Results 41 to 50 of about 97,726 (142)

Kidney Allograft Dysfunction Due to John Cunningham (JC) Virus Nephropathy

Cureus, 2022
John Cunningham (JC) polyomavirus-associated nephropathy (JC-PVAN) is a rare cause of polyomavirus-associated nephropathy (PVAN). Although BK polyomavirus (BKPyV) is a relatively proven common infection post kidney transplantation, JC polyomavirus (JCPyV) infection and its impact on graft function have been less studied.
Sharma, Neeraj, Abdulkhalek, Samer
openaire   +2 more sources

Cerebral lesions in hematological malignancies: a case report

Journal of Medical Case Reports, 2021
Background Progressive multifocal leukoencephalopathy is a rare central nervous system disease, resulting from reactivation of latent John Cunningham virus.
Nicoletta D’Ettore, Valentina Scheggi, Brunetto Alterini, Niccolò Marchionni   +3 more
doaj   +1 more source

Sequence analysis of the non-coding control region of John Cunningham virus isolates from patients with multiple sclerosis treated with natalizumab

Journal of microbiology, epidemiology and immunobiology, 2023
Introduction. The John Cunningham virus (JCPyV) causes a fatal demyelinating disease of the central nervous system known as progressive multifocal leukoencephalopathy (PML). In healthy people, the JCPyV non-coding control region (NCCR) is not rearranged,
M. Tyumentseva, A. Tyumentsev, M. Zakharova, L. Askarova, T. Simaniv, M. Piradov, Vasily G. Akimkin   +6 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy in a patient with novel mutation in the RAC2 gene: a case report

Journal of Medical Case Reports, 2022
Background Progressive multifocal leukoencephalopathy is a rare demyelinating disease that is often secondary to lytic destruction of oligodendrocytes and, to a lesser extent, to astrocytes’ response to human neurotrophic John Cunningham polyomavirus ...
Sima Bahrami, Saba Arshi, Mohammad Nabavi, Mohammad Hassan Bemanian, Morteza Fallahpour, Afshin Rezaeifar, Sima Shokri   +6 more
doaj   +1 more source

Hepatitis B virus-induced CD4 lymphocytopenia: A rare cause of progressive multifocal leukoencephalopathy

Asian Journal of Medical Sciences, 2022
Progressive multifocal leukoencephalopathy (PML) is a rare subacute-onset fatal demyelinating disease of the central nervous system caused by the John Cunningham (JC) virus.
Amar Kumar Mishra , Sanjay Kumar , Niraja Agasti , Gautam Guha , Saikat Ghosh , Bijendra Mohanty , Pideno S Ngullie , Joydeep Mukherjee   +7 more
doaj   +1 more source

New Algorithms Improving PML Risk Stratification in MS Patients Treated With Natalizumab

Frontiers in Neurology, 2020
Overview: We assessed the role of age and disease activity as new factors contributing to establish the risk of progressive multifocal leucoencephalopathy in multiple sclerosis patients treated with natalizumab in 36 University Hospitals in Europe.
Inmaculada Toboso, Amalia Tejeda-Velarde, Roberto Alvarez-Lafuente, Rafael Arroyo, Harald Hegen, Florian Deisenhammer, Susana Sainz de la Maza, José C. Alvarez-Cermeño, Guillermo Izquierdo, Dolores Paramo, Pedro Oliva, Bonaventura Casanova, Eduardo Agüera-Morales, Diego Franciotta, Matteo Gastaldi, Oscar Fernández, Patricia Urbaneja, José M. Garcia-Dominguez, Fernando Romero, Alicia Laroni, Antonio Uccelli, Angel Perez-Sempere, Albert Saiz, Yolanda Blanco, Daniela Galimberti, Elio Scarpini, Carmen Espejo, Xavier Montalban, Ludwig Rasche, Friedemann Paul, Friedemann Paul, Inés González, Elena Álvarez, Cristina Ramo, Ana B. Caminero, Yolanda Aladro, Carmen Calles, Pablo Eguía, Antonio Belenguer-Benavides, Lluis Ramió-Torrentà, Ester Quintana, José E. Martínez-Rodríguez, Agustín Oterino, Carlos López de Silanes, Luis I. Casanova, Lamberto Landete, Jette Frederiksen, Gabriel Bsteh, Patricia Mulero, Manuel Comabella, Miguel A. Hernández, Mercedes Espiño, José M. Prieto, Domingo Pérez, María Otano, Francisco Padilla, Juan A. García-Merino, Laura Navarro, Alfonso Muriel, Lucienne Costa Frossard, Luisa M. Villar   +60 more
doaj   +1 more source

Smoldering myeloma presenting as progressive multifocal leukoencephalopathy: a case report

Journal of Medical Case Reports, 2012
Introduction Progressive multifocal leukoencephalopathy is an opportunistic infection occurring in patients with severe cellular immunodeficiency. This case highlights the role of cellular immunodeficiency in the reactivation of John Cunningham virus in ...
Troppmann Martina, Büttner Roland, Böwer Michael, Salzberger Bernd   +3 more
doaj   +1 more source

Progressive Multifocal Leukoencephalopathy and Immune Reconstitution Inflammatory Syndrome after Discontinuation of Fingolimod

Case Reports in Neurology, 2022
Progressive multifocal leukoencephalopathy (PML) is a rare complication of immunosuppressive treatment in MS patients. Immune reconstitution inflammatory syndrome (IRIS) appears after the withdrawal of certain drugs such as natalizumab (NTZ) or ...
Raquel Piñar Morales, María Carrasco Garcia, Luis Gutierrez-Rojas, Francisco Javier Barrero Hernández   +3 more
doaj   +1 more source

HIGH PREVALENCE OF JOHN CUNNINGHAM VIRURIA IN RENAL TRANSPLANT RECIPIENTS

The Iraqi Journal of Medical Sciences, 2017
Background: John Cunningham virus (JCV) is one of the important viruses in immunocompromised patients. High JC viruria is seen in kidney allograft recipients; some of them with a polyomavirus associated nephropathy (PVAN) just like BK polyomavirus but to
Mervit B. Jasim, Ali J.H. Al-Saedi, Mustafa R. Hussein, Asmaa B. Al-Obaidi, Haider S. Kadhim   +4 more
doaj   +4 more sources

Molecular biomarkers in multiple sclerosis [PDF]

Arhiv za farmaciju, 2022
Multiple sclerosis (MS) is a highly heterogenous disease regarding radiological, pathological, and clinical characteristics and therapeutic response, including both the efficacy and safety profile of treatments.
Michaličková Danica, Kübra Öztürk Hatice, Das Debanjan, Osama Bukhari Syed, Slanař Ondřej   +4 more
doaj   +1 more source