Results 131 to 140 of about 88,456 (270)

Buprenorphine in Neonatal Abstinence Syndrome. [PDF]

, 2018
Infants exposed in utero to opioids will demonstrate a withdrawal syndrome known as neonatal abstinence syndrome (NAS). Buprenorphine is a long-acting opioid with therapeutic use in medication-assisted treatment of opioid dependency in adults and ...
Kraft, Walter K.
core   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Dynorphin-dependent reduction of excitability and attenuation of inhibitory afferents of NPS neurons in the pericoerulear region of mice

Frontiers in Cellular Neuroscience, 2016
The Neuropeptide S system, consisting of the 20-amino acid peptide neuropeptide S (NPS) and its G-protein coupled receptor (NPSR), modulates arousal, wakefulness, anxiety, and fear-extinction in mice.
Kay eJuengling, Peter eBlaesse, Lena eGoedecke, Hans-Christian ePape   +3 more
doaj   +1 more source

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

Journal of Internal Medicine, Volume 299, Issue 2, Page 196-215, February 2026.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego, Laura Gragnani, Marcella Visentini, Riccardo Bomben, Luca Arcaini, Clodoveo Ferri, Valter Gattei, Cesare Mazzaro   +7 more
wiley   +1 more source

The Differential Effects of a Selective Kappa-Opioid Receptor Agonist, U50488, in Guinea Pig Heart Tissues [PDF]

, 2015
Chi‐Feng Hung, Hsin‐Ju Li, Hsun-Hao Chang, Gon‐Ann Lee, Ming‐Jai Su   +4 more
openalex   +1 more source

Table4_Repeated Ethanol Exposure Alters DNA Methylation Status and Dynorphin/Kappa-Opioid Receptor Expression in Nucleus Accumbens of Alcohol-Preferring AA Rats.docx

, 2021
Kerly Niinep (11749988), Kaili Anier (11749991), Tony Eteläinen (11749994), Petteri Piepponen (9950699), Anti Kalda (11749997)   +4 more
openalex   +2 more sources

Adverse Effects of Opioid Dependency on Central and Peripheral Aspects of the Neuromuscular System

, 2019
Prevalence of chronic pain and health care costs have caused an escalation of opioid dependency. The current national crisis involving opioid dependency and drug overdose are growing problems that need to be addressed.
Yang, Cindy
core  

Nalfurafine hydrochloride to treat pruritus: a review

Clinical, Cosmetic and Investigational Dermatology, 2015
Shigeki InuiDepartment of Regenerative Dermatology, Osaka University Graduate School of Medicine, Osaka, JapanAbstract: Uremic pruritus has a great negative influence on quality of life in hemodialysis (HD) patients and, importantly, negatively affects ...
Inui S
doaj  

Opioid Receptors Gene Polymorphism and Heroin Dependence in Iran

Basic and Clinical Neuroscience, 2018
Introduction: Genes often have multiple polymorphisms that interact with each other and the environment in different individuals. Variability in the opioid receptors can influence opiate withdrawal and dependence.
Sara Soleimani Asl, Amir Roointan, Hugo Bergen, Shayan Amiri, Parastoo Mardani, Niloufar Ashtari, Ronak Shabani, Mehdi Mehdizadeh   +7 more
doaj  

Mapping Kappa Opioid Receptor Binding in Titi Monkeys with [C]GR103545 PET

Molecular Imaging
Purpose The kappa opioid receptor (KOR) plays a pivotal role in stress- and anxiety-related behaviors, with growing evidence linking it to stress induced by social isolation and separation.
Alita Jesal D Almeida BEng, Brad A. Hobson PhD, Logan E. Savidge PhD, Claudia Manca BS, John P. Paulus BS, Karen L. Bales PhD, Abhijit J. Chaudhari PhD   +6 more
doaj   +1 more source