Results 81 to 90 of about 2,720 (165)

EHA2024 Hybrid Congress

HemaSphere, Volume 8, Issue S1, June 2024.
wiley   +1 more source

Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs. [PDF]

J Virol, 2021
Gowen BB, Hickerson BT, York J, Westover JB, Sefing EJ, Bailey KW, Wandersee L, Nunberg JH.   +7 more
europepmc   +1 more source

Immunogenicity of recombinant vesicular stomatitis virus-vectored vaccines expressing the Machupo virus glycoprotein in different genome positions

Journal of Virology
Recombinant vesicular stomatitis virus (rVSV) is a powerful vaccine platform that elicits durable cellular and humoral immune responses. rVSV vaccines have successfully been used for various hemorrhagic fever-causing viruses. Here, we create and evaluate
Rachel Erickson, Paul Bates
doaj   +1 more source

A review of emerging health threats from zoonotic New World mammarenaviruses

BMC Microbiology
Despite repeated spillover transmission and their potential to cause significant morbidity and mortality in human hosts, the New World mammarenaviruses remain largely understudied.
Arianna Lendino, Adrian A. Castellanos, David M. Pigott, Barbara A. Han   +3 more
doaj   +1 more source

[Immunopathology induced in the rat by Junin virus].

Revista Argentina de microbiologia, 1991
Intra-cerebral infection of the 10-day-old rat with the XJ prototype strain of Junin virus induces an immunopathological encephalitis with 100% mortality. In contrast with previous observations, our present work with antithymocyte serum (ATS) demonstrates a pathological role for the cellular immune response in this experimental model.
M C, Remesar, J L, Blejer, M R, Nejamkis
openaire   +1 more source

Bovine Serum Albumin Nanoparticle-Mediated Delivery of Ribavirin and Mycophenolic Acid for Enhanced Antiviral Therapeutics

Viruses
The global spread of viral diseases is a public health issue. Ribavirin (RBV) and mycophenolic acid (MPA) are well-known wide-spectrum antiviral agents.
Mayra A. Castañeda Cataña, Andrea P. Rivas Marquina, Martín M. Dodes Traian, M. Josefina Carlucci, Elsa B. Damonte, Oscar E. Pérez, Eva C. Arrua, Claudia S. Sepúlveda   +7 more
doaj   +1 more source

Development of horse neutralizing immunoglobulin and immunoglobulin fragments against Junín virus. [PDF]

Antiviral Res, 2020
Pan X, Wu Y, Wang W, Zhang L, Xiao G.
europepmc   +1 more source

Multi-epitope-based vaccine designing against Junín virus glycoprotein: immunoinformatics approach

Future Journal of Pharmaceutical Sciences
Background The Junín virus (JUNV) is well known for causing argentine haemorrhagic fever (AHF), a severe endemic disease in farming premises. The glycoprotein of JUNV is an important therapeutic target in vaccine design.
Mallari Praveen
doaj   +1 more source

Development of a Reverse Genetic System to Generate Recombinant Chimeric Tacaribe Virus that Expresses Junín Virus Glycoproteins. [PDF]

Pathogens, 2020
Foscaldi S, Loureiro ME, Sepúlveda C, Palacios C, Forlenza MB, López N.   +5 more
europepmc   +1 more source

Guinea Pig Transferrin Receptor 1 Mediates Cellular Entry of Junín Virus and Other Pathogenic New World Arenaviruses. [PDF]

J Virol, 2020
Hickerson BT, Westover JB, Wang Z, Lee YM, Gowen BB.   +4 more
europepmc   +1 more source