Results 11 to 20 of about 5,527 (160)

Evaluation of the Effects of the Quaternary Ammonium Silane K21 on Zebrafish Viability, Toxicity, Growth, and Development [PDF]

Biomedicines
Background: The FDA-cleared antimicrobial quaternary ammonium silane K21 is recognized for its antimicrobial properties. This study explored potential applications of the K21 molecule in human health protection, disease prevention, and treatment using ...
Surendra K. Rajpurohit, Devan Anmol S. Manhiani, Ashwin Ajith, Pragya Rajpurohit, Simran Hotwani, Sai Nasanally, Arsha Sreekumar, Keshu Bhat, Aiden Van Derhei, Rohan Pasi, Arishia Mishra, Kirk Kimmerling, Clifton M. Carey   +12 more
doaj   +2 more sources

From an Antimicrobial Agent to a constituent of 3D Printed Heterogenous Scaffolds Stimulating Bone Characteristics: An In-vitro and Animal model evaluation [PDF]

Regenerative Therapy
This paper describes a promising candidate molecule, investigates the pattern of scaffold composition which arises and assesses the effect of the agent on its mechanical properties.
Shahad Ahmed Daood, Martha Then Xin Yi, Nicole Wen Ce Mun, Sharjeel Ilyas, Lee Yin Shien, Oh Jia En, Syed Saad Bin Qasim, Yichen Dai, Galvinderjeet Kaur Grewal, Ng Mei Liit, Gopu Sriram, Malikarjuna Rao Pichika, Kit-Kay Mak, Ranjeet Ajit Bapat, Zeeshan Sheikh, Umer Daood   +15 more
doaj   +2 more sources

A Tutorial on the Development of a Physiologically Inspired PKRO Model for Monoclonal Antibodies. [PDF]

CPT Pharmacometrics Syst Pharmacol
ABSTRACT Modeling and simulations are indispensable tools to describe pharmacokinetics (PK) and pharmacodynamics to support monoclonal antibody (mAb) development. The linear PK of mAbs is commonly described by a 2‐compartment PK model, while the nonlinear PK often observed at low doses is described by target mediated drug disposition (TMDD) models ...
Kapitanov GI, Flowers D, Marcantonio DH, Lezon TR, Apgar JF, Hua F.   +5 more
europepmc   +2 more sources

Unravelling the Programmed Inflammation and Tissue Repair by a Multipotential Antimicrobial K21 Silane [PDF]

International Dental Journal
To examine if a novel antimicrobial silane K21 can alter macrophage polarisation and affect fibroblast proliferation by deciphering the molecular pathways for programmed healing using a combined in vitro and in vivo (animal) burn model.An injectable silane-based antimicrobial aimed to modulate macrophage polarisation was manufactured.
Umer Daood, Muhammad Sharjeel Ilyas, Sehar Bashir, Neelofar Yousuf, Maryam Rashid, Kanwardeep Kaur, Ranjeet Ajit Bapat, Mohammed Nadeem Bijle, Malikarjuna Rao Pichika, Kit-Kay Mak, Shiming Zhang, Zeeshan Sheikh, Abdul Samad Khan, Ove Peters, Jukka P Matinlinna   +14 more
openaire   +4 more sources

Depolymerisation of the Klebsiella pneumoniae Capsular Polysaccharide K21 by Klebsiella Phage K5

International Journal of Molecular Sciences, 2023
Klebsiella pneumoniae is a pathogen associated with various infection types, which often exhibits multiple antibiotic resistance. Phages, or bacterial viruses, have an ability to specifically target and destroy K. pneumoniae, offering a potential means of combatting multidrug-resistant infections.
Anna A. Lukianova, Mikhail M. Shneider, Peter V. Evseev, Mikhail V. Egorov, Anastasiya A. Kasimova, Anna M. Shpirt, Alexander S. Shashkov, Yuriy A. Knirel, Elena S. Kostryukova, Konstantin A. Miroshnikov   +9 more
openaire   +2 more sources

In-vitro evaluation of the effectiveness of polyphenols based strawberry extracts for dental bleaching

Scientific Reports, 2023
To formulate a dental bleaching agent with strawberry extract that has potent bleaching properties and antimicrobial efficacy. Enamel specimens (3 × 3 × 2 mm3) were prepared.
Shivani Kohli, Shekhar Bhatia, Spoorthi Ravi Banavar, Afaf Al-Haddad, Murugesh Kandasamy, Syed Saad Bin Qasim, Mak Kit-Kay, Mallikarjuna Rao Pichika, Umer Daood   +8 more
doaj   +1 more source

Etiological analysis of a small outbreak of gastroenteritis with Vibrio parahaemolyticus infection

Zhongguo shipin weisheng zazhi, 2021
ObjectiveTo investigate the etiology of a small outbreak of gastroenteritis caused by Vibrio parahaemolyticus in Guangzhou, 2017.MethodsSerotype identification, antimicrobial susceptibility test, polymerase chain reaction (PCR) test of virulence genes ...
ZHANG Jing, WANG Anna, TAO Xia, ZHOU Yong, ZHANG Xinqiang, BAI Zhijun   +5 more
doaj   +1 more source

Effect ofLactobacillus plantarumStrain K21 on High-Fat Diet-Fed Obese Mice [PDF]

Evidence-Based Complementary and Alternative Medicine, 2015
Recent studies have demonstrated beneficial effects of specific probiotics on alleviating obesity-related disorders. Here we aimed to identify probiotics with potential antiobesity activity among 88 lactic acid bacterial strains viain vitroscreening assays, and aLactobacillus plantarumstrain K21 was found to harbor abilities required for hydrolyzing ...
Wu, Chien-Chen, Weng, Wei-Lien, Lai, Wen-Lin, Tsai, Hui-Ping, Liu, Wei-Hsien, Lee, Meng-Hwan, Tsai, Ying-Chieh   +6 more
openaire   +2 more sources

Identification of Thalassemia Carrier in Anemic Pregnant Women at Puskesmas Kertapati Palembang: Comparison of Five Erythrocyte Indices

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2021
Anemia is a condition that is almost always found in pregnancy. Although a program of Fe tablets has been introduced during pregnancy, the prevalence of anemia during pregnancy is still high.
Mitayani Purwoko, Eriko Erenkwot
doaj   +1 more source

Should Economists Like Predation or Not?

Competitio, 2020
(A Note on 'Economic Principles of Predatory (Exclusionary Pricing in the US and in the EU - Their (mis) Application in Some Recent Competition Law Cases of the European Community Commission and the Court of First Instance' by Zoltan Bara).
Adam Torok
doaj   +1 more source