Results 141 to 150 of about 75,344 (250)

Inhibitory Effect Of Mesenchymal Stem cells Co Culture On Erythroid Differentiation Of K562 Cells Compared To Control Group

Cell Journal, 2017
Objective Bone marrow mesenchymal stem cells (BMMSCs) reside in the bone marrow and control the process of hematopoiesis. They are an excellent instrument for regenerative treatment and co-culture with hematopoietic stem cells (HSCs).
Karim Shams, Mahshid Saleh, Aliakbar movassaghpour, parvin akbarzadeh, Zahra molaeipour   +4 more
doaj  

Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells. [PDF]

J Enzyme Inhib Med Chem, 2023
Zhang G, Tang Z, Fan S, Li C, Li Y, Liu W, Long X, Zhang W, Zhang Y, Li Z, Wang Z, Chen D, Ouyang G.   +12 more
europepmc   +1 more source

An Immunomodulating Peptide With Potential to Counteract Endometriosis

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 2, April 2026.
ABSTRACT Endometriosis is underpinned by dysfunctional immune responses resulting in failure to clear ectopic endometrial lesions from the peritoneal cavity. The pelvic milieu comprising immature dendritic cells, dysfunctional cytotoxic lymphocytes, and an imbalance in production of interleukin‐12 isoforms including Type I/II interferons (IFNs) is ...
Michael Agrez
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

Cancer Science, Volume 117, Issue 4, Page 896-903, April 2026.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

Novel peptide myristoly-CM4 induces selective cytotoxicity in leukemia K562/MDR and Jurkat cells by necrosis and/or apoptosis pathway

Drug Design, Development and Therapy, 2019
Huidan Zhang,* Dongju Han,* Tongtong Lv, Kehang Liu, Yunqing Yang, Xixi Xu, Yuqing ChenDepartment of Biochemistry, Life Sciences College, Nanjing Normal University, Nanjing, People’s Republic of China*These authors contributed equally to this ...
Zhang H, Han D, Lv T, Liu K, Yang Y, Xu X, Chen Y   +6 more
doaj  

Function and mechanism of cancer-testis antigen CT63 in chronic myeloid leukemia

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To explore the effects of the cancer-testis antigen (CTA) family member CT63 on proliferation, differentiation, and tumorigenicity of chronic myeloid leukemia (CML) cells, and uncover the underlying molecular mechanisms.Methods·The link between
KONG Ruxin, ZHOU Yaqun, WEI Tingyi, LEI Ming   +3 more
doaj   +1 more source

Erythroid Differentiation Dependent Interaction of VPS13A with XK at the Plasma Membrane of K562 Cells. [PDF]

Contact (Thousand Oaks), 2023
Amos C, Xu P, De Camilli P.
europepmc   +1 more source

Ethical and Regulatory Considerations in the Clinical Translation of Pluripotent Stem Cell‐Derived NK Cell Therapies

Cell Proliferation, Volume 59, Issue 4, April 2026.
Advancements in the generation of human pluripotent stem cell‐derived natural killer (PSC‐NK) cells have attracted considerable attention within the biomedical research community, offering a promising off‐the‐shelf technique for universal immune therapy.
Qianwen Chen, Jianwei Lv, Xinwei Xie, Hanlin Zhu, Zhenyu Xiao, Yaojin Peng   +5 more
wiley   +1 more source

Role of Calcium-Activated Potassium Channels in Proliferation, Migration and Invasion of Human Chronic Myeloid Leukemia K562 Cells. [PDF]

Membranes (Basel), 2023
Vasileva VY, Khairullina ZM, Sudarikova AV, Chubinskiy-Nadezhdin VI.   +3 more
europepmc   +1 more source

GM-K562 Cell Vaccine [PDF]

, 2020
openaire   +1 more source