Results 81 to 90 of about 15,707 (217)

The Effect of Alpha-Lipoic Acid on Learning and Memory Deficit in a Rat Model of Temporal Lobe Epilepsy

Basic and Clinical Neuroscience, 2012
Introduction: Epilepsy is a chronic neurological disorder in which patients experience spontaneous recurrent seizures and deficiency in learning and memory.
Tourandokht Baluchnejadmojarad, Mehrdad Roghani, Mitra Kamran, Narges Karimi   +3 more
doaj   +2 more sources

Neuronal protective effect of Songling Xuemaikang capsules alone and in combination with carbamazepine on epilepsy in kainic acid-kindled rats

Pharmaceutical Biology, 2019
Context: Epilepsy is a common life-threatening neurological disorder that is often drug-resistant and associated with cognitive impairment. The traditional Chinese patent medicine Songling Xuemaikang capsules (SXC) is clinically used for epilepsy therapy
Haiyan Yang, Rui Zhang, Chen Jia, Mengyu Chen, Wen Yin, Liming Wei, Haisheng Jiao   +6 more
doaj   +1 more source

Focused ultrasound combined with drug-loaded microbubbles suppress kainic acid induced epilepsy rat model.

, 2023
Pei-hsuan Wu, Miao-Er Chien, Yi‐Jen Wu, Ching‐Hsiang Fan   +3 more
openalex   +1 more source

P38 Regulates Kainic Acid-Induced Seizure and Neuronal Firing via Kv4.2 Phosphorylation [PDF]

, 2020
Jiahua Hu, Cole Malloy, Dax A. Hoffman
openalex   +1 more source

The Effect of long-term rapamycin administration on intracellular calcium quantification and RhoA activity in kainic acid epilepsy model [PDF]

Brazilian Journal of Pharmaceutical Sciences
Epilepsy affects around 50 million people worldwide, with 30% of them being refractory epilepsy. This shows that there is still a need for novel anti-seizure medication that have different mechanisms.
Machlusil Husna, Kusworini Handono, Hidayat Sujuti, Aulanni’am Aulanni’am, Rumman Karimah, Afiyfah Kiysa Waafi, Alya Satira   +6 more
doaj   +1 more source

The effects of glycemic control on seizures and seizure-induced excitotoxic cell death

BMC Neuroscience, 2012
Background Epilepsy is the most common neurological disorder after stroke, affecting more than 50 million persons worldwide. Metabolic disturbances are often associated with epileptic seizures, but the pathogenesis of this relationship is poorly ...
Schauwecker Paula
doaj   +1 more source

In vivo measurement of hippocampal GABAA/cBZR density with [18F]-flumazenil PET for the study of disease progression in an animal model of temporal lobe epilepsy.

PLoS ONE, 2014
PurposeImbalance of inhibitory GABAergic neurotransmission has been proposed to play a role in the pathogenesis of temporal lobe epilepsy (TLE). This study aimed to investigate whether [(18)F]-flumazenil ([(18)F]-FMZ) PET could be used to non-invasively ...
Lucy Vivash, Marie-Claude Gregoire, Viviane Bouilleret, Alexis Berard, Catriona Wimberley, David Binns, Peter Roselt, Andrew Katsifis, Damian E Myers, Rodney J Hicks, Terence J O'Brien, Stefanie Dedeurwaerdere   +11 more
doaj   +1 more source

Outer hair cells stir cochlear fluids

eLife
We hypothesized that active outer hair cells drive cochlear fluid circulation. The hypothesis was tested by delivering the neurotoxin, kainic acid, to the intact round window of young gerbil cochleae while monitoring auditory responses in the cochlear ...
Choongheon Lee, Mohammad Shokrian, Kenneth S Henry, Laurel H Carney, J Christopher Holt, Jong-Hoon Nam   +5 more
doaj   +1 more source

Simultaneous BOLD fMRI and local field potential measurements during kainic acid–induced seizures [PDF]

, 2012
Antti M. Airaksinen, S. K. Hekmatyar, Neil P. Jerome, Juha‐Pekka Niskanen, J. Huttunen, Asla Pitkänen, Risto A. Kauppinen, Olli Gröhn   +7 more
openalex   +1 more source

A Formal Synthesis of (–)-Kainic Acid by Means of SmI2-Mediated Radical Cyclization

, 2018
Kazunori Takahashi, Takumi Ito, Wataru Yamada, Masayoshi Tsubuki, Toshio Honda   +4 more
openalex   +1 more source