Results 71 to 80 of about 5,647 (215)

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

WIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus, Eliana Dukhno, Rupali Kapoor, Piotr Gerlach   +3 more
wiley   +1 more source

EXPERIENCE OF STUDY AND POSSIBLE WAYS OF ELIMINATION OF FALSE POSITIVE AND FALSE NEGATIVE RESULTS DURING EXECUTION OF POLYMERASE CHAIN REACTION ON AN EXAMPLE OF JUNIN VIRUS RNA DETECTION

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Experience of study and possible ways of elimination of false positive and false negative results during execution of polymerase chain reaction on an example of Junin virus RNA detection. Materials and methods.
T. E Sizikova, V. N Lebedev, V. B Pantyukhov, S. V Borisevich, V. A Merkulov   +4 more
doaj  

Application of multiplex realtime PCR detection for hemorrhagic fever syndrome viruses

Journal of Infection and Public Health, 2023
Background: Multiplex real-time PCR is a quick and cost effective method for detection of various gene simultaneously. HFSV (Hemorrhagic Fever Syndrome Virus) is a newly emerging infectious disease because of globalization and climate change. We tried to
Yoonhyuk Choi, Younghee Kim
doaj   +1 more source

Exploring the druggability of the UEV domain of human TSG101 in search for broad‐spectrum antivirals

Protein Science, Volume 34, Issue 1, January 2025.
Abstract The ubiquitin E2 variant domain of TSG101 (TSG101‐UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101‐UEV/PTAP interactions has emerged as a promising strategy for the development of host‐oriented broad‐spectrum antivirals with low susceptibility to ...
Fernando Montero, Marisa Parra‐López, Alejandro Rodríguez‐Martínez, Javier Murciano‐Calles, Pedro Buzon, Ziying Han, L.‐Y. Lin, Maria C. Ramos, Javier Ruiz‐Sanz, Jose C. Martinez, Marco Radi, Christiane Moog, Sandra Diederich, Ronald N. Harty, Horacio Pérez‐Sánchez, Francisca Vicente, Francisco Castillo, Irene Luque   +17 more
wiley   +1 more source

New transmission scenarios of the argentine hemorrhagic fever since the introduction of the live attenuated junin virus vaccine (candid #1): an experience in migrant workers

Revista Peruana de Medicina Experimental y Salud Pública, 2015
The Argentine hemorrhagic fever (AHF) is a severe acute viral disease caused by the Junin virus of the Arenaviridae family. The AHF endemic area coincides geographically with the largest grain export agro-industrial complex of the country [Argentina ...
Ana Briggiler, Anabel Sinchi, Florencia Coronel, Zaida Sánchez, Silvana Levis, Jorge Taylor, Delia Enria   +6 more
doaj   +1 more source

Nipah Virus Infection Generates Ordered Structures in Cellulo

Viruses, 2022
Nipah virus (NiV) is a zoonotic paramyxovirus with a fatality rate of up to 92% in humans. While several pathogenic mechanisms used by NiV to counteract host immune defense responses have been described, all of the processes that take place in cells ...
Cecilia Alejandra Vázquez, Lina Widerspick, Roland Thuenauer, Carola Schneider, Rudolph Reimer, Pedro Neira, Catherine Olal, Michelle Heung, Linda Niemetz, Philip Lawrence, Indre Kucinskaite-Kodze, Lars Redecke, Beatriz Escudero-Pérez   +12 more
doaj   +1 more source

Phytochemical Analysis and Pharmaceutical Applications of Monoterpenoids Present in the Essential Oil of Boswellia sacra (Omani Luban)

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Due to its intricacy and long‐term usefulness, traditional medicine continues to be practiced in several nations. Among the many medicinal plants found in the Dhofar region of Oman, the aromatic oleo‐gum resin generated by Boswellia sacra, commonly referred to as frankincense, stands out for its medical and commercial significance. Resin‐carrying ducts
Foziya Khan, Luay Rashan, Kuldeep Singh
wiley   +1 more source

National Seroprevalence and Risk Factors of Bluetongue Virus in Domestic Ruminants of Peru

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Bluetongue (BT) is a viral infection caused by the bluetongue virus (BTV) that affects domestic and wild ruminants worldwide. It is primarily transmitted by Culicoides spp. midges, and its infection is highly prevalent across temperate and tropical regions.
Dennis A. Navarro-Mamani, Jessica Jurado, Ana Vargas-Calla, Kevin Ponce, Tyler Sherman, Yari Zarate, César A. Murga-Moreno, Ibelice Perez, Ruben Villacaqui, Miguel Ara, Pedro Ortiz, Hermelinda Rivera, Christie E. Mayo, Fedor Korennoy   +13 more
wiley   +1 more source

Spatial expansions and travelling waves of rabies in vampire bats [PDF]

, 2016
A major obstacle to anticipating the cross-species transmission of zoonotic diseases and developing novel strategies for their control is the scarcity of data informing how these pathogens circulate within natural reservoir populations.
Benavides, Julio A., Streicker, Daniel, Valderrama, William   +2 more
core   +1 more source

Tolerance has its limits: how the thymus copes with infection [PDF]

, 2013
The thymus is required for T cell differentiation; a process that depends on which antigens are encountered by thymocytes, the environment surrounding the differentiating cells, and the thymic architecture.
AbuAttieh, Ahmed, Auwaerter, Baroni, Borges, Brilot, Brito, Calabro, Calello, Cardenas Palomo, Cavalcante, Cavalcante, Chen, Claudia Nobrega, Cláudio Nunes-Alves, Corbeau, Cotta-de-Almeida, Deobagkar-Lele, Dooley, Douek, Feldman, Francelin, Freitas, Gameiro, Godfraind, Gossmann, Gray, Hale, Ho Tsong Fang, Huldt, Islam, Jamieson, Korostoff, Lamontagne, Margarida Correia-Neves, Martin, Mendes-da-Cruz, Mendes-da-Cruz, Milich, Miller, Mocarski, Nascimbeni, Nascimbeni, Nobrega, Nobrega, Nobrega, Ozeki, Pellegrini, Perez, Prabhu, Proietto, Raviola, Reiley, Ross, Rozmyslowicz, Samuel M. Behar, Sauce, Savino, Savino, Schmitt, Song, Sotomayor, Stanley, Starr, Stevens, Su, Sutton, Takahama, Tsuji, Uldrich, Valentin, Vezys, Vogel, Weiss, Wolf, Wykrzykowska, Yoshimura, Yoshimura   +77 more
core   +1 more source