Results 121 to 130 of about 1,251,761 (300)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Family Supportive Supervision Around the Globe

, 2018
Family-supportive supervision (FSS) refers to the degree to which employees perceive their immediate supervisors as exhibiting attitudes and behaviors that are supportive of their family role demands (Hammer, Kossek, Zimmerman, & Daniels, 2007; Kossek ...
Hammer, Leslie B., Kossek, Ellen Ernst, Odle-Dusseau, Heather N.   +2 more
core  

Co-principals: Characteristics of Dual Leadership Teams [PDF]

, 2006
A co-principal leadership model has been suggested as one way to address the shortage of qualified educational leaders for our schools and the increased demands on those leaders.
Eckman, Ellen
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Managing Vitality, Sustainable Performance and Fatigue in Nursing Home Staff: A Multi‐Location Cross‐Sectional Survey Study: Empirical Research Quantitative

Nursing Open
Aim This study examines the moderating role of specific job resources in the association between job demands, vigour, sustainable performance and fatigue in nursing home staff.
Jan deJonge, Ramona Backhaus, Jan P. H. Hamers   +2 more
doaj   +1 more source

Women High School Principals: Perspectives on Role Conflict, Role Commitment, and Job Satisfaction [PDF]

, 2002
This study is an investigation of women high school principals in terms of the challenges they face, role conflicts they experience, their role commitment, and their job satisfaction. The purpose is to describe women high school principals addressing the
Eckman, Ellen
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

The Future of Millennial Jobs [PDF]

, 2014
The Future of Millennial Jobs explores the future of the labor force for Millennials and how higher education can better align with future job market demands. The report concludes that many young adults, ages 18 to 34 years-old, are uniquely prepared for
Konrad Mugglestone, Tom Allison
core  

Job demands–resources theory: Frequently asked questions.

Journal of Occupational Health Psychology
Job demands-resources (JD-R) theory is commonly used to predict employee well-being, work behaviors, and performance. This article provides a short description of JD-R theory and discusses issues and questions that have been raised regarding the theory.
Arnold B. Bakker, Evangelia Demerouti
openaire   +4 more sources