Results 141 to 150 of about 140,660 (311)

Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran

Iranian Journal of Microbiology, 2014
Background and Objectives: Klebsiella pneumoniae (K. pneumoniae) is an opportunistic microorganism. This study aimed to investigate the presence of magA gene and antimicrobial susceptibility in K. pneumoniae. Materials and Methods: 195 clinical specimens
Hadis Amraie, Pegah Shakib, Samaneh Rouhi, Neda Bakhshandeh, Behnam Zamanzad   +4 more
doaj  

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Molecular epidemiology of ESBL-producing E. coli and K. pneumoniae: establishing virulence clusters

, 2018
Laure Surgers,1,2 Peter Boersma,3 Pierre-Marie Girard,1,4 Audrey Homor,5 Delphine Geneste,2 Guillaume Arlet,2,5 Dominique Decré,2,5 Anders Boyd4 1Infectious Diseases Department, Saint-Antoine Hospital, APHP, Paris, France; 2Sorbonne University ...
Geneste D, Boersma P, Homor A, Decré D, Surgers L, Girard PM, Boyd A, Arlet G   +7 more
core  

Organizational and Functional Principles of the Obligate Respiratory Chain Supercomplex

Journal of the Chinese Chemical Society, EarlyView.
In this review we deliver a comprehensive structural analysis of the actinobacterial respiratory chain supercomplex and discuss the principles underlying the assembly of its supramolecular architecture. ABSTRACT Proton translocating respiratory chain complexes assemble into supramolecular structures in their native cellular environment, yet the ...
Wei‐Chun Kao, Nick Hiatt, Carola Hunte
wiley   +1 more source

K. pneumoniae-induced hepatic apoptosis.

, 2013
Liver sections of PBS-control naïve mice (A), K. pneumoniae-infected naïve mice (B), PBS-control diabetic mice (C), and K. pneumoniae-infected diabetic mice (D) were subjected to TUNEL analysis.
Yi-Chun Lin (480773), Chingju Lin (116735), Min-Chi Lu (213746), Ming-Shiou Jan (112136), Chih-Yang Huang (54970), Hui-Ling Tang (480774), Yi-Chyi Lai (213766), Wea-Lung Lin (480776), Ming-Ko Chiang (213741), Chuan-Mu Chen (180951), Hsu-Chung Liu (480775)   +10 more
core   +1 more source

Utility of a Combined Diagnostic and Severity Scoring System Based on Complete Blood Count and Derived Immune‐Inflammatory Indicators in Children With Mycoplasma pneumoniae Pneumonia

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a simple, low‐cost scoring system using routine complete blood count (CBC) and derived immune‐inflammatory indicators (LYM%, PLT, PCT, and PLT × LYM) for early diagnosis of Mycoplasma pneumoniae pneumonia (MPP) in 1662 children. Age‐stratified analysis confirmed that key indicators remained significantly higher in the pneumonia ...
Quan Liu, Li Wei, Liang Wang, Xing‐Mei Zhu, Hai‐Feng Wang, Ling Ge   +5 more
wiley   +1 more source

Virulence of Klebsiella pneumoniae Serotype K2 Should Not Be Underestimated in K. pneumoniae Liver Abscess [PDF]

Clinical Infectious Diseases, 2007
Chang-Phone, Fung, L K, Siu
openaire   +2 more sources

Klebsiella pneumoniae Peptidoglycan-Associated Lipoprotein and Murein Lipoprotein Contribute to Serum Resistance, Antiphagocytosis, and Proinflammatory Cytokine Stimulation

, 2014
Background. Peptidoglycan-associated lipoprotein (Pal), murein lipoprotein (LppA), and outer membrane protein A (OmpA) are dominant outer membrane proteins (OMPs) that are released by gram-negative bacteria during sepsis.
Hsieh, Pei-Fang;Liu, Ju-Yun;Pan, Yi-Jiun;Wu, Meng-Chuan;Lin, Tzu-Lung;Huang, Yen-Te;Wang, Jin-Town, 林稚容 ;王錦堂   +1 more
core   +1 more source

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source