Results 111 to 120 of about 11,948,174 (351)

Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after infection [PDF]

, 2008
Background Sex differences have been described in a number of pulmonary diseases. However, the impact of ozone exposure followed by pneumonia infection on sex-related survival and macrophage function have not been reported.
HC Nielsen, RH Perelman, CF Caracta, F Gutierrez, CJ Gannon, C Guilbault, SC FitzSimmons, DM Underhill, DS Phelps, AM LeVine, AN Mikerov, JL Peel, HM Boezen, JW Hollingsworth, S Becker, S Miller, B Muller, FJ Kelly, TM Umstead, B Janic, G Wang, G Wang, W Huang, AN Mikerov, MI Gilmour, R Haque, AN Mikerov, I Annesi-Maesano, CE Baleeiro, MA Carey, AL Yancey, WB Baine, G Mostafa, DP Kofteridis, V Kaplan, LS Van Winkle, MB Bailie, JA Spitzer, JA Spitzer, M Tanabe, P Markart, AD O'Brien, N De Bont, M Osman, M Erikoglu, JW Card, C Reinhard, GD Massaro   +47 more
core   +2 more sources

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Differential between multi-drug resistance pattern of extended spectrum b- Lactamases producing E. coli and K. pneumoniae [PDF]

, 2014
The current study aimed to determine the prevalence of Extended-Spectrum b-Lactamases (ESBLs) in Escherichia coli (E. coli) and Klebsiella pneumoniae (K.
Aboualigalehdari, Elham, Awang Hamat, Rukman, Ghafourian, Sobhan, Hosseini, Shiva, Maleki, Abbas, Mohebi, Reza, Sadeghifard, Nourkhoda, Sekawi, Zamberi, Soheili, Sara   +8 more
core   +1 more source

Detection of VIM-1 and IMP-1 genes in Klebsiella pneumoniae and relationship with biofilm formation [PDF]

, 2018
Klebsiella pneumoniae is an important human pathogen that is considered in recent years due to nosocomial infections resistant to treatment as well as the ability to form biofilms particularly in patients with urinary tract infection in ICU or hospital ...
Javadi, A., Khodadadian, R., Khorshidi, A., Rahdar, H.A., Safari, M.   +4 more
core   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Prevalence, Virulence, and Pathogenic Mechanisms of Mastitis-Associated Klebsiella pneumoniae in Herds and Phage-Based Control Strategies

Veterinary Sciences
Klebsiella pneumoniae (K. pneumoniae) is an opportunistic and environmental mastitis pathogen prevalent in dairy herds worldwide. Owing to their genetic and genomic diversity, K.
Wenhui Li, Jianwei Wang, Yangsen Wang, Pu Yan, Zhihua Ren, Tong Fu   +5 more
doaj   +1 more source

Carbapenem resistance profile amongst Escherichia coli and Klebsiella pneumoniae in a tertiary care hospital in Ahmednagar, Maharashtra [PDF]

, 2014
Introduction: Carbapenem-resistant Enterobacteriaceae (CRE), specially three species of the Enterobacteriaceae family, the Klebsiella, Enterobacter and Escherichia have developed resistance to a group of antibiotics called “Carbapenems”, which are ...
Shraddha Prasad Gunjal, Prasad Niranjan Gunjal, Nagaraju Vanaparthi, Kher Sudheer
core   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Mobile genetic elements encoding antibiotic resistance genes and virulence genes in Klebsiella pneumoniae: important pathways for the acquisition of virulence and resistance

Frontiers in Microbiology
Klebsiella pneumoniae is an opportunistic pathogen primarily associated with nosocomial infections, characterized by a propensity for multi-drug resistance and the potential evolution into hypervirulent strains.
Bin Han, Bin Han, Bin Han, Bin Han, Chunlin Feng, Chunlin Feng, Chunlin Feng, Yuan Jiang, Yuan Jiang, Yuan Jiang, Caihong Ye, Caihong Ye, Caihong Ye, Yueshuai Wei, Yueshuai Wei, Yueshuai Wei, Jinbo Liu, Jinbo Liu, Jinbo Liu, Jinbo Liu, Zhangrui Zeng, Zhangrui Zeng, Zhangrui Zeng   +22 more
doaj   +1 more source