Results 161 to 170 of about 2,212,872 (284)

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level   +5 more
wiley   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan   +13 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su   +8 more
wiley   +1 more source

Mapping the ideal job: insights into job resources of general practitioner trainees. [PDF]

open access: yesScand J Prim Health Care
Öhman O   +4 more
europepmc   +1 more source

Job demands and job resources as antecedents of burnout [PDF]

open access: yes, 2019
Bu çalışmanın temel amacı iş taleplerinin (rol çatışması rol belirsizliği, iş yükü) ve iş kaynaklarının (yönetici desteği, iş arkadaşı desteği, iş özerkliği, kişisel gelişim fırsatları ve adalet algısının çalışanların tükenmişlik düzeyini (duygusal tükenme, duyarsızlaşma, kişisel başarıların düşmesi) tahmin etmede kullanılıp kullanılamamasıdır.Bilimsel
openaire   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

open access: yesAdvanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno   +16 more
wiley   +1 more source

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