Results 81 to 90 of about 1,863,226 (298)

Perceived new demands associated with socioeconomic change: A challenge to job security?

open access: yes, 2018
Our study focuses on everyday manifestations of contemporary socioeconomic change. For a sample of young- and middle-aged German employees gathered in 2008 (N = 281), we investigate the relationship of perceived rising demands regarding (a) the labor ...
Silbereisen, Rainer K.   +2 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Motivations, work-family enrichment and job satisfaction: An indirect effects model [PDF]

open access: yes, 2011
Self Determination Theory (SDT) recognises that people may experience their motivations as either coming from within themselves (autonomous) or from outside of themselves (controlled).
Haar, Jarrod, Roche, Maree
core   +1 more source

Job Demands–Resources Model Affects the Performance of Associate Nurses in Hospital

open access: yesJurnal Keperawatan Indonesia, 2020
Low nurses’ performance is related with increased job demands and unprofessional job resources. This cross-sectional study aimed to analyze the effects of the job demands–resources model on the performance of associate nurses.
Khairunnisa Batubara   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Estimates of Wage Discrimination Against Workers with Sensory Disabilities, with Controls for Job Demands [PDF]

open access: yes
We provide the first-ever estimates of wage discrimination against workers with sensory (hearing, speech, vision) disabilities. Workers with sensory disabilities have lower probabilities of employment and lower wages, on average, than nondisabled workers.
BALDWIN Marjorie L., CHOE Chung
core   +2 more sources

Watch your Workers Win. Changing Job Demands and HRM Responses [PDF]

open access: yes
This paper considers how the demand for non-material aspects of jobs evolves over changing wealth levels and how firms may want to react. We first consider the importance of non-material job aspects in general before turning to two specifc human resource
Luke Haywood
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

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