Results 61 to 70 of about 2,092,814 (293)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Job demands and resources of vocational education teachers: the role of resilience and social support in well-being, job satisfaction, and burnout

Empirical Research in Vocational Education and Training
Background In their daily working lives, teachers are confronted with numerous job demands, including conflicts with individual colleagues or the school management, learners with high heterogeneity or a lack of motivation, and technical issues.
Max S. Lohner, Nina Marlene Sarochan, Carmela Aprea   +2 more
doaj   +1 more source

Job demands and resources of workers in a South African agricultural organisation

SA Journal of Human Resource Management, 2015
Orientation: Understanding the job demands and resources experienced by workers in an agricultural organisation. Research purpose: The objective of this study was to examine the validity and reliability of the Adapted Job Demands and Resources Scale ...
Doris N. Asiwe, Carin Hill, Lené I. Jorgensen   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A Longitudinal Test of the Demand–Control Model Using Specific Job Demands and Specific Job Control [PDF]

International Journal of Behavioral Medicine, 2010
Supportive studies of the demand-control (DC) model were more likely to measure specific demands combined with a corresponding aspect of control.A longitudinal test of Karasek's (Adm Sci Q. 24:285-308, 1) job strain hypothesis including specific measures of job demands and job control, and both self-report and objectively recorded well-being.Job strain
De Jonge, J., Van Vegchel, N., Shimazu, A., Dormann, C., Schaufeli, Wilmar   +4 more
openaire   +3 more sources

Job Demands x Job Control Interaction Effects: Do Occupation-specific Job Demands Increase their Occurrence?

, 2015
Despite evidence that the accurate assessment of occupational health should include measures of both generic job demands and occupation-specific job demands, most research includes only generic job demands.
Biggs, Amanda, Brough, Paula
core   +1 more source

Physicians' working conditions and job satisfaction : does hospital ownership in Germany make a difference? [PDF]

, 2009
Background: A growing number of German hospitals have been privatized with the intention of increasing cost effectiveness and improving the quality of health care.
Mache, Stefanie, Vitzthum, Karin, Groneberg, Jan David Alexander, Klapp, Burghard F., Nienhaus, Albert, Nienhaus Albert, Klapp Burghard F, David A Groneberg, Groneberg David A, Mache Stefanie, Vitzthum Karin, Burghard F Klapp, Stefanie Mache, Karin Vitzthum, Albert Nienhaus   +14 more
core   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Contextualising the job demands–resources model: a cross-sectional study of the psychosocial work environment across different healthcare professions

Human Resources for Health
Background The deteriorating psychosocial work environment among healthcare workers in Sweden, influenced by demanding working conditions and resource constraints, affects individual well-being and patient care quality.
Britta Elsert Gynning, Elin Karlsson, Kevin Teoh, Per Gustavsson, Filip Christiansen, Emma Brulin   +5 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source