Results 71 to 80 of about 5,614 (215)
Exploring the druggability of the UEV domain of human TSG101 in search for broad‐spectrum antivirals
Protein Science, Volume 34, Issue 1, January 2025.Abstract The ubiquitin E2 variant domain of TSG101 (TSG101‐UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101‐UEV/PTAP interactions has emerged as a promising strategy for the development of host‐oriented broad‐spectrum antivirals with low susceptibility to ...
Fernando Montero +17 more
wiley +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Experience of study and possible ways of elimination of false positive and false negative results during execution of polymerase chain reaction on an example of Junin virus RNA detection. Materials and methods.
T. E Sizikova +4 more
doaj
Nipah Virus Infection Generates Ordered Structures in Cellulo
Viruses, 2022 Nipah virus (NiV) is a zoonotic paramyxovirus with a fatality rate of up to 92% in humans. While several pathogenic mechanisms used by NiV to counteract host immune defense responses have been described, all of the processes that take place in cells ...
Cecilia Alejandra Vázquez +12 more
doaj +1 more source
Post-translational processing of the glycoproteins of lymphocytic choriomeningitis virus. [PDF]
, 1990 Intracellular events in the synthesis, glycosylation, and transport of the lymphocytic choriomeningitis virus (LCMV) glycoproteins have been examined. We have shown by N-glycanase digestion that LCMV strain Arm-4 bears five oligosaccharides on GP-1 and ...
Buchmeier, MJ +3 more
core
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression [PDF]
, 2017 Immune-mediated effector molecules can limit cancer growth, but lack of sustained immune activation in the tumour microenvironment restricts antitumour immunity.
Gassa, Asmae +8 more
core +1 more source
Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.Due to its intricacy and long‐term usefulness, traditional medicine continues to be practiced in several nations. Among the many medicinal plants found in the Dhofar region of Oman, the aromatic oleo‐gum resin generated by Boswellia sacra, commonly referred to as frankincense, stands out for its medical and commercial significance. Resin‐carrying ducts
Foziya Khan, Luay Rashan, Kuldeep Singh
wiley +1 more source
Revista Peruana de Medicina Experimental y Salud Pública, 2015 The Argentine hemorrhagic fever (AHF) is a severe acute viral disease caused by the Junin virus of the Arenaviridae family. The AHF endemic area coincides geographically with the largest grain export agro-industrial complex of the country [Argentina ...
Ana Briggiler +6 more
doaj +1 more source
National Seroprevalence and Risk Factors of Bluetongue Virus in Domestic Ruminants of Peru
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Bluetongue (BT) is a viral infection caused by the bluetongue virus (BTV) that affects domestic and wild ruminants worldwide. It is primarily transmitted by Culicoides spp. midges, and its infection is highly prevalent across temperate and tropical regions.
Dennis A. Navarro-Mamani +13 more
wiley +1 more source
Die Rolle des Signalpeptids für die Reifung des Lassavirus Glykoproteins [PDF]
, 2004 Das Oberflächenglykoprotein des Lassavirus ist ein Typ 1-Membranprotein. Es wird als Vorläufer präGP-C synthetisiert und posttranslational mit N-Glykanen modifiziert.
Buckel, Wolfgang (Prof. Dr.) +1 more
core +1 more source
La schizophrénie touche aussi les enfants et les adolescents : une des modalités de leur prise en charge est assurée par le CTJA [Centre thérapeutique de jour pour adolescents] [PDF]
, 2004 1% des schizophrénies se déclenchent avant l'âge de 10 ans. 20%, une sur cinq, commencent avant l'âge de 18 ans. Et dans 40% des cas de schizophrénie avérée, les premiers signes étaient apparus avant 18 ans.
Dunand, Fabien, Holzer, Laurent
core