Results 171 to 180 of about 40,339 (186)

Reduction of extracellular dehydroascorbic acid by K562 cells

Cell Biochemistry and Function, 1996
AbstractK562 erythroleukaemic cells produced ascorbate when incubated with dehydroascorbic acid. The reduction depended on the number of cells and on the concentration of dehydroascorbic acid. The observed rate consists of a high affinity (apparent) Km 7 μM, Vmax 3·25 pmol min−1 (106 cells)−1 and a low affinity component, which was non‐saturable up to ...
E, Schweinzer, Y, Mao, P, Krajnik, N, Getoff, H, Goldenberg   +4 more
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Spontaneous Cytotoxic Earthworm Leukocytes Kill K562 Tumor Cells

Zoological Science, 1995
Earthworm coelomocytes may act as effector cells which destroy targets in vitro. In a 51Cr release assay, Lumbricus coelomocyte effectors showed lytic activities of 3-14% against K562 human tumor cells when incubated 1-4 hr at 23 degrees C or 37 degrees C. Cytotoxicity was correlated with effector: target ratio.
M M, Suzuki, E L, Cooper
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Persistent infection of K562 cells by encephalomyocarditis virus

Journal of Virology, 1990
Infection of human erythroleukemic K562 cells by encephalomyocarditis virus readily resulted in establishment of persistently infected cultures. In contrast to the usual typical lytic infection by encephalomyocarditis virus, in which trypan blue staining of cells reaches close to 100% by about 15 h postinfection, K562 cell cultures required 3 to 4 days
I U, Pardoe, K K, Grewal, M P, Baldeh, J, Hamid, A T, Burness   +4 more
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Increased cation transport inmdr1-gene-expressing K562 cells

Cancer Chemotherapy and Pharmacology, 1995
Cation-transport properties were compared in a human leukemic cell line (K562) and its vincristine-selected, mdr1-gene-expressing sublines (K562/Vcr30 and K562/Vcr150) by the capacity of the cells to accumulate the potassium analogue thallium (201Tl). Determination of the time course of thallium accumulation in the absence and presence of ouabain, an ...
T, Brismar, A, Gruber, C, Peterson
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K562 cells: a source for embryonic globin chains

Journal of Chromatography B: Biomedical Sciences and Applications, 1991
A combination of DEAE-cellulose chromatography and reversed-phase high-performance liquid chromatography (HPLC) has been used to devise a method for generating large quantities of embryonic as well as fetal globin chains. The identity of these globin chains was further confirmed by their tryptic peptide mapping. This technique could, therefore, provide
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[Knock-down of CARMA1 in K562 cells inhibits the invasion and metastasis of K562 cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2014
To study the effects of caspase recruitment domain membrane-associated guanylate kinase protein 1 (CARMA1) knock-down using RNAi technology on cell proliferation, colony forming, invasion and metastasis of the K562 cells.K562 cells with stably-silenced CARMA1 gene was constructed by lentivirus-mediated RNAi technology.
Fang, Liu, Lingyan, Wang, Jieyu, Li, Shuping, Chen, Yunbin, Ye   +4 more
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Anti-cancer effects of deguelin on human leukemia K562 and K562/ADM cells In Vitro

Journal of Huazhong University of Science and Technology, 2007
In order to investigate the anti-cancer effects of deguelin and on K562 and K562/ADM cells in vitro and the underlying molecular mechanism and compare the cytotoxicity of deguelin on K562, K562/ADM cells and human peripheral blood mononuclear cells (PBMCs). The effects of deguelin on cell proliferation were assessed by MTT assay.
Qiuling, Wu, Yan, Chen, Hongli, Liu, Jing, He   +3 more
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Inhibition of human NK cell cytotoxicity against K562 cells with glycopeptides from K562 plasma membranes.

Journal of clinical & laboratory immunology, 1985
Human Natural Killer (NK) cell activity against K562 target cells has previously been shown to be inhibited by certain monosaccharides and glycoproteins in a specific fashion. Glycopeptides have been prepared from the isolated plasma membranes of cultured K562 cells by extensive pronase digestion and fractionated by lectin affinity chromatography. Nine
J M, Decker, A, Hinson, E W, Ades
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Cyanine Dyes as Protectors of K562 Cells from Photosensitized Cell Damage†

Photochemistry and Photobiology, 2000
Several cyanine dyes were found to protect K562 leukemia cells against toxicity mediated by cis-di(4-sulfonatophenyl)diphenylporphine (TPPS2) and light. Most cyanine dyes derived from dimethylindole were better photoprotectors than cyanine dyes with other structures.
P D, Sima, J R, Kanofsky
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[Deferoxamine induces apoptosis of K562 cells].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2011
To study the molecular mechanism of apoptosis of leukemic cells (K562 cells) induced by iron chelating agent deferoxamine (DFO).The exponentially growing K562 cells were used (1×10(6)/mL) in this study. The K562 cells were treated with different concentrations of DFO (10, 50 and 100 mmol/L), DFO+FeCl3 (10 μmol/L each) or normal saline (blank control ...
Guo-Cun, Jia, You-Cai, Tang, Feng-Yi, Li, Qing-Kui, Liao   +3 more
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