Results 81 to 90 of about 1,352 (181)

Juvenile-onset SLE; disease activity, severity and damage - the UK JSLE Cohort Study

, 2012
<b>Objective</b> The UK JSLE Cohort Study is a multi-centre collaborative network established with the aim of improving the understanding of JSLE.
Baildam, Eileen M, Armon, Kate, Bailey, Kathryn, McDonagh, J.E., Riley, P., Wilkinson, Nick, Tizard, Jane, Archer, N., Rangaraj, Satyapal, Gardner-Medwin, J., Wilkinson, N., Ioannou, Yiannis, Sinha, M.D., Beresford, Michael W, Archer, Neil, Tizard, J., Pilkington, Clarissa, Cleary, G., Beresford, M.W., Pilkington, C., Sinha, Manish D, McCann, Liza J., Bailey, K., McCann, L.J., Beresford, Michael W., Tullus, Kjell, Baildam, E.M., McDonagh, Janet E, Sinha, Manish, Davidson, J., Leone, Valentina, Baildam, Eileen M., Armon, K., Gardner-Medwin, Janet, Davidson, Joyce, Leone, V., McDonagh, Janet E., Ioannou, Y., ?, ?, Cleary, Gavin, Tullus, K., Watson, L., Watson, Louise, Riley, Phil, Rangaraj, S., Mcdonagh, Janet, McCann, Liza J   +46 more
core   +1 more source

Juvenile-onset systemic lupus erythematosus (jSLE) – Pathophysiological concepts and treatment options

Best Practice & Research Clinical Rheumatology, 2017
The systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) manifests before the age of 16 years in 10-20% of all cases. Clinical courses are more severe, and organ complications are more common in patients with juvenile SLE. Varying gender distribution in different age groups and increasing severity with younger age and the ...
Hedrich, CM, Smith, EMD, Beresford, MW
openaire   +2 more sources

Clinical and laboratorial outcome of different age-onset systemic lupus erythematosus patients in Jiangsu, China: a multicentre retrospective study

Scientific Reports, 2022
Studies on clinical features of systemic lupus erythematosus among different age-onset patients are lacking in China. This multicentre study aimed to systemically compare clinical manifestations, comorbidities, organ involvement, and laboratory findings ...
Lihui Wen, Ziyan Chen, Ziyi Jin, Wenyou Pan, Lin Liu, Min Wu, Fuwan Ding, Huaixia Hu, Xiang Ding, Hua Wei, Yaohong Zou, Xian Qian, Meimei Wang, Jian Wu, Juan Tao, Jun Tan, Zhanyun Da, Miaojia Zhang, Jing Li, Xuebing Feng, Jun Liang, Huayong Zhang, Lingyun Sun   +22 more
doaj   +1 more source

PReS-FINAL-2291: Activation of TLR pathway JSLE derived neutrophil extracellular traps [PDF]

Pediatric Rheumatology, 2013
Juvenile Systemic Lupus Erythematous (JSLE) is characterised by auto-antibody production directed against nuclear auto-antigens. Toll-like receptors (TLRs) are pattern recognition receptors of the innate immune system responsible for initiating an immune response against invading pathogens.
Thorbinson, C, Midgley, A, Beresford, MW
openaire   +1 more source

Factors affecting bone mineral density in children and adolescents with systemic lupus erythematosus [PDF]

Annals of Pediatric Endocrinology & Metabolism
Purpose Patients with juvenile-onset systemic lupus erythematosus (JSLE) are at a high risk of entering adulthood with disease-related morbidities like reduced bone mass and osteoporosis.
Su Jin Park, Soo Yeun Sim, Dae Chul Jeong, Byung-Kyu Suh, Moon Bae Ahn   +4 more
doaj   +1 more source

Bone mineral density in juvenile systemic lupus erythematosus

Brazilian Journal of Medical and Biological Research, 2002
We evaluated spine bone mineral density (BMD) in Brazilian children with juvenile systemic lupus erythematosus (JSLE) in order to detect potential predictors of reduction in bone mass.
Castro T.C.M., Terreri M.T., Szejnfeld V.L., Castro C.H.M., Fisberg M., Gabay M., Hilário M.O.E.   +6 more
doaj  

Study of early atherosclerosis in juvenile-onset systemic lupus erythematosus patients

Egyptian Rheumatology and Rehabilitation, 2017
Objective The aim of this study was to investigate early atherosclerotic changes in juvenile-onset systemic lupus erythematosus (jSLE) patients and its relation with disease activity.
Emtethal A Said Ahmed, Sahar S Ganeb, Ahmed Y El-shambaky, Osama T Galal, Mai Y Tohamy   +4 more
doaj   +1 more source

Systemic lupus erythematosus with juvenile onset: current status of the problem (literature review)

Современная ревматология
Patients with juvenile-onset systemic lupus erythematosus (jSLE) account for up to 25% of all SLE patients. The main difference between jSLE and SLE in adults is the greater role of genetic factors in the pathogenesis, higher activity, earlier ...
M. I. Kaleda, I.  P. Nikishina
doaj   +1 more source

RHUPUS Syndrome in Children: A Case Series and Literature Review

Case Reports in Rheumatology, 2013
Objective. Overlap of juvenile idiopathic arthritis (JIA) and juvenile systemic lupus erythematosus (JSLE) is a rare clinical condition in children. This condition has been described as RHUPUS syndrome.
Vahid Ziaee, Mohammad Hassan Moradinejad, Reyhaneh Bayat   +2 more
doaj   +1 more source

Função sexual e saúde reprodutiva em mulheres adolescentes com lúpus eritematoso sistêmico juvenil Sexual function and reproductive health in adolescent females with systemic lupus erythematosus

Revista Brasileira de Reumatologia, 2009
OBJETIVO: Avaliar a função sexual e a saúde reprodutiva em adolescentes com Lúpus Eritematoso Sistêmico Juvenil (LESJ) e compará-las com controles.
Clovis Artur Almeida da Silva, Marília Vieira Febrônio, Eloísa Bonfá, Rosa Maria Rodrigues Pereira, Elsa Aida Gay de Pereira, Albertina Duarte Takiuiti   +5 more
doaj   +1 more source