Results 111 to 120 of about 88,456 (270)

How to treat addicted patient with concomitant psychiatric diagnosis?

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
Alcohol use disorders often co-occur with affective disorders, anxiety disorders and schizophrenia. The presence of dual diagnosis worsens the prognosis in patients.
A. Y. Egorov, F. Sh. Shagiahmetov
doaj  

Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors [PDF]

open access: yes, 2017
Cocaine addiction is a widespread psychiatric condition still waiting for approved efficacious medications. Previous studies suggested that simultaneous activation of nociceptin opioid (NOP) and mu opioid (MOP) receptors could be a successful strategy to
Cannella, Nazzareno   +3 more
core   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

Central nicotine induces browning through hypothalamic κ opioid receptor

open access: yesNature Communications, 2019
Nicotine reduces food intake and increases energy expenditure in brown adipose tissue. Here the authors show that nicotine also induces white adipose tissue browning via central kappa opioid receptor action.
Patricia Seoane-Collazo   +21 more
doaj   +1 more source

Diuretic Activity of a Novel Peripherally-Restricted Orally-Active Kappa Opioid Receptor Agonist

open access: yesMedical Sciences, 2019
Kappa-opioid agonists (KOAs) enhance cardiac performance, as well as reduce infarct size and prevent deleterious cardiac remodeling following myocardial infarction.
Tyler C. Beck   +3 more
doaj   +1 more source

The biopsychology of maternal behavior in nonhuman mammals [PDF]

open access: yes, 1990
The term “maternal behavior,” when applied to nonhuman mammals, includes the behaviors exhibited in preparation for the arrival of newborn, in the care and protection of the newly arrived young, and in the weaning of those young, and represents a complex
Kristal, Dr. Mark B.
core  

A guide to chemokines and their receptors [PDF]

open access: yes, 2018
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that signal through cell surface G‐protein coupled heptahelical chemokine receptors.
Braun A   +11 more
core   +1 more source

Determining Pharmacological Selectivity of the Kappa Opioid Receptor Antagonist LY2456302 Using Pupillometry as a Translational Biomarker in Rat and Human

open access: yesInternational Journal of Neuropsychopharmacology, 2015
Background: Selective kappa opioid receptor antagonism is a promising experimental strategy for the treatment of depression. The kappa opioid receptor antagonist, LY2456302, exhibits ~30-fold higher affinity for kappa opioid receptors over mu opioid ...
L. Rorick‐Kehn   +15 more
semanticscholar   +1 more source

Evaluation of buprenorphine as optimisation of postoperative analgesia in feral cats undergoing ovariohysterectomy under field conditions

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives The objective of this prospective, randomised, blinded, observational clinical study was to investigate the effect of subcutaneously administered buprenorphine on postoperative pain in female feral cats undergoing ovariohysterectomy as part of a trap‐neuter‐return programme.
V. Heitzmann   +3 more
wiley   +1 more source

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