Results 61 to 70 of about 5,647 (215)
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
PLoS Pathogens, 2018 Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a ...
Ikenna G Madu +13 more
doaj +1 more source
PLoS Pathogens, 2021 Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro infection by a number of pathogenic viruses, including New World and Old ...
Nicolás Sarute +6 more
doaj +1 more source
Small-Molecule Probes Targeting the Viral PPxY-Host Nedd4 Interface Block Egress of a Broad Range of RNA Viruses. [PDF]
, 2014 Budding of filoviruses, arenaviruses, and rhabdoviruses is facilitated by subversion of host proteins, such as Nedd4 E3 ubiquitin ligase, by viral PPxY late (L) budding domains expressed within the matrix proteins of these RNA viruses.
Davis, Benjamin +11 more
core +2 more sources
Aquaculture in Peru: Situation, Challenges and Prospects
Aquaculture, Fish and Fisheries, Volume 5, Issue 3, June 2025.ABSTRACT Aquaculture in Peru is a sector with significant growth and development in recent years. However, it faces multiple challenges to ensure its sustainability. This study aims to characterize the Peruvian aquaculture system by analysing the public, private and educational stakeholders involved, as well as the productive, commercial and ...
Euler Dolores‐Salinas +1 more
wiley +1 more source
Rapid Sequence Identification of Potential Pathogens Using Techniques from Sparse Linear Algebra
, 2015 The decreasing costs and increasing speed and accuracy of DNA sample collection, preparation, and sequencing has rapidly produced an enormous volume of genetic data. However, fast and accurate analysis of the samples remains a bottleneck. Here we present
Chiu, Nelson +4 more
core +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür +6 more
wiley +1 more source
Pests and diseases affecting potato landraces and bred varieties grown in Peru under indigenous farming system [PDF]
, 2015 The major pests and diseases were identified and quantified on thirteen potato landraces and three bred varieties cultivated in Peru. Late blight (Phytophthora infestans) was the primary biotic constraint affecting plants before flowering with an average
Andrade-Piedra, J.L. +4 more
core +1 more source
Enzootic Transmission of Yellow Fever Virus in Peru
Emerging Infectious Diseases, 2003 The prevailing paradigm of yellow fever virus (YFV) ecology in South America is that of wandering epizootics. The virus is believed to move from place to place in epizootic waves involving monkeys and mosquitoes, rather than persistently circulating ...
Juliet E. Bryant +6 more
doaj +1 more source
Protection Conferred against Junin Virus Infection in Rats
Intervirology, 1984 2-day-old Wistar rats intracerebrally infected with the XJC13 strain of virus exhibited a 5% survival rate which rose to 71% after immune serum treatment. Brain viral titers were relatively unaffected by this treatment. Histologic studies showed necrosis in the cerebellum and brain cortex with mononuclear cell infiltration in both treated and ...
J L, Blejer +3 more
openaire +2 more sources