Results 111 to 120 of about 10,434 (197)
Changes in miRNA activity induced by TPA in K562 cells.
(A) Morphological changes in K562 cells induced by TPA. K562 cells were cultured in DMEM (10% FBS) containing 16 nM TPA. Twenty-four hours later, the morphology of K562 cells was altered.
Xiaoyan Dong (190278) +11 more
core +1 more source
Background Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors.
Alexandra Tremblay-McLean +4 more
doaj +1 more source
LPS‐stimulated macrophages exhibit high glycolytic flux, with pyruvate preferentially converted to lactate even under normoglycemic conditions, limiting pyruvate availability for the tricarboxylic acid (TCA) cycle and reducing oxygen consumption rate (OCR).
Jila Nasirzade +8 more
wiley +1 more source
Reversion of multidrug resistance in leukemia K562 cells by RNA interference targeting Apollon gene
Background and purpose: Apollon gene is highly expressed in leukemia and other tumors. The study aimed to discuss whether RNAi technology can reverse multidrug resistance of chronic myeloid leukemia cell line K562 through constructing a eukaryotic vector
贾秀红, 孝飞飞, 李建厂
doaj
Affinity tuning of anti‐HLA‐A2 CARs reveals that lower‐affinity CAR‐Tregs exhibit reduced avidity and enhanced serial engagement, leading to increased activation and trogocytosis. These properties promote improved tissue infiltration, persistence, and survival in vivo, demonstrating that optimizing receptor–antigen dynamics enhances the therapeutic ...
Ada Sera Kurt +12 more
wiley +1 more source
Icaritin induces K562 cells or primary cells apoptosis.
A. Morphological features for apoptosis in untreated and Icaritin-treated K562 cells were revealed by Hoechst 33258 staining. Condensed chromatin and apoptotic body could be found in Icaritin-treated K562 cells by fluorescence microscope (Olympus, B×50);
Xin fu Zhou (345786) +13 more
core +1 more source
Expression of GFP-nectin-1 in human K562 cells.
(A) K562 cells transiently transfected with plasmid pCK495 express nectin-1 with GFP tagged at the N-terminus. GFP-nectin-1 is expressed at the cell surface and accumulates at cell-cell contacts. Images of GFP fluorescence, magnification 40x.
Jessenia Roldan (6331394) +6 more
core +1 more source
Protein expressions of CD44, Caveolin-1, and B-catenin in K562 and K562-IR cells.
A. CD44 immunofluorescence staining. DAPI was used for nuclear visualization. Total corrected cellular fluorescence (TCCF) intensity of CD44 immunofluorescence images (right).
Eda Acikgoz (816259) +7 more
core +1 more source
Smenospongine, a sesquiterpene aminoquinone isolated from the marine sponge Dactylospongia elegans, was previously reported by us to induce erythroid differentiation and G1 phase arrest of K562 chronic myelogenous leukemia cells.
Motomasa Kobayashi +4 more
doaj
Vacuolization as a Novel Approach to Cancer Therapy
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source

