A Transmembrane Accessory Subunit that Modulates Kainate-Type Glutamate Receptors
, 2009 SummaryGlutamate receptors play major roles in excitatory transmission in the vertebrate brain. Among ionotropic glutamate receptors (AMPA, kainate, NMDA), AMPA receptors mediate fast synaptic transmission and require TARP auxiliary subunits.
Burlingame, Alma L. +21 more
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Structure and Mechanism of Kainate Receptor Modulation by Anions
, 2007 SummaryL-glutamate, the major excitatory neurotransmitter in the human brain, activates a family of ligand-gated ion channels, the major subtypes of which are named AMPA, kainate, and NMDA receptors.
Plested, Andrew J.R., Mayer, Mark L.
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Kainate receptor subunit 1 (GRIK1) risk variants and GRIK1 deficiency were detected in the Indian ADHD probands. [PDF]
Sci Rep, 2022 Chatterjee M +4 more
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The emerging role of kainate receptor functional dysregulation in pain. [PDF]
Mol Pain, 2021 Li H, Li J, Guan Y, Wang Y.
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Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. [PDF]
Elife, 2021 Khanra N +4 more
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Surface biotinylation of primary neurons to monitor changes in AMPA receptor surface expression in response to kainate receptor stimulation. [PDF]
STAR Protoc, 2021 Nair JD, Henley JM, Wilkinson KA.
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Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD. [PDF]
iScience, 2021 Nair JD +8 more
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Structures of partially occupied hetero-tetramers provide insight into kainate receptor activation and desensitization. [PDF]
Nat CommunKhanra NK +6 more
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, 2002 The dissociative anaesthetic, ketamine, is commonly known as a NMDA receptor channel blocker. However, additional mechanisms of action probably contribute to its various clinical effects.
Leong, Darrell Andrew
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