Results 101 to 110 of about 18,286 (218)
Functional implications of the exon 9 splice insert in GluK1 kainate receptors
Kainate receptors are key modulators of synaptic transmission and plasticity in the central nervous system. Different kainate receptor isoforms with distinct spatiotemporal expressions have been identified in the brain.
Surbhi Dhingra +3 more
doaj +1 more source
Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors
Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists.
David P.D. Woldbye +7 more
doaj +1 more source
Presynaptic Kainate Receptors Regulate Spinal Sensory Transmission
Small diameter dorsal root ganglion (DRG) neurons, which include cells that transmit nociceptive information into the spinal cord, are known to express functional kainate receptors.
Timothy J. Wilding +4 more
core +1 more source
Kainate receptors in epilepsy [PDF]
AbstractKainate receptors (KARs) belong to the glutamatergic receptor family and they are assembled from various combinations of GluK1–GluK5 subunits. In the central nervous system (CNS), these receptors are involved in fundamental neuronal operation‐like synaptic transmission.
openaire +1 more source
Molecular pharmacology of AMPA receptor trafficking proteins - TARPs - evidence for an association with 5HT(_2c) receptors [PDF]
There has been an increasing awareness of the involvement of neurotransmitters other than serotonin in depression, with new antidepressants possessing effects on other receptor types, such as Agomelatine®, an antagonist of 5HT(_2c) receptors that ...
Donoghue, Peter, Donoghue , Peter
core
During the first week of life, there is a shift from kainate to AMPA receptor-mediated thalamocortical transmission in layer IV barrel cortex. However, the mechanisms underlying this change and the differential properties of AMPA and kainate receptor ...
core +1 more source
A novel kainate receptor in the insect nervous system
The pharmacology of excitatory amino acid receptors on an identified neurone in the insect central nervous system was investigated using single electrode recording techniques.
Bai, D., Sattelle, D. B., Wafford, K. A.
core +1 more source
BACKGROUND: Alterations in AMPA and kainate receptor binding have been revealed in post-mortem schizophrenic brains. As most patients had been treated with antipsychotics, medication effects cannot be excluded as a possible explanation for these results.
Muller, B. +6 more
core +1 more source
Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G. +10 more
core

