Results 81 to 90 of about 15,689 (185)

Ionotropic receptors at hippocampal mossy fibres: roles in axonal excitability, synaptic transmission and plasticity

Frontiers in Neural Circuits, 2013
Dentate granule cells process information from the enthorinal cortex en route to the hippocampus proper. These neurons have a very negative resting membrane potential and are relatively silent in the slice preparation.
Arnaud J Ruiz, Dimitri M Kullmann
doaj   +1 more source

Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Astrocytes contribute to the pathophysiology of acquired epilepsy. However, less is known about their contribution to genetic epilepsy syndromes which often exhibit frequent comorbidity with neurodevelopmental and psychiatric disorders. Epileptic seizures are also frequently present in neurodevelopmental disorders.
Jenny Lange, Erica Zhao, Ellie O'Connell, Olivia Gillham, Amy McTague   +4 more
wiley   +1 more source

Coordinated interplay between palmitoylation, phosphorylation and SUMOylation regulates kainate receptor surface expression [PDF]

Front Mol Neurosci, 2023
Yucel BP, Al Momany EM, Evans AJ, Seager R, Wilkinson KA, Henley JM.   +5 more
europepmc   +2 more sources

Antagonism of ionotropic glutamate receptors attenuates chemical ischemia-induced injury in rat primary cultured myenteric ganglia.

PLoS ONE, 2014
Alterations of the enteric glutamatergic transmission may underlay changes in the function of myenteric neurons following intestinal ischemia and reperfusion (I/R) contributing to impairment of gastrointestinal motility occurring in these pathological ...
Elisa Carpanese, Paola Moretto, Viviana Filpa, Silvia Marchet, Elisabetta Moro, Francesca Crema, Gianmario Frigo, Cristina Giaroni   +7 more
doaj   +1 more source

Cortical neurones exhibiting kainate-activated Co2+uptake are selectively vulnerable to AMPA/kainate receptor-mediated toxicity

Neurobiology of Disease, 1994
Kainate-activated Co2+uptake, a histochemical method that identifies cells bearing Ca2+-permeable AMPA/kainate receptors, labels approximately 15% of murine cortical neurones in cell culture.
Dorothy M. Turetsky, Lorella M.T. Canzoniero, Stefano L. Sensi, John H. Weiss, Mark P. Goldberg, Dennis W. Choi   +5 more
doaj   +1 more source

Functional implications of the exon 9 splice insert in GluK1 kainate receptors

eLife
Kainate receptors are key modulators of synaptic transmission and plasticity in the central nervous system. Different kainate receptor isoforms with distinct spatiotemporal expressions have been identified in the brain.
Surbhi Dhingra, Prachi M Chopade, Rajesh Vinnakota, Janesh Kumar   +3 more
doaj   +1 more source

Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

Neurobiology of Disease, 2005
Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists.
David P.D. Woldbye, Avtandil Nanobashvili, Andreas T. Sørensen, Henriette Husum, Tom G. Bolwig, Gunnar Sørensen, Patrik Ernfors, Merab Kokaia   +7 more
doaj   +1 more source

Kainate receptors in epilepsy [PDF]

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2013
AbstractKainate receptors (KARs) belong to the glutamatergic receptor family and they are assembled from various combinations of GluK1–GluK5 subunits. In the central nervous system (CNS), these receptors are involved in fundamental neuronal operation‐like synaptic transmission.
openaire   +1 more source

Glutamate Receptors in Nucleus Accumbens Can Modulate Canabinoid-Induced Antinociception in Rat’s Basolateral Amygdala

Basic and Clinical Neuroscience, 2012
Introduction: It has been shown that administration of WIN55,212-2, a cannabinoid receptor agonist, into the basolateral amygdala (BLA), dose-dependently increases the thermal latency to withdrawal in the tail-.ick test and decreases pain related ...
Mohadeseh Ghalandari-Shamami, Majid Hassanpour-Ezatti, Abbas Haghparast   +2 more
doaj  

Kainate Receptor Antagonists: Recent Advances and Therapeutic Perspective. [PDF]

Int J Mol Sci, 2023
Chałupnik P, Szymańska E.
europepmc   +1 more source