Results 81 to 90 of about 17,392 (217)

Ionotropic receptors at hippocampal mossy fibres: roles in axonal excitability, synaptic transmission and plasticity

Frontiers in Neural Circuits, 2013
Dentate granule cells process information from the enthorinal cortex en route to the hippocampus proper. These neurons have a very negative resting membrane potential and are relatively silent in the slice preparation.
Arnaud J Ruiz, Dimitri M Kullmann
doaj   +1 more source

Characterization of the kainate-binding domain of the glutamate receptor GluR-6 subunit [PDF]

, 1998
Kari Keinänen, Annukka Jouppila, Arja Kuusinen   +2 more
openalex   +1 more source

Structure and gating of kainate receptors

Frontiers in Pharmacology
Ionotropic glutamate receptors (iGluRs) are crucial for fast excitatory neurotransmission in the mammalian central nervous system (CNS). Kainate receptors (KARs), a subclass of iGluRs, are tetrameric, ligand-gated ion channels that play key modulatory roles at both pre- and post-synaptic sites within neuronal circuits and in the regulation of synaptic ...
Gangwar, Shanti P., Yelshanskaya, Maria V., Yen, Laura Y., Newton, Thomas P., Sobolevsky, Alexander I.   +4 more
openaire   +3 more sources

Antagonism of ionotropic glutamate receptors attenuates chemical ischemia-induced injury in rat primary cultured myenteric ganglia.

PLoS ONE, 2014
Alterations of the enteric glutamatergic transmission may underlay changes in the function of myenteric neurons following intestinal ischemia and reperfusion (I/R) contributing to impairment of gastrointestinal motility occurring in these pathological ...
Elisa Carpanese, Paola Moretto, Viviana Filpa, Silvia Marchet, Elisabetta Moro, Francesca Crema, Gianmario Frigo, Cristina Giaroni   +7 more
doaj   +1 more source

Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

Neurobiology of Disease, 1994
Kainate-activated Co2+uptake, a histochemical method that identifies cells bearing Ca2+-permeable AMPA/kainate receptors, labels approximately 15% of murine cortical neurones in cell culture.
Dorothy M. Turetsky, Lorella M.T. Canzoniero, Stefano L. Sensi, John H. Weiss, Mark P. Goldberg, Dennis W. Choi   +5 more
doaj   +1 more source

Kainate receptors in epilepsy [PDF]

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2013
AbstractKainate receptors (KARs) belong to the glutamatergic receptor family and they are assembled from various combinations of GluK1–GluK5 subunits. In the central nervous system (CNS), these receptors are involved in fundamental neuronal operation‐like synaptic transmission.
openaire   +1 more source

Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

Neurobiology of Disease, 2005
Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists.
David P.D. Woldbye, Avtandil Nanobashvili, Andreas T. Sørensen, Henriette Husum, Tom G. Bolwig, Gunnar Sørensen, Patrik Ernfors, Merab Kokaia   +7 more
doaj   +1 more source

Kainate Receptors

, 1999
Peer ...
openaire   +2 more sources

The Lurcher Mutation Identifies δ2 as an AMPA/Kainate Receptor-Like Channel That Is Potentiated by Ca²⁺ [PDF]

, 2000
Lonnie P. Wollmuth, Thomas Kuner, Claudia Jatzke, Peter H. Seeburg, Nathaniel Heintz, Jian Zuo   +5 more
openalex   +1 more source

Prostaglandin E₂-Induced Masculinization of Brain and Behavior Requires Protein Kinase A, AMPA/Kainate, and Metabotropic Glutamate Receptor Signaling [PDF]

, 2009
Christopher L. Wright, Margaret M. McCarthy   +1 more
openalex   +1 more source