Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peranan Tuntutan Kerja dan Sumber Daya Kerja terhadap Keterikatan Kerja Wanita Karir
Psikologika: Jurnal Pemikiran dan Penelitian Psikologi, 2016 The purpose of this study is to explore the role of job demands, job resources and work engagement among dual career women. The hypotheses to be tested was : 1 ) there is correlation between job demands and work engagement among dual career women, 2 ...
Annisaa Miranty Nurendra
doaj +1 more source
Examining the challenge-hindrance-threat distinction of job demands alongside job resources
Frontiers in Psychology, 2023 PurposePrevious research conducted on the Job Demands-Resources model has mostly ignored the newly introduced Challenge-Hindrance-Threat distinction of workplace stressors.
Martha Fernandez de Henestrosa +2 more
doaj +1 more source
The Relationship Between Individual Personality Characteristics and Person-Job Fit Among Primary and Secondary School Teachers in New Zealand [PDF]
, 2012 Research has shown that individual personality characteristics are strongly related to an employee’s affective and behavioural responses to the job and/or workplace (Barrick & Mount, 1991; Judge & Bono, 2001, Kumar & Bakhshi, 2010).
Chan, Jing Yi (Daphne)
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Job Crafting, Work Engagement, Burnout: Mediating Role of Self-Efficacy
Studia Psychologica, 2020 Based on the Job Demands-Resources model (JD-R) the aim of this study was to verify work engagement and burnout prediction models in relation to self-efficacy and four job crafting strategies: increasing structural job resources, increasing challenging ...
Eva Rošková, Lucia Faragová
doaj +1 more source
Overeducation and job satisfaction: the role of job demands and control [PDF]
International Journal of Manpower, 2016 Purpose – The purpose of this paper is to investigate how job demands and control contribute to the relationship between overeducation and job satisfaction. Design/methodology/approach – The analysis is based on data for Belgian young ...
Verhaest, Dieter, Verhofstadt, Elsy
openaire +3 more sources
Impact of work design on psychological work reactions and job performance among technical workers: A longitudinal study in Malaysia [PDF]
, 2010 Work design has long been found to affect employee well-being, but scholars have begun to question whether the established theoretical relations regarding work design continue to hold given the enormous changes in the nature of work during the past two ...
Panatik, Siti Aisyah
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Religiousness in times of job insecurity: job demand or resource? [PDF]
Career Development International, 2014 Purpose– Departing from the job demands resources model, the purpose of this paper is to investigate whether religion, defined as strength of religious faith, can be viewed as resource or as demand. More specifically, the authors addressed the question as to how job insecurity and religion interact in predicting burnout and change-oriented behavior ...
Schreurs, B. +5 more
openaire +3 more sources