Results 91 to 100 of about 4,454,791 (262)

Apoptosis study in K562 cells.

open access: yes, 2013
(A) Morphological analysis of K562 cells after treatment with native pac, pac-MNPs and lec-pac-MNPs (Conc. 10 ng/ml) after 24 and 48 h by confocal microscopy. (B) Induction of apoptosis in K562 cell line by native pac, pac-MNPs and lec-pac-MNPs (Conc. 10
Abhalaxmi Singh (339133)   +2 more
core   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch   +7 more
wiley   +1 more source

Effect of interaction of magnetic nanoparticles of Fe3O4 and artesunate on apoptosis of K562 cells

open access: yesInternational Journal of Nanomedicine, 2011
Ying Wang1, Yuxiang Han1, Yingying Yang1, Jingci Yang1, Xiaonan Guo1, Jingnan Zhang1, Ling Pan1, Guohua Xia2, Baoan Chen21Department of Hematology, the 2nd Hospital of Hebei Medical University, People’s Republic of China; 2Department of ...
Wang Y   +8 more
doaj  

Dengue virus infection mediates HMGB1 release from monocytes involving PCAF acetylase complex and induces vascular leakage in endothelial cells.

open access: yesPLoS ONE, 2012
High mobility group box 1 (HMGB1) protein is released from cells as a pro-inflammatory cytokine in response to an injury or infection. During dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS), a number of pro-inflammatory cytokines are released,
Siew Pei Ong   +4 more
doaj   +1 more source

Eventos apoptóticos induzidos pelo Lauril Galato sobre células de leucemia mielóide aguda humana K562 [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em Ciências MédicasThe purpose of the present study was to investigate the sensibility of human myeloid leukemia cells (K562) to the ...
Ferreira, Samira Cardoso
core  

PH II-7 induces apoptosis in K562 and K562/A02 cells.

open access: yes, 2012
(A) Induction of apoptosis by PH II-7 and ADM (both treated for 24 hours, concentrations indicated in the figure) in K562 or K562/A02 cells. (B) The induction of apoptosis in K562 and K562/A02 cells by different concentrations of PH II-7(300 nM, 600 nM ...
Yunhui Hu (179592)   +14 more
core   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

open access: yesBiotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga   +2 more
wiley   +1 more source

Bone marrow‐like viscosity affects imatinib resistance in chronic myeloid leukemia

open access: yesBiotechnology Progress, EarlyView.
Physical cues such as microenvironmental viscosity have been recognized as important regulators in controlling cell functions. However, even though the bone marrow (BM) is a viscous tissue in which cells respond mechanically to both the matrix stiffness and the viscosity of surrounding fluid, the impact of microenvironmental viscosity on imatinib (IM ...
Tianjiao Zeng   +6 more
wiley   +1 more source

Hemin‐dependent induction and internalization of CD38 in K562 cells

open access: yesJournal of Cellular Biochemistry, 2003
AbstractThe cell surface antigen, CD38, is a bifunctional ecto‐enzyme, which is predominantly expressed on hematopoietic cells during differentiation. In the present study, it is shown that hemin treatment of K562 cells gives rise to induction of enzymatic activities inherent to CD38.
Yalcintepe, L   +5 more
openaire   +3 more sources

Synthesis of Tris(indol‐3‐yl)methanes From Indoles, CO2, and Dimethylphenylsilane With BPh3: Two‐Step Construction of π‐Conjugated Systems

open access: yesChemistry – A European Journal, EarlyView.
Tris(indol‐3‐yl)methanes were synthesized from indoles, CO2, and PhMe2SiH in the presence of BPh3 in acetonitrile at 50°C. One product, tris(4‐bromo‐1‐methylindol‐3‐yl)methane, underwent a palladium‐catalyzed cascade reaction for the formation of a novel polycyclic heteroaromatic compound, where the methine C(sp3) atom originating from CO2 was ...
Sha Li   +5 more
wiley   +1 more source

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