Results 201 to 210 of about 75,344 (250)

Glycophorins of human erythroleukemic K562 cells

Archives of Biochemistry and Biophysics, 1987
Glycophorins related to alpha glycophorin, of the human erythrocyte membrane, were isolated from human erythroleukemic K562 cells. The glycophorins were purified using sodium dodecyl sulfate (SDS)/trichloroacetic acid fractionation and Folch and hot phenol extractions. 0.1-0.2 micrograms was obtained/10(8) cells, or approximately a 15% yield.
R E, Silver, A M, Adamany, O O, Blumenfeld   +2 more
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K562—A human erythroleukemic cell line

International Journal of Cancer, 1979
AbstractWe have studied the surface membrane properties of the human leukemic cell line K562 which previously has been reported to represent an early stage of granulocyte maturation. The surface glycoprotein pattern of the K562 cells obtained after galactose oxidase‐NaB[3H]4 labelling and slab gel electrophoresis shows striking similarities with that ...
L C, Andersson, K, Nilsson, C G, Gahmberg   +2 more
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Stereoselective Accumulation of Propranolol Enantiomers in K562 and K562/ADR Cells

Chirality, 2013
ABSTRACTThe stereoselective uptake of propranolol enantiomers was investigated by using the K562 and K562 adriamycin‐resistant cell line (K562/ADR) as a model. An enantioselective RP‐HPLC method was applied to determine the accumulation of propranolol (PPL) stereoisomers in K562 and K562/ADR cells.
Xiao-Li, Zheng, Qin-Qin, Yu, Yi, Wang, Su, Zeng   +3 more
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Megakaryoblastic differentiation of proerythroblastic K562 cell-line cells

Leukemia Research, 1984
The human proerythroblastic leukemia cell-line K562 was induced to differentiate into megakaryocytic cells by 12-O-tetradecanoylphorbol-13-acetate (TPA). Megakaryocytic differentiation was detected when lineage-specific monoclonal antibodies were used to monitor the effect of TPA on K562 cells. A monoclonal anti-platelet antibody (C17) directed against
P A, Tetteroo, F, Massaro, A, Mulder, R, Schreuder-van Gelder, A E, von dem Borne   +4 more
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Mechanism of Simvastatin-Induced K562 Cell Apoptosis

Pharmacology, 2009
Statins are being widely used for the therapy and prevention of several types of tumors, including human chronic myelogenous leukemia, but the underlying molecular mechanisms still remain unknown. Therefore, inhibition of cell proliferation, apoptosis and involved molecules were investigated in K562 cells after incubation with simvastatin.The results ...
Yong-Chang, Yang, Dai-Wen, Xiao, Hua, Liu, Liang-Min, Chuan, Ya-Li, Zeng, Ding-An, Zhou, Wen, Liu, Guo-Qiang, Xu, Wen-Fang, Huang   +8 more
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Variation amongst K562 cell cultures.

Experimental hematology, 1983
K562 cell cultures were obtained from three laboratories (A, B and C) outside our institution, and were designated according to source as K562A, K562B or K562C. The cultures obtained were constitutive or "wild type" K562 cell cultures, not cloned sublines.
I W, Dimery, D D, Ross, J R, Testa, S K, Gupta, R L, Felsted, A, Pollak, N R, Bachur   +6 more
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BCL11A represses HBG transcription in K562 cells

Blood Cells, Molecules, and Diseases, 2009
BCL11A on chromosome 2p16 was recently shown to be a major quantitative trait locus for Hb F level and F-cell number in several populations with or without beta-hemoglobinopathy. We now show that BCL11A isoforms are expressed in K562 cells. Butyrate induction of HBG globin production in K562 is associated with reduced BCL11A.
Zhiyi, Chen, Hong-yuan, Luo, Martin H, Steinberg, David H K, Chui   +3 more
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Geldanamycin Induces Cell Cycle Arrest in K562 Erythroleukemic Cells

IUBMB Life, 1999
AbstractGeldanamycin (GA), a benzoquinone ansamycin, is one of the specific inhibitors of 90‐kDa heat shock protein and induces growth inhibition and apoptosis in certain cancer cell lines. We have investigated the mechanism of GA‐induced growth inhibition in K562 erythroleukemic cells.
H R, Kim, C H, Lee, Y H, Choi, H S, Kang, H D, Kim   +4 more
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Stromal cell-dependent terminal maturation of K562 erythroleukaemia cells

Leukemia Research, 1991
K562 cells were cultured over monolayers of various cell types for four days and the characteristics of those cells which became firmly adherent to such monolayers studied. The monolayers used were composed of stromal cells derived from human bone marrow, two human fibroblast lines, human umbilical cord-derived endothelial cells, bone marrow ...
S R, Zuhrie, S N, Wickramasinghe
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Apoptosis inducing effect of meisoindigo on K562 cells

Chinese Journal of Integrated Traditional and Western Medicine, 1999
To study the effect of meisoindigo on human chronic myelogenous leukemia (CML) cell line K562 cells for exploring the mechanism of meisoindigo in treatment of CML.Multiple methods, including dose-response curve, trypan blue exclusion, cytomorphology, DNA electrophoresis, flow cytometry and TUNEL (TdT mediated dUTP nick and labeling), were used to ...
L, Song, L, Qian
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