PReS-FINAL-2291: Activation of TLR pathway JSLE derived neutrophil extracellular traps [PDF]
Pediatric Rheumatology, 2013 Juvenile Systemic Lupus Erythematous (JSLE) is characterised by auto-antibody production directed against nuclear auto-antigens. Toll-like receptors (TLRs) are pattern recognition receptors of the innate immune system responsible for initiating an immune response against invading pathogens.
Thorbinson, C, Midgley, A, Beresford, MW
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Biomarkers for systemic lupus erythematosus: A scoping review
Immunity, Inflammation and Disease, Volume 12, Issue 10, October 2024.Abstract Background In recent years, newly discovered potential biomarkers have great research potential in the diagnosis, disease activity prediction, and treatment of systemic lupus erythematosus (SLE). Objective In this study, a scoping review of potential biomarkers for SLE over several years has identified the extent to which studies on biomarkers
Su‐jie Zhang +2 more
wiley +1 more source
“You can't do this, you've arthritis":Exploring the experiences of education and employment of young people with arthritis [PDF]
, 2018 Introduction: Vocational development is an integral component of adolescence with several key educational transitions occurring during this stage of life.
Farre, Albert +4 more
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International Journal of Immunogenetics, Volume 51, Issue 2, Page 81-88, April 2024.Abstract To investigate the correlation between susceptibility to systemic lupus erythematosus (SLE) and single nucleotide polymorphisms (SNPs) rs699, rs4762 and rs1926723 in the AGT gene in the population of Northeast China, while also introducing a new method for early detection of SLE.
Huitao Wu +10 more
wiley +1 more source
PReS-FINAL-2301: Cardiac tamponade and auto-immune haemolysis as first presentation of JSLE [PDF]
Pediatric Rheumatology, 2013 This is a case report of a 14 year old girl who presented with cardiac tamponade and severe auto-immune Haemolytic anaemia at first presentation of Juvenile Systemic Lupus Erythematosus (JSLE).
Yiallourides, M, Shipman, J, Rangaraj, S
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Neutrophil function in juvenile systemic Lupus Erythematosus (JSLE) [PDF]
, 2014 Objectives This project aimed to investigate the abnormal neutrophil functions in terms of cell survival, phagocytosis, ROS production and chemotaxis in JSLE patients. Furthermore, factors that could affect normal neutrophil functions (such as patient sera, recombinant human cytokines and commonly-used medications) were investigated.
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1675 Real world treatment of juvenile systemic lupus erythematosus (JSLE): evidence from the UK JSLE cohort study [PDF]
Abstracts, 2021 Naomi Egbivwie +4 more
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Clinical predictors of active LN development in children – evidence from the UK JSLE Cohort Study
Lupus, 2018 Background Juvenile-onset systemic lupus erythematosus (JSLE) patients may develop lupus nephritis (LN) during their initial presentation, or later in their disease. This study aimed to assess whether clinical/demographic factors characterize patients with LN within the United Kingdom JSLE Cohort Study, and whether such factors predict subsequent LN ...
Smith, EMD +3 more
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Study of early atherosclerosis in juvenile-onset systemic lupus erythematosus patients
Egyptian Rheumatology and Rehabilitation, 2017 Objective The aim of this study was to investigate early atherosclerotic changes in juvenile-onset systemic lupus erythematosus (jSLE) patients and its relation with disease activity.
Emtethal A Said Ahmed +4 more
doaj +1 more source
RHUPUS Syndrome in Children: A Case Series and Literature Review
Case Reports in Rheumatology, 2013 Objective. Overlap of juvenile idiopathic arthritis (JIA) and juvenile systemic lupus erythematosus (JSLE) is a rare clinical condition in children. This condition has been described as RHUPUS syndrome.
Vahid Ziaee +2 more
doaj +1 more source