Results 121 to 130 of about 2,092,814 (293)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Job Demands and Resources Predict Flourishing and Turnover Intentions [PDF]

The Job Demands-Resources (JD-R) model suggests that job resources can buffer the detrimental effects of job demands. This remains untested in New Zealand within the context of the Covid-19 pandemic leaving researchers to question the importance of ...
Nicolls, Ceara, Haar, Jarrod, Wallis, Amanda   +2 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Job demand intensification and job satisfaction: engagement as a mediator

Frontiers in Psychology
Background New psychosocial risks that challenge employees’ well-being and performance. This study investigates the mediating role of work engagement in the relationship between job demand intensification and job satisfaction, while accounting for job insecurity and work–family conflict as antecedents among ...
Brito-Arancibia, Kiralina, Boada-Grau, Joan, Sora, Beatriz, Navarrete-Campos, Jean Paul   +3 more
openaire   +2 more sources

Psychosocial factors and work related sickness absence among permanent and non-permanent employees [PDF]

, 2004
Study objective: To examine the association between psychosocial work factors and work related sickness absence among permanent and non-permanent employees by sex.Design: A cross sectional survey conducted in 2000 of a representative sample of the ...
Benavides, FG, Benach, J, Amick, BC, Martinez, JM, Gimeno, D   +4 more
core  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Job demands–resources theory: Frequently asked questions.

Journal of Occupational Health Psychology
Job demands-resources (JD-R) theory is commonly used to predict employee well-being, work behaviors, and performance. This article provides a short description of JD-R theory and discusses issues and questions that have been raised regarding the theory.
Arnold B. Bakker, Evangelia Demerouti
openaire   +4 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Managing Vitality, Sustainable Performance and Fatigue in Nursing Home Staff: A Multi‐Location Cross‐Sectional Survey Study: Empirical Research Quantitative

Nursing Open
Aim This study examines the moderating role of specific job resources in the association between job demands, vigour, sustainable performance and fatigue in nursing home staff.
Jan deJonge, Ramona Backhaus, Jan P. H. Hamers   +2 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source