A phage nucleus-associated RNA-binding protein is required for jumbo phage infection
bioRxiv, 2023 Large-genome bacteriophages (jumbo phages) of the Chimalliviridae family assemble a nucleus-like compartment bounded by a protein shell that protects the replicating phage genome from host-encoded restriction enzymes and CRISPR/Cas nucleases.
Eray Enustun +18 more
semanticscholar +3 more sources
A small bacteriophage protein determines the hierarchy over co-residential jumbo phage in Bacillus thuringiensis serovar israelensis. [PDF]
Commun Biol, 2022 Bacillus thuringiensis serovar israelensis is the most widely used biopesticide against insects, including vectors of animal and human diseases. Among several extrachromosomal elements, this endospore-forming entomopathogen harbors two bacteriophages: a ...
Pavlin A +10 more
europepmc +2 more sources
Microorganisms, 2023 Aeromonas salmonicida is the causative agent of septicemia in fish, and it is associated with significant economic losses in the aquaculture industry. While piscine Aeromonas infections are mainly treated with antibiotics, the emergence of resistance in ...
Vera Morozova +8 more
doaj +2 more sources
Pseudomonas Phage PaBG—A Jumbo Member of an Old Parasite Family [PDF]
Viruses, 2020 Bacteriophage PaBG is a jumbo Myoviridae phage isolated from water of Lake Baikal. This phage has limited diffusion ability and thermal stability and infects a narrow range of Pseudomonas aeruginosa strains.
Peter Evseev +6 more
doaj +3 more sources
The Phage Nucleus and PhuZ Spindle: Defining Features of the Subcellular Organization and Speciation of Nucleus-Forming Jumbo Phages [PDF]
Frontiers in Microbiology, 2021 Bacteriophages and their bacterial hosts are ancient organisms that have been co-evolving for billions of years. Some jumbo phages, those with a genome size larger than 200 kilobases, have recently been discovered to establish complex subcellular ...
Vorrapon Chaikeeratisak +3 more
doaj +3 more sources
Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome [PDF]
Frontiers in Veterinary ScienceGut microbiome research has historically focused on bacterial communities. In contrast, the roles of viruses, especially jumbo phages, remain poorly understood.
Chao Wei, Zhe Chen
doaj +2 more sources
3D structure of three jumbo phage heads.
Journal of General Virology, 2020 Jumbo phages are bacteriophages that carry more than 200 kbp of DNA. In this study we characterized two jumbo phages (ΦRSL2 and ΦXacN1) and one semi-jumbo phage (ΦRP13) at the structural level by cryo-electron microscopy. Focusing on their capsids, three-
E. Neumann +6 more
semanticscholar +5 more sources
Gastrointestinal jumbo phages possess independent synthesis and utilization systems of NAD+
MicrobiomeBackground Jumbo phages, phages with genomes > 200 kbp, contain some unique genes for successful reproduction in their bacterial hosts. Due to complex and massive genomes analogous to those of small-celled bacteria, how jumbo phages complete their life ...
Cunyuan Li +11 more
doaj +4 more sources
Isolation protocol of jumbo phage from winter grass soil [PDF]
IOP Conference Series: Earth and Environmental Science, 2021 Jumbo phage can isolated by two different methods and protocols. It depends on size, phage species, substrate sources, environment, media and tools. Each method has positive and negative results within each factors.
A. Wafa, M. A., H. Addy, T. Kawasaki
semanticscholar +2 more sources
Pseudomonas aeruginosa PA5oct Jumbo Phage Impacts Planktonic and Biofilm Population and Reduces Its Host Virulence. [PDF]
Viruses, 2019 The emergence of phage-resistant mutants is a key aspect of lytic phages-bacteria interaction and the main driver for the co-evolution between both organisms.
Olszak T +10 more
europepmc +2 more sources