Results 81 to 90 of about 98,997 (145)

The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges

open access: yesAdvanced Genetics, Volume 6, Issue 4, December 2025.
This article examines how the respiratory virome contributes to health and disease, highlighting its interactions with the host and bacteriome. Key disease associations and present knowledge gaps are outlined. The review discusses challenges in sample collection and preprocessing, and presents future research directions for understanding virome ...
Xiaoxuan Yao, Xiaohui Zou, Bin Cao
wiley   +1 more source

The human oral phageome is highly diverse and rich in jumbo phages [PDF]

open access: yes, 2020
AbstractUntil recently, the contribution of bacteriophages to the composition and function of the human microbiome has been largely overlooked. Recent developments in discovering novel bacteriophages from human metagenomes have been mostly focused on the gut.
Victoria R. Carr   +5 more
openaire   +1 more source

High‐throughput generic single‐entity sequencing using droplet microfluidics

open access: yesiMeta, Volume 4, Issue 6, December 2025.
We present Generic Single Entity Sequencing (GSE‐Seq), a droplet‐based workflow that generates monoclonal barcodes by one‐step PCR, performs dissolvable hydrogel‐enabled reactions for genome processing, and attaches barcodes during in‐droplet library preparation. Barcoded fragments are pooled and sequenced with PacBio long‐read sequencing. Barcodes are
Guoping Wang   +14 more
wiley   +1 more source

Phenotypical and Genomic Characterization of the Mollusk Pathogen Francisella halioticida

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
Phenotypic and genetic characterization of French isolates of Francisella halioticida and comparison with Canadian and Japanese strains. The study revealed similarities between FR22s and previous isolates but distinct differences with FR21. A major finding is the absence of the Francisella pathogenicity island in the less virulent isolate, FR22b ...
Hélène Bouras   +7 more
wiley   +1 more source

Advancing Tuberculosis Chemotherapy: Targeted Nanomedicines for the Mycobacterium TB Granuloma

open access: yesSmall, Volume 21, Issue 49, December 10, 2025.
This graphical abstract illustrates nanosystems used for targeted drug delivery into tuberculosis granulomas. It shows how targeting is influenced by size, pH, redox sensitivity, and surface charge. Various nanoparticles are incorporated with drugs to enhance penetration, stability, and release.
Shreya Ranjith Singh   +3 more
wiley   +1 more source

Population Dynamics between Erwinia amylovora, Pantoea agglomerans and Bacteriophages: Exploiting Synergy and Competition to Improve Phage Cocktail Efficacy

open access: yesMicroorganisms, 2020
Bacteriophages are viruses capable of recognizing with high specificity, propagating inside of, and destroying their bacterial hosts. The phage lytic life cycle makes phages attractive as tools to selectively kill pathogenic bacteria with minimal impact ...
Steven Gayder   +4 more
doaj   +1 more source

Immunomodulatory Biomaterials for Bone and Soft Tissue Chronic Inflammation Diseases

open access: yesSmall Science, Volume 5, Issue 12, December 2025.
This review analyzes immunomodulatory biomaterial strategies for treating chronic inflammatory disorders in bone and soft tissues. It explores emerging mechanisms for resolving inflammation while promoting tissue regeneration, offering insights for developing targeted immunotherapeutic approaches that bridge material science with immunology for ...
Yiming Li   +7 more
wiley   +1 more source

Variations of the Virome in Raw and Treated Water: A One‐Year Follow‐Up at Six Different Drinking Water Treatment Plants

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 6, December 2025.
This paper describes monitoring of outgoing water from drinking water treatment plants, geographically spread over half of Sweden and sampled every other month for 1 year. We found differences in the virome from the different water sources from each plant as well as differences in virus size and seasonal variation, where we also could detect viruses in
Fredy Saguti   +10 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

Distance‐Dependent Interaction between a Single Emitter and a Single Dielectric Nanoparticle Using DNA Origami

open access: yesSmall Structures, Volume 6, Issue 11, November 2025.
In this study, dielectric nanoantennas made of silicon nanoparticles are explored as low‐loss alternatives to traditional metallic ones. Using DNA origami, their interaction with fluorophores at the single‐molecule level is investigated, observing enhanced decay rates with high quantum yield amid minimal quenching.
Nicole Siegel   +10 more
wiley   +1 more source

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