Results 21 to 30 of about 18,031 (200)

Dysregulation of complement factor H in juvenile-onset systemic lupus erythematosus patients. [PDF]

Arch Rheumatol, 2022
Objectives: This study aims to evaluate the expression pattern of factor H in peripheral blood and the frequency of factor H autoantibodies in plasma of juvenile-onset systemic lupus erythematosus (jSLE) patients compared to healthy controls. Patients and methods: Between March 2019 and October 2019, a total of 30 healthy individuals (3 males, 27 ...
Eissa E, Morcos B, Dorgham D, Kholoussi N.   +3 more
europepmc   +4 more sources

Juvenile systemic lupus erythematosus presenting only as nonscarring alopecia

Indian Journal of Paediatric Dermatology, 2022
Juvenile onset systemic lupus erythematosus (JSLE) is a rare multisystem, autoimmune disorder. Alopecia in SLE generally follows a pre-established disease with systemic symptoms. A 13-year-old girl presented with sudden hair loss over the vertex of scalp
N M Vinitha, Reena Rai, G Uma Maheswari
doaj   +1 more source

Rituximab therapy for juvenile-onset systemic lupus erythematosus [PDF]

Pediatric Nephrology, 2007
Rituximab (RTX), an anti-CD20 monoclonal antibody, has been proposed for use in the therapy of systemic lupus erythematosus (SLE). We present the initial long-term experience of the safety and efficacy of rituximab for treatment of SLE in children.
Nwobi, Obioma, Abitbol, Carolyn L., Chandar, Jayanthi, Seeherunvong, Wacharee, Zilleruelo, Gastón   +4 more
openaire   +2 more sources

Juvenile-onset multifocal osteonecrosis in systemic lupus erythematosus

Medicine, 2021
Abstract Rationale: Osteonecrosis (ON) is a devastating illness that leads to bone ischemia and potential joint destruction. Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with multi-system involvement which is closely associated with occurrence of ON.
Jin, Wenyuan, Yang, Xinghui, Lu, Meiping
openaire   +2 more sources

Macrophage activation syndrome triggered by systemic lupus erythematosus flare: successful treatment with a combination of dexamethasone sodium phosphate, intravenous immunoglobulin, and cyclosporine: a case report

Journal of Medical Case Reports, 2021
Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s disease
Wesam Gouda, Faisal Alsaqabi, Abdelhfeez Moshrif, Awad S. Abbas, Tarek M. Abdel-Aziz, Md Asiful Islam   +5 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]

, 2015
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario, Feola, Aldo, Granata, Guido, Granata, Massimo, Stifano, Giuseppina   +4 more
core   +4 more sources

Histopathology of the gut in rheumatic diseases [PDF]

, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F., Ferrante A., Guggino G., Macaluso F., Rizzo A.   +4 more
core   +1 more source

Differences in disease phenotype and severity in SLE across age groups [PDF]

, 2016
OBJECTIVES: Significant differences have been reported in disease phenotype and severity of systemic lupus erythematosus (SLE) presenting in different age groups. Most indicate a more severe phenotype in juvenile-onset SLE (JSLE). There have been limited
Ambrose, N, Beresford, MW, Galloway, J, Grp, UKJSLE Study, Ionnoau, Y, Isenberg, DA, Morgan, TA   +6 more
core   +1 more source

Inadequate dietary intake of children and adolescents with juvenile idiopathic arthritis and systemic lupus erythematosus [PDF]

, 2009
OBJECTIVES: To evaluate the dietary intake of children and adolescents with juvenile idiopathic arthritis (JIA) and juvenile systemic lupus erythematosus (JSLE) using a 24-hour diet recall and relating it to the patients clinical and anthropometric ...
Caetano, Michelle Caetano, Hilário, Maria Odete Esteves, Ortiz, Thaís Tobaruela, Sarni, Roseli Oselka Saccardo, Silva, Simone Guerra Lopes, Souza, Fabíola Isabel Suano, Terreri, Maria Teresa Ramos Ascensão   +6 more
core   +3 more sources