Results 111 to 120 of about 1,251,761 (300)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Overtime and Need for Recovery in Relation to Job Demands and Job Control
Journal of Occupational Health, 2006 Overtime and Need for Recovery in Relation to Job Demands and Job Control: Monique van der Hulst, et al. Department of Work and Organizational Psychology, Radboud University Nijmegen, The Netherlands—This study addressed the prevalence of working overtime in relation to psychosocial work characteristics and need for recovery. More precisely, the aim of
Hulst, M. van der +2 more
openaire +6 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Exploring demands from the perspective of employees identified as being at risk of burnout
International Journal of Qualitative Studies on Health & Well-Being, 2017 Purpose: Burnout has become an occupational health concern. However, little is known about the experiences of individuals identified as being at risk of burnout.
Cecile Gauche +2 more
doaj +1 more source
Zeitschrift für Arbeits- und Organisationspsychologie A&OAbstract: Artificial intelligence (AI) can function both as a job demand and as a job resource, with crucial implications for employees’ well-being and motivation. However, research has not yet investigated how employees appraise AI in these terms and whether their appraisals are malleable.
Franziska Schrade +2 more
openaire +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Nursing Open, 2019 Aim To investigate whether affective organizational commitment (AOC) among nursing home employees is enhanced by a health‐promoting work environment, conceptualized as high levels of job resources, work‐related sense of coherence (work‐SOC) and low ...
Karoline Grødal +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Cumulative Effects of Job Characteristics on Health [PDF]
We present what we believe are the best estimates of how job characteristics of physical demands and environmental conditions affect individual’s health.
Jason M. Fletcher +2 more
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source