Results 1 to 10 of about 6,232 (184)
A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies [PDF]
eLife, 2021 The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex mechanically couples cytoskeletal and nuclear components across the nuclear envelope to fulfil a myriad of cellular functions, including nuclear shape and positioning, hearing, and meiotic ...
Manickam Gurusaran, Owen Richard Davies
doaj +5 more sources
Nucleus, 2019 The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along with specialized ...
Hardeep Gumber +2 more
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KASH training models: increasing levels of commitment and organizational effectiveness
Business: Theory and Practice, 2023 The purpose of this article is to propose a strategic evaluation framework based on KASH training models, applicable in the first instance to SMEs in the clothing manufacturing sector in Bogota (Colombia), which in turn allows the possibility of ...
Diego Rafael Roberto Cabrera-Moya +2 more
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The KASH-containing isoform of Nesprin1 giant associates with ciliary rootlets of ependymal cells
Neurobiology of Disease, 2018 Biallelic nonsense mutations of SYNE1 underlie a variable array of cerebellar and non-cerebellar pathologies of unknown molecular etiology. SYNE1 encodes multiple isoforms of Nesprin1 that associate with the nuclear envelope, with large cerebellar ...
Moe Mahjoub, Didier Hodzic
exaly +3 more sources
Frontiers in Plant Science, 2020 Abscisic acid (ABA) induces stomatal closure by utilizing complex signaling mechanisms, allowing for sessile plants to respond rapidly to ever-changing environmental conditions.
Alecia Biel, Iris Meier, Morgan Moser
exaly +3 more sources
eLife, 2021 KASH proteins in the outer nuclear membrane comprise the cytoplasmic half of linker of nucleoskeleton and cytoskeleton (LINC) complexes that connect nuclei to the cytoskeleton.
Hongyan Hao +6 more
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Frontiers in Cell and Developmental Biology, 2023 The LINC complex, consisting of interacting SUN and KASH proteins, mechanically couples nuclear contents to the cytoskeleton. In meiosis, the LINC complex transmits microtubule-generated forces to chromosome ends, driving the rapid chromosome movements ...
Manickam Gurusaran +3 more
doaj +1 more source
Differential incorporation of SUN-domain proteins into LINC complexes is coupled to gene expression. [PDF]
PLoS ONE, 2018 LInkers of Nucleoskeleton and Cytoskeleton (LINC) complexes, composed of SUN and KASH-domain proteins, span the nuclear envelope and physically connect the nuclear interior to cytoskeletal elements.
Christopher K May, Christopher W Carroll
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Biomedicines, 2022 Kasugamycin (KSM), an aminoglycoside antibiotic, is composed of three chemical moieties: D-chiro-inositol, kasugamine and glycine imine. Despite being discovered more than 50 years ago, the biosynthetic pathway of KSM remains an unresolved puzzle.
Rajesh Rattinam +9 more
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Frontiers in Plant Science, 2022 The linker of nucleoskeleton and cytoskeleton (LINC) complex is a protein complex spanning the inner and outer membranes of the nuclear envelope. Outer nuclear membrane KASH proteins interact in the nuclear envelope lumen with inner nuclear membrane SUN ...
Alecia Biel +6 more
doaj +1 more source