Results 61 to 70 of about 732 (166)

PReS-FINAL-2291: Activation of TLR pathway JSLE derived neutrophil extracellular traps [PDF]

open access: yesPediatric Rheumatology, 2013
Juvenile Systemic Lupus Erythematous (JSLE) is characterised by auto-antibody production directed against nuclear auto-antigens. Toll-like receptors (TLRs) are pattern recognition receptors of the innate immune system responsible for initiating an immune response against invading pathogens.
Thorbinson, C, Midgley, A, Beresford, MW
openaire   +1 more source

Bone mineral density in juvenile systemic lupus erythematosus

open access: yesBrazilian Journal of Medical and Biological Research, 2002
We evaluated spine bone mineral density (BMD) in Brazilian children with juvenile systemic lupus erythematosus (JSLE) in order to detect potential predictors of reduction in bone mass.
Castro T.C.M.   +6 more
doaj  

Study of early atherosclerosis in juvenile-onset systemic lupus erythematosus patients

open access: yesEgyptian Rheumatology and Rehabilitation, 2017
Objective The aim of this study was to investigate early atherosclerotic changes in juvenile-onset systemic lupus erythematosus (jSLE) patients and its relation with disease activity.
Emtethal A Said Ahmed   +4 more
doaj   +1 more source

Systemic lupus erythematosus with juvenile onset: current status of the problem (literature review)

open access: yesСовременная ревматология
Patients with juvenile-onset systemic lupus erythematosus (jSLE) account for up to 25% of all SLE patients. The main difference between jSLE and SLE in adults is the greater role of genetic factors in the pathogenesis, higher activity, earlier ...
M. I. Kaleda, I.  P. Nikishina
doaj   +1 more source

RHUPUS Syndrome in Children: A Case Series and Literature Review

open access: yesCase Reports in Rheumatology, 2013
Objective. Overlap of juvenile idiopathic arthritis (JIA) and juvenile systemic lupus erythematosus (JSLE) is a rare clinical condition in children. This condition has been described as RHUPUS syndrome.
Vahid Ziaee   +2 more
doaj   +1 more source

Função sexual e saúde reprodutiva em mulheres adolescentes com lúpus eritematoso sistêmico juvenil Sexual function and reproductive health in adolescent females with systemic lupus erythematosus

open access: yesRevista Brasileira de Reumatologia, 2009
OBJETIVO: Avaliar a função sexual e a saúde reprodutiva em adolescentes com Lúpus Eritematoso Sistêmico Juvenil (LESJ) e compará-las com controles.
Clovis Artur Almeida da Silva   +5 more
doaj   +1 more source

Desempenho diagnóstico e associações clínicas dos anticorpos contra componentes da cromatina no lúpus eritematoso sistêmico juvenil Diagnostic performance and clinical associations of antibodies to the chromatin antigenic system in juvenile systemic lupus erythematosus

open access: yesRevista Brasileira de Reumatologia, 2012
OBJETIVOS: Determinar a frequência de anticorpos contra componentes da cromatina no lúpus eritematoso sistêmico juvenil (LESJ) e correlacionar a presença desses autoanticorpos com manifestações clínicas e atividade da doença.
Silene Peres Keusseyan   +5 more
doaj   +1 more source

Juvenile Systemic Lupus Erythematosus (JSLE): A Literature Review

open access: yesMedical & Clinical Case Reports Journal
Juvenile systemic lupus erythematosus (JSLE) is a rare but clinically impactful autoimmune disease characterized by multisystem inflammation driven by dysregulated autoantibody production. Compared to adult-onset lupus, JSLE follows a more aggressive course, with earlier onset, severe visceral involvement and greater cumulative organ damage.
Sarila Hali Kloster Lopes   +13 more
openaire   +1 more source

A case of Juvenile Systemic Lupus Erythematosus in a pre-pubertal child with atopic eczema

open access: yesJournal of the Pakistan Medical Association
Juvenile Systemic Lupus Erythematosus (JSLE) is a subset of SLE, with onset before eighteen years of age and associated with increased mortality and morbidity. JSLE is a complex autoimmune disease with respect to its underlying genetics.
Ghazal Afzal   +2 more
doaj   +1 more source

Neutrophil function in juvenile systemic Lupus Erythematosus (JSLE) [PDF]

open access: yes, 2014
Objectives This project aimed to investigate the abnormal neutrophil functions in terms of cell survival, phagocytosis, ROS production and chemotaxis in JSLE patients. Furthermore, factors that could affect normal neutrophil functions (such as patient sera, recombinant human cytokines and commonly-used medications) were investigated.
openaire   +1 more source

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