Junín Virus Pathogenesis and Virus Replication [PDF]
Viruses, 2012 Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina.
Olga Kolokoltsova +6 more
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Development of a Reverse Genetic System to Generate Recombinant Chimeric Tacaribe Virus that Expresses Junín Virus Glycoproteins. [PDF]
Pathogens, 2020 Mammarenaviruses are enveloped and segmented negative-stranded RNA viruses that comprise several pathogenic members associated with severe human hemorrhagic fevers. Tacaribe virus (TCRV) is the prototype for the New World group of mammarenaviruses and is
Foscaldi S +5 more
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Guinea Pig Transferrin Receptor 1 Mediates Cellular Entry of Junín Virus and Other Pathogenic New World Arenaviruses. [PDF]
J Virol, 2020 JUNV is one of five known NWAs that cause viral hemorrhagic fever in humans. Countermeasures against JUNV infection are limited to immunization with the Candid#1 vaccine and immune plasma, which are available only in Argentina.
Hickerson BT +4 more
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Junín Virus Promotes Autophagy To Facilitate the Virus Life Cycle. [PDF]
J Virol, 2019 Mammalian arenaviruses are zoonotic viruses that cause asymptomatic and persistent infections in their rodent hosts but may produce severe and lethal hemorrhagic fevers in humans.
Roldán JS +3 more
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RIG-I enhanced interferon independent apoptosis upon Junin virus infection. [PDF]
PLoS ONE, 2014 Junin virus (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF), a human disease with a high case-fatality rate. It is widely accepted that arenaviral infections, including JUNV infections, are generally non-cytopathic. In contrast, here
Olga A Kolokoltsova +10 more
doaj +2 more sources
The Virus–Host Interplay in Junín Mammarenavirus Infection
Viruses, 2022 Junín virus (JUNV) belongs to the Arenaviridae family and is the causative agent of Argentine hemorrhagic fever (AHF), a severe human disease endemic to agricultural areas in Argentina.
Giovanna Lucrecia Gallo +2 more
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Neutralization of Junín virus by single domain antibodies targeted against the nucleoprotein. [PDF]
Sci Rep, 2018 The syndrome viral haemorrhagic fever (VHF) designates a broad range of diseases that are caused by different viruses including members of the family Arenaviridae. Prophylaxis for Argentine Haemorrhagic Fever (AHF), caused by the arenavirus Junín (JUNV),
Linero F +5 more
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Antigen vehiculization particles based on the Z protein of Junin virus [PDF]
BMC Biotechnology, 2012 Background Arenavirus matrix protein Z plays an important role in virus budding and is able to generate enveloped virus-like-particles (VLPs) in absence of any other viral proteins.
Borio Cristina S +6 more
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Effective Population Size Differences in Calomys musculinus, the Host of Junín Virus: Their Relationship with the Epidemiological History of Argentine Hemorrhagic Fever. [PDF]
Am J Trop Med Hyg, 2018 Argentine hemorrhagic fever (AHF) is a serious endemic disease in Argentina, produced by Junín virus, whose host is the Sigmodontinae rodent Calomys musculinus.
Chiappero MB +5 more
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Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy. [PDF]
Antiviral Res, 2017 A collection of Old and New World arenaviruses are etiologic agents of viral hemorrhagic fever, a syndrome that features hematologic abnormalities, vascular leak, hypovolemia, and multi-organ failure. Treatment is limited to ribavirin for Lassa fever and
Gowen BB +7 more
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