Results 71 to 80 of about 17,392 (217)
Environmental Microbiology, Volume 28, Issue 4, April 2026.Thermal stress significantly alters signalling receptor abundance in the model cnidarian Exaiptasia diaphana. TRPA1, EP2 and GRIK2 increased under elevated temperatures, while EP4 remained unchanged, indicating differential thermal modulation of oxylipin‐ and glutamate‐linked pathways.
Andrea G. Gamba +6 more
wiley +1 more source
European Journal of Neuroscience, Volume 63, Issue 8, April 2026.Numerical cognition arises from conserved mechanisms linking genes, neural circuits and behaviour. Using zebrafish as a tractable model, behavioural assays, whole‐brain imaging and genetic analyses can be integrated to identify neural and molecular bases of quantity discrimination. This framework provides a platform for studying numerical cognition and
Mirko Zanon +3 more
wiley +1 more source
Neurobiology of Disease, 2007 α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor-mediated excitotoxicity contributes to the selective motor neuron death in amyotrophic lateral sclerosis (ALS).
Maria Andries +3 more
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 7, Page 3077-3093, 1 April 2026.Abstract figure legend A, schematic illustration of the ventral aspect of an ex vivo preparation of the entire CNS from a neonatal rat subjected to a calibrated thoracic impact. The trauma induced a large depolarising injury potential (DIP, black trace) recorded from the L5 ventral root (VRrL5), which was markedly reduced by transient receptor ...
Atiyeh Mohammadshirazi +5 more
wiley +1 more source
Біологічні студії, 2020 Background. The use of Arthropodae toxins for electrophysiological experiments is very important, but experimental data in this regard are scarce. The aim of this study was to obtain experimental data about the influence of Nephila clavata spider venom ...
O. M. Klyuchko
doaj +1 more source
Nature Communications, 2019 Exaggerated synaptic inhibition is hypothesised to be a main cause of cognitive deficits in Down syndrome models. The authors identify triplication of the kainate receptor encoding gene Grik1 as the cause of memory deficits due to a reorganization of ...
Sergio Valbuena +4 more
doaj +1 more source
Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
Journal of Medical Case Reports, 2008 Introduction A large part of research into drug addiction focuses on mesolimbic dopamine circuitry; however, both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate and dopamine D2 receptors can play a role in maintaining the ...
Arbaizar Beatriz +2 more
doaj +1 more source
GluK2-mediated excitability within the superficial layers of the entorhinal cortex.
PLoS ONE, 2009 Recent analysis of genetically modified mice deficient in different kainate receptor (KAR) subunits have strongly pointed to a role of the GluK2 subunit, mediating the vulnerability of the brain towards seizures.
Prateep S Beed +2 more
doaj +1 more source
Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures
Neurobiology of Disease, 2015 The aim of this study was to investigate the role of the synaptic metabotropic zinc receptor mZnR/GPR39 in physiological adaptation to epileptic seizures.
David Gilad +6 more
doaj +1 more source
Encephalitis with Autoantibodies against the Glutamate Kainate Receptors
, 2021 Jon Landa +21 more
openalex +1 more source