Results 61 to 70 of about 67,505 (283)
Ivermectin: A Multifaceted Drug With a Potential Beyond Anti-parasitic Therapy
CureusIvermectin was first discovered in the 1970s by Japanese microbiologist Satoshi Omura and Irish parasitologist William C. Campbell. Ivermectin has become a versatile pharmaceutical over the past 50 years.
Baneet Kaur, Cyril Blavo, Mayur Parmar
semanticscholar +1 more source
PLoS Neglected Tropical Diseases, 2021 Background Oral ivermectin is a safe broad spectrum anthelminthic used for treating several neglected tropical diseases (NTDs). Currently, ivermectin use is contraindicated in children weighing less than 15 kg, restricting access to this drug for the ...
P. Jittamala +32 more
semanticscholar +1 more source
Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?
Infectious Diseases of Poverty, 2019 Background There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in ...
Joseph Nelson Siewe Fodjo +5 more
doaj +1 more source
Comparison between the efficacy of ivermectin and other drugs in treatment of cutaneous leishmaniasis [PDF]
Iraqi Journal of Veterinary Sciences, 2009 The study was conducted to compare the efficacy of ivermectin with some drugs in treatment of cutaneous leishmaniasis in vitro and in Balb/ C mice. The cultivation of Leishmania tropica was done on Nove MacNeal-Nicole medium (NNN).
M. A. Kadir, H. S. Aswad, A. M. Al-Samarai and G. A. Al-Mula
doaj +1 more source
South African Medical Journal, 2022 Background. Ivermectin is an antiparasitic drug that has shown in vitro activity against COVID‑19. Clinical studies supporting ivermectin for COVID‑19 prevention and treatment are conflicting, with important limitations. Public support for ivermectin is
V Pillay-Fuentes Lorente +8 more
doaj +1 more source
Strategies for the control of Rhipicephalus microplus ticks in a world of conventional acaricide and macrocyclic lactone resistance [PDF]
, 2018 Infestations with the cattle tick, Rhipicephalus microplus, constitute the most important ectoparasite problem for cattle production in tropical and subtropical regions worldwide, resulting in major economic losses. The control of R.
Bhushan, Chandra +2 more
core +1 more source
A brief overview of current drug repurposing approaches for COVID-19 management [PDF]
, 2020 This brief overview is intended to shed light on the current drug repositioning (also called drug repurposing) in the therapeutics of the novel coronavirus disease which emerged in 2019 (COVID-19).
Rodrigues, Pedro da Fonseca Soares +1 more
core +2 more sources
Journal of Medical Virology, 2021 This trial compared the rate and time of viral clearance in subjects receiving a combination of nitazoxanide, ribavirin, and ivermectin plus Zinc versus those receiving supportive treatment.
H. Elalfy +14 more
semanticscholar +1 more source
Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Frontiers in Molecular Neuroscience, 2012 Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
doaj +1 more source
Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity [PDF]
, 2019 The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to develop novel compounds, among which
Bouzat, Cecilia Beatriz +2 more
core +1 more source