Results 141 to 150 of about 1,005 (158)

Influence of Stereoselective Pharmacokinetics in the Development and Predictability of an IVIVC for the Enantiomers of Metoprolol Tartrate

Pharmaceutical Research, 2000
To investigate the ability of an IVIVC developed with a racemate drug as well as each enantiomer in predicting the in vivo enantiomer drug performance.Dissolution of metoprolol extended release tablets with different release characteristics (e.g., fast (F), moderate (M), and slow (S)) was performed using USP Apparatus I, pH 1.2, 50 rpm.
N, Sirisuth, N D, Eddington
openaire   +2 more sources

An Accelerated Release Method of Risperidone Loaded PLGA Microspheres with Good IVIVC

Current Drug Delivery, 2018
A long release period lasting several days or several weeks is always needed and thereby it is tedious and time consuming to screen formulations of such microspheres with so long release period and evaluate their release profiles in vitro with conventional long-term or "real-time" release method.
Xiaoqin, Hu, Jianwei, Zhang, Xuemei, Tang, Mingyuan, Li, Siyu, Ma, Cheng, Liu, Yue, Gao, Yue, Zhang, Yan, Liu, Fanglin, Yu, Yang, Yang, Jia, Guo, Zhiping, Li, Xingguo, Mei   +13 more
openaire   +2 more sources

PQRI Workshop Report: Application of IVIVC in Formulation Development

Dissolution Technologies, 2014
This article summarizes the proceeding of the September 2012 Workshop on Application of In vitro–In vivo correlation (IVIVC) in Formulation Development. The workshop brought together international experts with the goal of establishing common concepts that could be utilized to facilitate the development and validation of IVIVCs in the registration of ...
openaire   +1 more source

Intermediate release formulations of diclofenac potassium tablets for IVIVC.

Pakistan journal of pharmaceutical sciences, 2016
In recent days response surface methodology (RSM) has widely been applied for development and optimization of cost effective formulations with required quality. Study comprised of three steps including micromeritic comparison of different powder blends of placebo and diclofenac potassium (DP), formulation designing with CCRD (Design Expert, version 7.0.
Huma, Ali, Muhammad Harris, Shoaib, Farya, Zafar, Rabia, Bushra, Riffat, Yasmin, Shehla, Siddiqui, Zafar M, Alam   +6 more
openaire   +1 more source

IVIVC for circulation kinetics of liposomes

Journal of Controlled Release, 2011
openaire   +2 more sources

IVIVC of parenteral PLGA microspheres

Journal of Controlled Release, 2015
openaire   +2 more sources

IVIVR versus IVIVC

Dissolution Technologies, 2000
openaire   +1 more source

Study Design Considerations for IVIVC Studies

2005
Colm Farrell, Myriam Rochdi, Theresa Shepard   +2 more
openaire   +2 more sources

Comparison of Alternative Population Modeling Approaches for Implementing a Level A IVIVC and for Assessing the Time-Scaling Factor Using Deconvolution and Convolution-Based Methods

AAPS Journal, 2020
Roberto Gomeni, Françoise Bressolle-Gomeni, Gomeni Roberto   +2 more
exaly  

Level A in vitro-in vivo Correlation (IVIVC) Model with Bayesian Approach to Formulation Series

Journal of Pharmaceutical Sciences, 2006
Martti Marvola, A Urtti, Marjo Yliperttula   +2 more
exaly