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The entry of Junin virus into Vero cells [PDF]
Archives of Virology, 1994 The entry mechanism of Junin virus (JV) into Vero cells was studied analyzing the effect of lysosomotropic compounds and acid pH on JV infection. Ammonium chloride, amantadine, chlorpheniramine and procaine inhibited JV production. The action of ammonium chloride was exerted at early times of infection.
Castilla, V. +3 more
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Virulence, 2023 Mammarenaviruses, a genus of the family Arenaviridae, are capable of infecting mammals and are primarily found in rodent reservoirs worldwide. Mammarenaviruses can be transmitted to humans through contact with infected rodents, and though infection is ...
Brigitte Flannery +2 more
doaj +1 more source
The Virus–Host Interplay in Junín Mammarenavirus Infection
Viruses, 2022 Junín virus (JUNV) belongs to the Arenaviridae family and is the causative agent of Argentine hemorrhagic fever (AHF), a severe human disease endemic to agricultural areas in Argentina.
Giovanna Lucrecia Gallo +2 more
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Journal of Medical Virology, Volume 95, Issue 11, November 2023., 2023 Abstract The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and hemorrhagic diseases, respectively. The production of infectious particles of both viruses and virus spread in tissues requires cleavage of surface glycoproteins (GPs) by host proprotein convertases (PCs).
Karin Löw +10 more
wiley +1 more source
The knowns and unknowns of cardiac autoimmunity in viral myocarditis
Reviews in Medical Virology, Volume 33, Issue 6, November 2023., 2023 Abstract Myocarditis can result from various infectious and non‐infectious causes that can lead to dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are commonly suspected. But the challenge is our inability to demonstrate infectious viral particles during clinical presentations, partly because by that point, the ...
Kiruthiga Mone, Jay Reddy
wiley +1 more source
Surface layer proteins in species of the family Lactobacillaceae
Microbial Biotechnology, Volume 16, Issue 6, Page 1232-1249, June 2023., 2023 Manuscript is focus on the prediction of slp genes within the Lactobacillaceae family and interconnection between the two different modular SLP domain organizations of the new reclassified genera. SLP applications are reviewed regarding heterologous display, pathogen exclusion, immunostimulation, and metal binding. Abstract The S‐layer or surface layer
M. Mercedes Palomino +5 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2010 INTRODUCTION: Arenavirus hemorrhagic fever is a severe emerging disease. METHODS: Considering that the levels of antibodies against arenavirus in the Brazilian population are completely unknown, we have standardized an ELISA test for detecting IgG ...
Alex Martins Machado +5 more
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mBio, 2022 Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng +9 more
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Structural basis for recognition and regulation of arenavirus polymerase L by Z protein
Nature Communications, 2021 Junin virus (JUNV) causes Argentine hemorrhagic fever and encodes the large protein (L) of the RNA dependent RNA polymerase (RdRp) and its regulator, the matrix zinc-binding protein (Z).
Huiling Kang +8 more
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Replication of Junin Virus in the Presence of Tunicamycin
Intervirology, 1984 In the presence of tunicamycin (TM), an antibiotic which inhibits glycosylation, Junin virus-infected cells released 70% as much virus as control cultures, as measured by [35S]-methionine appearing in a sucrose gradient virus particle fraction. In this same fraction, the incorporation of [14C]-glucosamine was inhibited 85% by TM, accompanied by a ...
P J, Padula, Z M, de Martínez Segovia
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