Results 41 to 50 of about 5,647 (215)

The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. [PDF]

, 2018
Feline infectious peritonitis (FIP) is a common and highly lethal coronavirus disease of domestic cats. Recent studies of diseases caused by several RNA viruses in people and other species indicate that antiviral therapy may be effective against FIP in ...
Bauer, K, Eckstrand, C, Liepnieks, M, Murakami, E, Murphy, BG, Park, Y, Pedersen, NC, Perron, M   +7 more
core   +1 more source

Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. [PDF]

PLoS Neglected Tropical Diseases, 2011
Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic fever syndromes Lassa fever and Argentine hemorrhagic fever, respectively.
Michelle Mendenhall, Andrew Russell, Donald F Smee, Jeffery O Hall, Ramona Skirpstunas, Yousuke Furuta, Brian B Gowen   +6 more
doaj   +1 more source

Urinary virome perturbations in kidney transplantation [PDF]

, 2018
The human microbiome is important for health and plays a role in essential metabolic functions and protection from certain pathogens. Conversely, dysbiosis of the microbiome is seen in the context of various diseases. Recent studies have highlighted that
Carrie D. Nicora, Kristin Burnum-Johnson, Minnie M. Sarwal, Neil Mercer, Sharvin Nandoe, Sharvin Nandoe, Tara K. Sigdel, Wei-Jun Qian   +7 more
core   +5 more sources

Junin Virus Infection in Genetically Athymic Mice

Intervirology, 1983
The progression of Junin virus infection was studied in congenitally athymic mice. Immunocompetent littermates were used as infected controls. As expected, the latter developed lethal encephalitis, with viremia and considerable viral replication in the brain.
M C, Weissenbacher, M A, Calello, C J, Quintans, H, Panisse, N M, Woyskowsky, V H, Zannoli   +5 more
openaire   +2 more sources

Interaction of silver nanoparticles with Tacaribe virus [PDF]

, 2010
Background Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. Recently they received attention when it was shown that 10 nm silver nanoparticles were bactericidal, which is ...
Janice L Speshock, Richard C Murdock, Laura K Braydich-Stolle, Amanda M Schrand, Saber M Hussain   +4 more
core   +2 more sources

A hTfR1 Receptor-Specific VHH Antibody Neutralizes Pseudoviruses Expressing Glycoproteins from Junín and Machupo Viruses

Viruses
The Junín virus (JUNV) is one of the New World arenaviruses that cause severe hemorrhagic fever. Human transferrin receptor 1 (hTfR1) has been identified as the main receptor for JUNV for virus entry into host cells.
Qinglin Kang, Gege Li, Yan Wu, Shaoyan Wang, Zhengshan Chen, Xiaodong Zai, Xiaoyan Pan, Rong Wang, Jiansheng Lu, Peng Du, Zhixin Yang, Xiangyang Chi, Gengfu Xiao, Junjie Xu   +13 more
doaj   +1 more source

Human Hemorrhagic Fever Causing Arenaviruses: Molecular Mechanisms Contributing to Virus Virulence and Disease Pathogenesis

Pathogens, 2015
Arenaviruses include multiple human pathogens ranging from the low-risk lymphocytic choriomeningitis virus (LCMV) to highly virulent hemorrhagic fever (HF) causing viruses such as Lassa (LASV), Junin (JUNV), Machupo (MACV), Lujo (LUJV), Sabia (SABV ...
Junjie Shao, Yuying Liang, Hinh Ly
doaj   +1 more source

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression [PDF]

, 2017
Immune-mediated effector molecules can limit cancer growth, but lack of sustained immune activation in the tumour microenvironment restricts antitumour immunity.
Gassa, Asmae, Helfrich, Iris, Kalkavan, Halime, Kasper, Stefan, Lohning, Max, Pandyra, Aleksandra A., Sharma, Piyush, Virchow, Isabel, Willimsky, Gerald   +8 more
core   +1 more source

Protection Against Junin Virus by Immunization with Live Tacaribe Virus

Experimental Biology and Medicine, 1965
SummaryAdult guinea pigs immunized with the live Tacaribe virus are able to resist challenge with a large dose of Junin virus to which they are normally susceptible. Sera from the Tacaribe virus-immunized guinea pigs contain abundant homologous antibody demonstrable by both complement-fixation and plaque neutralization tests.
N, TAURASO, A, SHELOKOV
openaire   +2 more sources

Biological Activities of Junin Virus Proteins

Intervirology, 1980
In the Junin virus-infected cell, there is a soluble antigen (SAg), which we have detected by complement fixation.
Maria Ines de Mitri, Zulema M. de Martinez Segovia   +1 more
openaire   +1 more source