Results 111 to 120 of about 18,286 (218)

Glutamate Receptors in Nucleus Accumbens Can Modulate Canabinoid-Induced Antinociception in Rat’s Basolateral Amygdala

Basic and Clinical Neuroscience, 2012
Introduction: It has been shown that administration of WIN55,212-2, a cannabinoid receptor agonist, into the basolateral amygdala (BLA), dose-dependently increases the thermal latency to withdrawal in the tail-.ick test and decreases pain related ...
Mohadeseh Ghalandari-Shamami, Majid Hassanpour-Ezatti, Abbas Haghparast   +2 more
doaj  

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

, 1991
Fast excitatory transmission in the vertebrate central nervous system is mediated mainly by L-glutamate. On the basis of pharmacological, physiological and agonist binding properties, the ionotropic glutamate receptors are classified into NMDA (N-methyl ...
Bernhard Bettler, Hermans-Borgmeyer, I., Heinemann, S., Stephen Heinemann, Bettler, B., Jan Egebjerg, Egebjerg, J., Irm Hermans-Borgmeyer   +7 more
core   +1 more source

Kainate-induced apoptosis in cultured murine cerebellar granule cells elevates expression of the cell cycle gene cyclin D1

, 1998
Recent evidence suggests that neuronal apoptosis is the consequence of an inappropriate reentry into the cell cycle. Expression of the cell cycle gene cyclin D1, a G1-phase cell cycle regulator, was examined in primary cultures of murine cerebellar ...
NS Cheung (14539535), SF Giardina (15885641), MT Reid (15885647), PM Beart (14539538)   +3 more
core  

Kainate Receptor Antagonists: Recent Advances and Therapeutic Perspective. [PDF]

Int J Mol Sci, 2023
Chałupnik P, Szymańska E.
europepmc   +1 more source

Kainate-induced apoptosis correlates with c-Jun activation in cultured cerebellar granule cells.

, 1998
We have investigated the involvement of c-Jun in cell death induced by exposure of primary cultures of murine cerebellar granule cells to the glutamate receptor agonist kainate (KA) and evaluated its possible use as a marker for apoptosis.
FY Carroll (15885638), NS Cheung (14539535), SF Giardina (15885641), JA Larm (15885635), PM Beart (14539538)   +4 more
core  

AMPA, kainate, and quisqualate activate a common receptor-channel complex on embryonic chick motoneurons

, 1988
The actions of the putative quisqualate-selective agonist DL-alpha- amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) were examined in identified embryonic chick motoneurons using gigaseal recording techniques and compared with properties of the
J Yang, CF Zorumski
core   +1 more source

Clustered mutations in the GRIK2 kainate receptor subunit gene underlie diverse neurodevelopmental disorders. [PDF]

Am J Hum Genet, 2021
Stolz JR, Foote KM, Veenstra-Knol HE, Pfundt R, Ten Broeke SW, de Leeuw N, Roht L, Pajusalu S, Part R, Rebane I, Õunap K, Stark Z, Kirk EP, Lawson JA, Lunke S, Christodoulou J, Louie RJ, Rogers RC, Davis JM, Innes AM, Wei XC, Keren B, Mignot C, Lebel RR, Sperber SM, Sakonju A, Dosa N, Barge-Schaapveld DQCM, Peeters-Scholte CMPCD, Ruivenkamp CAL, van Bon BW, Kennedy J, Low KJ, Ellard S, Pang L, Junewick JJ, Mark PR, Carvill GL, Swanson GT.   +38 more
europepmc   +2 more sources

Decreased numerical density of kainate receptor-positive neurons in the orbitofrontal cortex of chronic schizophrenics [PDF]

, 2018
We utilised postmortem brain tissue to quantify sections of left and right orbitofrontal cortex (area 11) from nine schizophrenic and eight control patients from the Charing Cross Prospective Schizophrenia Study immunostained for the presence of the ...
Garey, L., Von Bussmann, K. A., Hirsch, S.   +2 more
core  

Synthesis of a Series of Aryl Kainic Acid Analogs and Evaluation in Cells Stably Expressing the Kainate Receptor humGluR6

, 2016
The synthesis and pharmacological characterization of a novel series of 4-aryl-substituted kainic acid analogs are described. Receptor affinities were determined on recombinantly expressed humGluR6 kainate receptors and on [3H]kainate binding to rat ...
Buddy E. Cantrell (2725051), David Bleakman (2497171), Dennis M. Zimmerman (2725048), Louise N. Farrell (3018546), James A. Monn (1947361), Joseph P. Tizzano (2674249), Ken H. Hoo (3018543), Ian A. Pullar (3018549), Rajender K. Kamboj (3013455)   +8 more
core   +1 more source

GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors. [PDF]

iScience, 2023
Nair JD, Wilkinson KA, Yucel BP, Mulle C, Vissel B, Mellor J, Henley JM.   +6 more
europepmc   +1 more source