prevalence thresholds below which a Neglected Tropical Disease can be considered to have been eliminated as a public health problem, and specify how surveys to assess whether elimination has been achieved should be designed and analysed, based on classical survey sampling methods.
arxiv
Impact of ivermectin components on Anopheles dirus and Anopheles minimus mosquito survival
Parasites & VectorsBackground Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. Racemic ivermectin is composed of two components, namely a major component (> 80%; ivermectin B1a), which has an ethyl group
Pattarapon Khemrattrakool +9 more
doaj +1 more source
Pest Management Science, EarlyView.A new polymeric nanoparticle formulation containing aminophenoxazinone DiS‐NH2 (2,2′‐disulfanediyldianiline) is proposed as a post‐emergence and contact bioherbicide for weed management in durum wheat. Abstract BACKGROUND Weed‐resistance phenomena have increased dramatically in recent years. Bioherbicides can offer a sustainable alternative to chemical
Aurelio Scavo +7 more
wiley +1 more source
Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?
Infectious Diseases of Poverty, 2019 Background There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in ...
Joseph Nelson Siewe Fodjo +5 more
doaj +1 more source
Ivermectin and Doxycycline Combination as a Promising Drug Candidate Against SARS-CoV-2 Infection: A Computational Study [PDF]
arXiv, 2020 In the present study, we have described how by using molecular docking and molecular dynamic (MD) simulation studies the combination drug of ivermectin and doxycycline can be used as a potential inhibitor for SARS-CoV-2 virus. In lieu of unavailability of specific cure of COVID-19 till now various possibilities for individual and combination drugs have
arxiv
Functional characterization of ivermectin binding sites in α1β2γ2L GABA(A) receptors
Frontiers in Molecular Neuroscience, 2015 GABAA receptors (GABAARs) are the major inhibitory neurotransmitter receptors in the brain and are therapeutic targets for many indications including sedation, anesthesia and anxiolysis.
Argel eEstrada, Joe eLynch
doaj +1 more source
Recognition of potential Covid-19 drug treatments through the study of existing protein-drug and protein-protein structures: an analysis of kinetically active residues [PDF]
arXiv, 2020 We report the results of our study of approved drugs as potential treatments for COVID 19, based on the application of various bioinformatics predictive methods. The drugs studied include chloroquine, ivermectin, remdesivir, sofosbuvir, boceprevir, and {\alpha}-difluoromethylornithine (DMFO).
arxiv
Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients.
PLoS ONE, 2020 Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not ...
Daniel Camprubí +8 more
doaj +1 more source