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Cerebellar Kainate Receptor-Mediated Facilitation of Glutamate Release Requires Ca2+-Calmodulin and PKA. [PDF]
Front Mol Neurosci, 2018 Falcón-Moya R +3 more
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Mapping the multi-domain allosteric network for CKAMP44 modulation of AMPA receptors. [PDF]
J Biol ChemBharti P, Visal S, Vinnakota R, Kumar J.
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Cell and Tissue Research, 2006
Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors.
Paulo, Pinheiro, Christophe, Mulle
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Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors.
Paulo, Pinheiro, Christophe, Mulle
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Current Opinion in Neurobiology, 2000
Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.
M, Frerking, R A, Nicoll
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Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.
M, Frerking, R A, Nicoll
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Kainate receptors in the hippocampus
European Journal of Neuroscience, 2014AbstractKainate receptors (KARs) consist of a family of ionotropic glutamate receptors composed of the combinations of five subunits, GluK1–GluK5. Although KARs display close structural homology with AMPA receptors, they serve quite distinct functions.
Mario, Carta +3 more
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2010
Glutamate is the major fast excitatory amino acid transmitter in the CNS, and exerts its action through receptors that function as ion channels such as NMDA receptors (NMDARs), AMPA receptors (AMPARs), and kainate receptors (KARs), and also through signaling cascades via metabotropic receptors.
Erik B, Bloss, Richard G, Hunter
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Glutamate is the major fast excitatory amino acid transmitter in the CNS, and exerts its action through receptors that function as ion channels such as NMDA receptors (NMDARs), AMPA receptors (AMPARs), and kainate receptors (KARs), and also through signaling cascades via metabotropic receptors.
Erik B, Bloss, Richard G, Hunter
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Current Opinion in Pharmacology, 2006
Glutamate receptors constitute a complex signalling system at most of the excitatory synapses in the brain. Of the known ionotropic glutamate receptors, kainate receptors are ubiquitous in the central nervous system, and a considerable amount of data indicates that this class of receptors is present at both sides of the synapse.
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Glutamate receptors constitute a complex signalling system at most of the excitatory synapses in the brain. Of the known ionotropic glutamate receptors, kainate receptors are ubiquitous in the central nervous system, and a considerable amount of data indicates that this class of receptors is present at both sides of the synapse.
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Physiopathology of kainate receptors in epilepsy
Current Opinion in Pharmacology, 2015Kainate receptors (KARs) are tetrameric ionotropic glutamate receptors composed of the combinations of five subunits GluK1-GluK5. KARs are structurally related to AMPA receptors but they serve quite distinct functions by regulating the activity of synaptic circuits at presynaptic and postsynaptic sites, through either ionotropic or metabotropic actions.
Valérie, Crépel, Christophe, Mulle
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