Results 131 to 140 of about 4,454,791 (262)

iPSC‐Derived iNK Progenitors Engraft and Generate NK Cells in Unconditioned and Autologous Immune Humanized Mice

Cell Proliferation, EarlyView.
Infusion of CXCR4‐expressing iNK progenitor (iNKP) cells derived from iPSCs can continuously generate iNK cells in an unconditioned and autologous PBMC humanised hIL15 mouse model. iNKP cell therapy has the potential to treat patients without the requirement for prior lymphodepletion. ABSTRACT NK cells exhibit inherently short persistence in vivo. Allo‐
Min Zhang, Zhiqian Wang, Yanhong Liu, Leqiang Zhang, Fangxiao Hu, Chengxiang Xia, Mengyun Zhang, Tongjie Wang, Qitong Weng, Hanmeng Qi, Yanping Zhu, Lijuan Liu, Dehao Huang, Hong‐Hu Zhu, Jinyong Wang   +14 more
wiley   +1 more source

Cytokines secreted from bone marrow derived mesenchymal stem cells promote apoptosis and change cell cycle distribution of K562 cell line as clinical agent in cell transplantation.

PLoS ONE, 2019
Mesenchymal stem cells (MSCs) are of special interest due their potential clinical use in cell-based therapy. Therapies engaging MSCs are showing increasing promise in the cancer treatment and anticancer drug screening applications. A multitude of growth
Ezzatollah Fathi, Raheleh Farahzadi, Behnaz Valipour, Zohreh Sanaat   +3 more
doaj   +1 more source

Regulation of erythroid differentiation in K562 cells by the EPAS1-IRS2 axis under hypoxic conditions. [PDF]

Front Cell Dev Biol, 2023
Gao Z, Li Z, Li X, Xiao J, Li C.
europepmc   +1 more source

Inhibitory Effect of Hydroxyapatite Nanoparticles on K562 Cells

, 2011
HAP Nanoparticles Was Synthesized by Homogeneous Precipitation. the Size Distribution, Crystallization Degree and Morphology of the Precipitation Were Characterized by Laser Granularity Instrument, X-Ray Diffraction (XRD), and Transmission Electron ...
Xin Yu Wang, Pei Chen, Shi Pu Li, Hong Lian Dai, Yin Chao Han   +4 more
core   +1 more source

Post‐Hoc Long‐Read Sequencing Links Leukemic Mutation Status to Single‐Cell Transcriptomes

European Journal of Haematology, EarlyView.
ABSTRACT Single‐cell RNA‐sequencing‐based characterization of cells that belong to the neoplastic clone is a major challenge in hematologic neoplasms, where malignant and normal cells coexist. Confident molecular profiling requires simultaneous analysis of gene expression and genetic mutations in individual cells, an ability that is not supported by ...
Sofia Papavasileiou, Chenyan Wu, Daryl Boey, Lucille Margerie, Jiezhen Mo, Ulla Olsson‐Strömberg, Stina Söderlund, Gunnar Nilsson, Joakim S. Dahlin   +8 more
wiley   +1 more source

Smenospongine, a Sesquiterpene Aminoquinone from a Marine Sponge, Induces G1 Arrest or Apoptosis in Different Leukemia Cells

Marine Drugs, 2008
Smenospongine, a sesquiterpene aminoquinone isolated from the marine sponge Dactylospongia elegans, was previously reported by us to induce erythroid differentiation and G1 phase arrest of K562 chronic myelogenous leukemia cells.
Motomasa Kobayashi, Toshiyuki Sakai, Yoshihiro Sowa, Shunji Aoki, Dexin Kong   +4 more
doaj  

Characterization of K562 cells: uncovering novel chromosomes, assessing transferrin receptor expression, and probing pharmacological therapies. [PDF]

Cell Mol Life Sci, 2023
Karagiannis TC, Wall M, Ververis K, Pitsillou E, Tortorella SM, Wood PA, Rafehi H, Khurana I, Maxwell SS, Hung A, Vongsvivut J, El-Osta A.   +11 more
europepmc   +1 more source

Changes in miRNA activity induced by TPA in K562 cells.

, 2012
(A) Morphological changes in K562 cells induced by TPA. K562 cells were cultured in DMEM (10% FBS) containing 16 nM TPA. Twenty-four hours later, the morphology of K562 cells was altered.
Xiaoyan Dong (190278), Zhijian Wu (167292), Jianxin Lu (28270), Jinzhong Chen (190294), Xiaobing Wu (190298), Yue Wang (65477), Xuerong Liu (190284), Zheyue Dong (190289), Gang Zheng (29050), Wei Shen (149127), Wenhong Tian (190273), Gang Wang (36685)   +11 more
core   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Cerium oxide nanoparticles-assisted aptasensor for chronic myeloid leukaemia detection

ADMET and DMPK
Background and purpose: Chronic myeloid leukaemia (CML) is one of the most lethal types of leukaemia and can rapidly progress if not treated properly. Therefore, having an effective diagnostic strategy is crucial.
Yuspian Nur, Yeni Wahyuni Hartati, Muhammad Ihda HL Zein, Irkham Irkham, Shabarni Gaffar, Toto Subroto   +5 more
doaj   +1 more source