Larger Than Life: Isolation and Genomic Characterization of a Jumbo Phage That Infects the Bacterial Plant Pathogen, Agrobacterium tumefaciens. [PDF]
Attai H +5 more
europepmc +1 more source
Phage isolation and functional characterization reveal strong antibiofilm activity against <i>Pseudomonas aeruginosa</i> in a cystic fibrosis sputum model. [PDF]
Bowder M +3 more
europepmc +1 more source
Antivirulence Activity and Therapeutic Potential of Jumbo <i>Vibrio</i> Phage pVa-22 against <i>Vibrio alginolyticus</i>. [PDF]
Jo SJ, Kwon J, Park SC, Kim SG.
europepmc +1 more source
Large-scale analysis of bacterial genomes reveals thousands of lytic phages. [PDF]
Perfilyev A +18 more
europepmc +1 more source
A novel lineage of large aquatic bacteriophages identified through metagenomics. [PDF]
Perez-Hernandez C +3 more
europepmc +1 more source
Publisher Correction: Therapeutic application of a jumbo bacteriophage against metallo-β-lactamase producing Pseudomonas aeruginosa clinical isolates. [PDF]
Paranos P +9 more
europepmc +1 more source
The bacteriophage T4 homologous recombination system: mechanism, applications, conservation, and environmental significance. [PDF]
Morrical SW.
europepmc +1 more source
Discovery of phage defense systems through component modularity networks
van den Berg DF +5 more
europepmc +1 more source
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Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection
Molecular Cell, 2022SUMMARYBacteria have diverse defences against phages. In response, jumbo phages evade multiple DNA-targeting defences by protecting their DNA inside a nucleus-like structure. We previously demonstrated that RNA-targeting type III CRISPR–Cas systems provide jumbo phage immunity by recognising viral mRNA exported from the nucleus for translation.
David Mayo-Muñoz +9 more
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In this Quick guide, Harding et al. introduce jumbo phages - the overlooked giants of the phage universe.
Kate R, Harding +2 more
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