Results 101 to 110 of about 1,863,226 (298)
Aspirations and job burnout: A study of New Zealand managers [PDF]
Self Determination Theory (SDT) asserts aspirations (life goals) of personal growth, relationship, community and health (intrinsic aspirations) support optimal functioning including in employees and leaders, whereas aspirations for wealth, image and fame
Haar, Jarrod, Roche, Maree
core +1 more source
IntroductionAlthough workload and emotional demands are recognized as key antecedents of job burnout, research focusing on preschool teachers has rarely compared their relative effects or explored whether burnout may function simultaneously as a mediator
Wen-Yu Hung +2 more
doaj +1 more source
Abstract: Artificial intelligence (AI) can function both as a job demand and as a job resource, with crucial implications for employees’ well-being and motivation. However, research has not yet investigated how employees appraise AI in these terms and whether their appraisals are malleable.
Franziska Schrade +2 more
openaire +1 more source
The Impact Of Job Demands And Resources On Job Crafting
Organizations are constantly under pressure for survival in the current highly volatile work environment. This change has been accelerated by trends such as smart work environments and artificial intelligence in the organizational context. Given such uncertainty deriving from a fast rate of change and high complexity, it is vital for organizations to ...
Sang-Hoon Lee +2 more
openaire +2 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Putting Tasks to the Test: Human Capital, Job Tasks and Wages [PDF]
Employing original, representative survey data, we document that cognitive, interpersonal and physical job task demands can be measured with high validity using standard interview techniques.
David H. Autor, Michael J. Handel
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Aim To investigate whether affective organizational commitment (AOC) among nursing home employees is enhanced by a health‐promoting work environment, conceptualized as high levels of job resources, work‐related sense of coherence (work‐SOC) and low ...
Karoline Grødal +3 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

