Results 41 to 50 of about 2,897,916 (227)

Junin virus structural proteins [PDF]

open access: yesJournal of Virology, 1977
Polyacrylamide gel electrophoresis of purified Junin virus revealed six distinct structural polypeptides, two major and four minor ones. Four of these polypeptides appeared to be covalently linked with carbohydrate. The molecular weights of the six proteins, estimated by coelectrophoresis with marker proteins, ranged from 25,000 to 91,000.
Z M, De Martínez Segovia, M I, De Mitri
openaire   +2 more sources

A Narrative Review on Argentine Hemorrhagic Fever: Junin Virus (JUNV)

open access: yesJournal of Clinical Immunology & Microbiology, 2023
Epidemic cases of Argentine hemorrhagic fever (also known as AHF) have been associated with the Junin virus, also known as JUNV, ever since the 1950s. The JUNV arenavirus is endemic to the countries of the New World.
Sadia Afrin
semanticscholar   +1 more source

The Estimation of Efficacy of Nonspecific Medications Against Hemorrhagic Fevers Caused by Arenaviruses

open access: yesАнтибиотики и Химиотерапия, 2023
The article presents an analysis of studies assessing the effectiveness of new nonspecific medications against hemorrhagic fevers caused by arenaviruses.
Т. Е. Sizikova   +2 more
doaj   +1 more source

The entry of Junin virus into Vero cells [PDF]

open access: yesArchives of Virology, 1994
The entry mechanism of Junin virus (JV) into Vero cells was studied analyzing the effect of lysosomotropic compounds and acid pH on JV infection. Ammonium chloride, amantadine, chlorpheniramine and procaine inhibited JV production. The action of ammonium chloride was exerted at early times of infection.
Castilla, V.   +3 more
openaire   +2 more sources

Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia

open access: yesVirulence, 2023
Mammarenaviruses, a genus of the family Arenaviridae, are capable of infecting mammals and are primarily found in rodent reservoirs worldwide. Mammarenaviruses can be transmitted to humans through contact with infected rodents, and though infection is ...
Brigitte Flannery   +2 more
doaj   +1 more source

Luminescent reporter cells enable the identification of broad‐spectrum antivirals against emerging viruses

open access: yesJournal of Medical Virology, Volume 95, Issue 11, November 2023., 2023
Abstract The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and hemorrhagic diseases, respectively. The production of infectious particles of both viruses and virus spread in tissues requires cleavage of surface glycoproteins (GPs) by host proprotein convertases (PCs).
Karin Löw   +10 more
wiley   +1 more source

The knowns and unknowns of cardiac autoimmunity in viral myocarditis

open access: yesReviews in Medical Virology, Volume 33, Issue 6, November 2023., 2023
Abstract Myocarditis can result from various infectious and non‐infectious causes that can lead to dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are commonly suspected. But the challenge is our inability to demonstrate infectious viral particles during clinical presentations, partly because by that point, the ...
Kiruthiga Mone, Jay Reddy
wiley   +1 more source

Standardization of an ELISA test using a recombinant nucleoprotein from the Junin virus as the antigen and serological screening for arenavirus among the population of Nova Xavantina, State of Mato Grosso Padronização de um teste de ELISA utilizando a nucleoproteína recombinante de vírus Junin como antígeno e triagem sorológica para Arenavírus na população de Nova Xavantina, Estado do Mato Grosso

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: Arenavirus hemorrhagic fever is a severe emerging disease. METHODS: Considering that the levels of antibodies against arenavirus in the Brazilian population are completely unknown, we have standardized an ELISA test for detecting IgG ...
Alex Martins Machado   +5 more
doaj   +1 more source

In vitro infection of murine macrophages with Junin virus [PDF]

open access: yesInfection and Immunity, 1982
Mouse peritoneal macrophages were successfully infected with two strains of Junin virus producing high titers with no apparent cell damage. Infected cultures survived longer than noninfected cultures. The pattern of virus release suggested a persistent infection.
P H, González   +3 more
openaire   +2 more sources

Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies

open access: yesmBio, 2022
Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng   +9 more
doaj   +1 more source

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