Results 91 to 100 of about 3,839 (199)

Kallikrein immobilized on magnetic beads for activity-based assays using mass spectrometry

Frontiers in Analytical Science
A crucial step in drug discovery involves identifying active molecules, which depends on fast and efficient screening assay methods. Kallikreins a family of serine protease enzymes, play a pivotal role in biological fluids and tissues.
Camila Loreta Rocha, Carmen Lúcia Cardoso   +1 more
doaj   +1 more source

Normal thromboelastography with a markedly prolonged activated partial thromboplastin time in severe prekallikrein deficiency: Implications for perioperative hemostatic assessment

Transfusion, Volume 66, Issue 10, Page 2031-2036, October 2026.
Abstract Background Prekallikrein (PK) deficiency is a rare contact factor deficiency that can markedly prolong the activated partial thromboplastin time (aPTT) without a bleeding phenotype. Because viscoelastic hemostatic assays also rely on contact activation, their behavior in severe PK deficiency is relevant to perioperative evaluation of isolated ...
Jeremy W. Jacobs, Anton Matafonov, Patricia G. Baxter, Qiufang Cheng, Garrett S. Booth, Deva Sharma, Benjamin F. Tillman, David Gailani   +7 more
wiley   +1 more source

Nociception related biomolecules in the adult human saliva: A scoping review with additional quantitative focus on cortisol

Molecular Pain
Nociception related salivary biomolecules can be useful patients who are not able to self-report pain. We present the existing evidence on this topic using the PRISMA-ScR guidelines and a more focused analysis of cortisol change after cold pain induction
Roxaneh Zarnegar, Angeliki Vounta, Qiuyuan Li, Sara S Ghoreishizadeh   +3 more
doaj   +1 more source

kallikrein

Citation: 'kallikrein' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13356 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Fragment-Based Discovery of KLK6 and KLK7 Inhibitors. [PDF]

J Chem Inf Model
de Freitas RF, Soualmia F, Boumali R, Harrak Y, Amri CE.   +4 more
europepmc   +1 more source

Proton-activated chloride channel PACC1 as acid sensor in epidermal desquamation. [PDF]

Proc Natl Acad Sci U S A
Xia K, Liu X, Wu J, Hu J, Cheng X, Mi T, Gao B, Mo X, Lu X, Cao F, Xie C, Cao J, Pernodet N, He G, Zhou H, Yao J.   +15 more
europepmc   +1 more source

Drug Targets in Prostate Cancer: An Appetite for KLK2-Mediated Destruction. [PDF]

Clin Cancer Res
Blinka S, Yu EY.
europepmc   +1 more source

LEKTI-Grafted Sunflower Trypsin Inhibitor: A Potential Therapeutic for Skin Diseases. [PDF]

J Med Chem
Mah J, Jayarajan V, Huang X, Di WL, Macmillan D.   +4 more
europepmc   +1 more source

Real-World Clinical Evaluation of S2,3PSA Test in a Prostate Biopsy Cohort With PSA Level of 4-10 ng/mL. [PDF]

Prostate
Furumido J, Nonoyama S, Hoshi C, Aizawa S, Ozaki N, Morita T, Yamashita A, Tsunemi I, Kato R, Hori K, Shimoda N.   +10 more
europepmc   +1 more source

Proteolytic Activation of the Epithelial Sodium Channel (ENaC): Its Mechanisms and Implications. [PDF]

Int J Mol Sci, 2023
Aufy M, Hussein AM, Stojanovic T, Studenik CR, Kotob MH.   +4 more
europepmc   +1 more source