Results 91 to 100 of about 1,243,353 (299)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Scandinavian Journal of Work and Organizational Psychology, 2019 Background: Working life today is characterized by acceleration and intensification due to social, and particularly technological, acceleration affecting the whole of society. These phenomena also affect working life by intensifying job demands, possibly
Saija Mauno +4 more
doaj +1 more source
Factors underlying the effect of organisational downsizing on health of employees: longitudinal cohort study [PDF]
, 2000 Objective: To explore the underlying mechanisms between organisational downsizing and deterioration of health of employees. Design: Longitudinal cohort study.
Ferrie, J.E. +3 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Work-related wellbeing in UK prison officers: a benchmarking approach [PDF]
, 2016 Purpose-The purpose of this paper is to examine the well-being of UK prison officers by utilising a benchmarking approach. Design/methodology/approach-The Health and Safety Executive (HSE) Stress Indicator Tool is widely used in the UK to assess key ...
Andrew James Clements +3 more
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in PsychologyIntroductionAlthough workload and emotional demands are recognized as key antecedents of job burnout, research focusing on preschool teachers has rarely compared their relative effects or explored whether burnout may function simultaneously as a mediator
Wen-Yu Hung +2 more
doaj +1 more source
Jurnal Studi Manajemen Organisasi, 2016 The aim of this research is to analyze the impact time demands of work, on job satisfaction, job stress, and employee turnover intention PT. Bank Tabungan Negara (Persero) Tbk.
Anisah Uswatun Hasanah
doaj +1 more source
Allocating Jobs with Periodic Demand Variations [PDF]
, 2015 In the context of service hosting in large-scale datacenters, we consider the problem faced by a provider for allocating services to machines. Based on an analysis of a public Google trace correspond-ing to the use of a production cluster over a long period, we propose a model where long-running services experience demand variations with a periodic ...
Beaumont, Olivier +3 more
openaire +1 more source
Ready for Tomorrow: Demand-Side Emerging Skills for the 21st Century [PDF]
, 2005 As part of the Ready for the Job demand-side skill assessment, the Heldrich Center explored emerging work skills that will affect New Jersey's workforce in the next three to five years.
Denise Pierson-Balik +6 more
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