Results 121 to 130 of about 11,948,174 (351)

Whole-Genome Sequencing of Human Clinical Klebsiella pneumoniae Isolates Reveals Misidentification and Misunderstandings of Klebsiella pneumoniae, Klebsiella variicola, and Klebsiella quasipneumoniae

mSphere, 2017
Klebsiella pneumoniae is a major threat to public health, causing significant morbidity and mortality worldwide. The emergence of highly drug-resistant strains is particularly concerning. There has been a recognition and division of Klebsiella pneumoniae
S. Wesley Long, Sarah E. Linson, Matthew Ojeda Saavedra, Concepcion Cantu, James J. Davis, Thomas Brettin, Randall J. Olsen   +6 more
doaj   +1 more source

Fingolimod synergizes and reverses K. pneumoniae resistance to colistin

Frontiers in Microbiology
Klebsiella pneumoniae (K. pneumoniae) infection and the rapid spread of multi-drug resistant (MDR) bacteria pose a serious threat to global healthcare. Polymyxin E (colistin), a group of cationic antimicrobial polypeptides, is currently one of the last resort treatment options against carbapenem-resistant Gram-negative pathogens.
Xiang Geng, Zhen-Dong Zhang, Yu-Xi Li, Ruo-Chen Hao, Ya-Jun Yang, Xi-Wang Liu, Jian-Yong Li   +6 more
openaire   +3 more sources

Detection of acrA, acrB, aac(6′)-Ib-cr, and qepA genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae [PDF]

, 2016
Background: The distribution of drug resistance among clinical isolates of Escherichia coli and Klebsiella pneumoniae has limited the therapeutic options. The aim of this study was to report the prevalence of quinolone resistance genes among E.
Bahramian, Aghil, Eslami, Gita, Goudarzi, Hossein, Goudarzi, Mehdi, Hashemi, Ali, Heidary, Mohsen, Omrani, Vahid Fallah   +6 more
core   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Elevated Procalcitonin Levels in Pediatric Severe Bacterial Pneumonia Caused by Klebsiella pneumoniae

MCBS (Molecular and Cellular Biomedical Sciences)
Background: Klebsiella pneumoniae is a major pathogen in pediatric pneumonia. Procalcitonin (PCT) distinguishes between Gram positive and Gram negative infections but lacks data on K.
Tri Kusumawijayanti, David Anggara Putra, Yulidar Hafidh, Ismiranti Andarini   +3 more
doaj   +1 more source

Fecal Carriage of ESBL-Producing E. coli and K. pneumoniae in Children in Guinea-Bissau: A Hospital-Based Cross-Sectional Study

PLoS ONE, 2012
Background In recent years, the world has seen a surge in extended-spectrum β-lactamase (ESBL)-producing bacteria. However, data on the dissemination of ESBL-producing Enterobacteriaceae in the community from systematically enrolled study subjects in ...
Joakim Isendahl, A. Turlej-Rogacka, Cristóvão Manjuba, A. Rodrigues, C. Giske, P. Nauclér   +5 more
semanticscholar   +1 more source

Genomic Epidemiology of an Endoscope-Associated Outbreak of Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae

PLOS ONE, 2015
Increased incidence of infections due to Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) was noted among patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) at a single hospital. An epidemiologic investigation identified KPC-Kp and non-KPC-producing, extended-spectrum β-lactamase (ESBL)-producing
Marsh, JW, Krauland, MG, Nelson, JS, Schlackman, JL, Brooks, AM, Pasculle, AW, Shutt, KA, Doi, Y, Querry, AM, Muto, CA, Harrison, LH   +10 more
openaire   +4 more sources

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source

Atypical Klebsiella Species in a Third Level Hospital as Cause of Neonatal Infection [PDF]

, 2018
Aportamos una propuesta para analizar la agresividad de un patógeno en relación a la resistencia y sensibilidad antimicrobianas encontradas.Background: The opportunistic pathogen Klebsiella pneumoniae is one of the main causes of pediatric bacterial ...
CARO GONZALEZ, LUZ MARCELA, CARO GONZALEZ, LUZ MARCELA, CIFUENTES CASTANEDA, DAMIAN DAVID, CIFUENTES CASTANEDA, DAMIAN DAVID, ESPINOZA RIVERA, ILIANA, ESPINOZA RIVERA, ILIANA, MENDIETA ZERON, HUGO, MENDIETA ZERON, HUGO, MORENO PEREZ, MARTIN PABLO ANTONIO, Moreno Pérez, Martín Antonio Pablo, RAMIREZ DURAN, NINFA, RAMIREZ DURAN, NINFA   +11 more
core   +1 more source

Risk Factors for Small‐for‐Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa, Takeo Toshima, Shinji Itoh, Takashi Motomura, Shohei Yoshiya, Norifumi Iseda, Tomoharu Yoshizumi   +6 more
wiley   +1 more source