Results 91 to 100 of about 2,707,204 (292)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The uneven foundations of a just transition for workers: a UK perspective
Frontiers in ClimateAssessments of the workforce impacts of net zero transitions have largely focussed on job losses, gains and net changes for a particular industry, sector or state.
Dave Reay
doaj +1 more source
, 2010 We consider an inhomogeneous quantum phase transition across a multicritical point of the XY quantum spin chain. This is an example of a Lifshitz transition with a dynamical exponent z = 2. Just like in the case z = 1 considered in New J. Phys.
Canovi E +16 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Just transition in the northwest territories: Insights and values from indigenous and non-indigenous northerners. [PDF]
Heliyon, 2023 Amber C, Agrawal S, Zoe C.
europepmc +1 more source
A Proposal for Altering the Unification Scale in String Theory
, 2005 An ensemble of short open strings in equilibrium with the heat bath provided by the Euclidean worldvolume of a stack of Dbranes undergoes a thermal phase transition to a long string phase. The transition temperature is just below the string scale.
Chaudhuri +25 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
How do past global experiences of coal phase-out inform China's domestic approach to a just transition? [PDF]
Sustain Sci, 2023 Sharma V +4 more
europepmc +1 more source
Localization and adiabatic pumping in a generalized Aubry-Andr\'e-Harper model
, 2014 A generalization of the Aubry-Andr\'e-Harper (AAH) model is developed, containing a tunable phase shift between on-site and off-diagonal modulations. A localization transition can be induced by varying just this phase, keeping all other model parameters ...
Chong, Y. D. +2 more
core +1 more source