Results 161 to 170 of about 10,434 (197)

Expression of C antigen in transduced K562 cells

Transfusion, 2001
BACKGROUND: The Rh blood group system is involved in HDN and transfusion reactions. A retrovirus‐expression system was previously used to show that polypeptides carrying the Rh blood group antigens are encoded by the RHD and RHCE genes. This study investigated the structure of the C antigen.STUDY DESIGN AND METHODS: K562 cells were transduced with full‐
J S, Smythe, D J, Anstee
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Characterization of a particulate pathway for copper in K562 cells

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1994
More than half of the 67Cu recovered from K562 cells following a brief incubation with 67Cu-ceruloplasmin was recovered in particulate fractions of the cell. The fractions in Percoll had densities that ranged between 1.040 and 1.060 g/dl. In as early as 5 min, two fractions, densities of 1.051 and 1.056, respectively, were discernible.
L A, Davidson, S L, McOrmond, E D, Harris   +2 more
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Glycosphingolipids of K562 cells: A chemical and immunological analysis

International Journal of Cancer, 1981
AbstractThe K562 cell line, which was established from a patient with chronic myeloid leukemia in blast crisis, was thought to be myeloid, but recent data indicate that it is an undifferentiated erythroid cell line. We have found that the glycosphingolipid content of these cells differs considerably from that of mature erythrocytes ...
A, Suzuki, R A, Karol, S K, Kundu, D M, Marcus   +3 more
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Reduction of extracellular dehydroascorbic acid by K562 cells

Cell Biochemistry and Function, 1996
AbstractK562 erythroleukaemic cells produced ascorbate when incubated with dehydroascorbic acid. The reduction depended on the number of cells and on the concentration of dehydroascorbic acid. The observed rate consists of a high affinity (apparent) Km 7 μM, Vmax 3·25 pmol min−1 (106 cells)−1 and a low affinity component, which was non‐saturable up to ...
E, Schweinzer, Y, Mao, P, Krajnik, N, Getoff, H, Goldenberg   +4 more
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Induction of apoptosis in K562 cells by jolkinolide B

Canadian Journal of Physiology and Pharmacology, 2006
Jolkinolide B, a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud, has various biological and pharmacological properties. In this study, the cytotoxicity of highly purified jolkinolide B was tested in human chronic myeloid leukemia (K562) and 2 other cell lines (human esophageal carcinoma Eca-109 and human hepatoma HepG2 ...
Huiying, Luo, Aiqin, Wang
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[Knock-down of CARMA1 in K562 cells inhibits the invasion and metastasis of K562 cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2014
To study the effects of caspase recruitment domain membrane-associated guanylate kinase protein 1 (CARMA1) knock-down using RNAi technology on cell proliferation, colony forming, invasion and metastasis of the K562 cells.K562 cells with stably-silenced CARMA1 gene was constructed by lentivirus-mediated RNAi technology.
Fang, Liu, Lingyan, Wang, Jieyu, Li, Shuping, Chen, Yunbin, Ye   +4 more
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Photodynamic Action of Benzo[a]pyrene in K562 Cells

Photochemistry and Photobiology, 2007
AbstractBenzo[a]pyrene (BaP) is ubiquitously distributed in the environment, being considered the most phototoxic element among polycyclic aromatic hydrocarbon (PAHs). In presence of oxygen, PAHs can act as a photosensitizer by means of promoting photo‐oxidation of biological molecules (photodynamic action, PDA).
Daza de Moraes Vaz Batista, Filgueira, Diana Paula, Salomão de Freitas, Ana Paula, de Souza Votto, Gilberto, Fillmann, José Maria, Monserrat, Laura Alicia, Geracitano, Gilma, Santos Trindade   +6 more
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The exosome pathway in K562 cells is regulated by Rab11

Journal of Cell Science, 2002
During maturation, reticulocytes lose some membrane proteins that are not required on the mature red cell surface. The proteins are released into the extracellular medium associated with vesicles that are formed by budding of the endosomal membrane into the lumen of the compartment; this process results in the formation of multivesicular bodies (MVBs).
Ariel, Savina, Michel, Vidal, Maria I, Colombo   +2 more
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A kinetic and clonal analysis of heterogeneity in K562 cells

Journal of Cellular Physiology, 1984
AbstractExpression of markers of differentiation was measured in a clone of the continuous cell line K562, derived originally from the cells of a patient with leukemia. Three of the markers were lineage specific, R18 for erythropoiesis and 80H.5 and My‐1 for granulopoiesis. The fourth marker was the self‐renewal capacity of clonogenic cells.
S, Alder, A, Ciampi, E A, McCulloch
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BCL11A represses HBG transcription in K562 cells

Blood Cells, Molecules, and Diseases, 2009
BCL11A on chromosome 2p16 was recently shown to be a major quantitative trait locus for Hb F level and F-cell number in several populations with or without beta-hemoglobinopathy. We now show that BCL11A isoforms are expressed in K562 cells. Butyrate induction of HBG globin production in K562 is associated with reduced BCL11A.
Zhiyi, Chen, Hong-yuan, Luo, Martin H, Steinberg, David H K, Chui   +3 more
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