Results 21 to 30 of about 6,232 (184)

Disulfide bond in SUN2 regulates dynamic remodeling of LINC complexes at the nuclear envelope

open access: yesLife Science Alliance, 2023
The LINC complex tethers the cell nucleus to the cytoskeleton to regulate mechanical forces during cell migration, differentiation, and various diseases.
Rahul Sharma, Martin W Hetzer
doaj   +1 more source

Drosophila Nesprin-1 Isoforms Differentially Contribute to Muscle Function

open access: yesCells, 2021
Nesprin-1 is a large scaffold protein connecting nuclei to the actin cytoskeleton via its KASH and Calponin Homology domains, respectively. Nesprin-1 disconnection from nuclei results in altered muscle function and myonuclei mispositioning.
Alexandre Rey   +3 more
doaj   +1 more source

Chain reaction: LINC complexes and nuclear positioning [version 1; referees: 3 approved]

open access: yesF1000Research, 2019
Nuclear positioning plays an essential role in defining cell architecture and behaviour in both development and disease, and nuclear location frequently adjusts according to internal and external cues.
Brian Burke
doaj   +1 more source

The N-terminal region of Jaw1 has a role to inhibit the formation of organized smooth endoplasmic reticulum as an intrinsically disordered region

open access: yesScientific Reports, 2021
Jaw1/LRMP is a type II integral membrane protein that is localized at the endoplasmic reticulum (ER) and outer nuclear membrane. We previously reported that a function of Jaw1 is to maintain the nuclear shape as a KASH protein via its carboxyl terminal ...
Takuma Kozono   +8 more
doaj   +1 more source

The city of Kash in Transoxiana, a study of its economic and cultural ‎conditions (55 AH/674 AD - 653 AH/1255 AD)‎ [PDF]

open access: yesمجلة جامعة الأنبار للعلوم الإنسانية
Aims: The research aims to study the city of Kash and identifies its political and cultural conditions under  the Arab-Islamic rule. The study also aimed to listing the most important Arab-Islamic campaigns that contributed to the conquest of the ...
Alaa Mutar Taieh
doaj   +1 more source

Mammalian sperm head formation involves different polarization of two novel LINC complexes. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: LINC complexes are nuclear envelope bridging protein structures formed by interaction of SUN and KASH proteins. They physically connect the nucleus with the peripheral cytoskeleton and are critically involved in a variety of dynamic processes,
Eva Göb   +3 more
doaj   +1 more source

Finding the missing KASH [PDF]

open access: yes, 2012
Poster Division: Biological Sciences: 2nd Place (The Ohio State University Edward F. Hayes Graduate Research Forum)The nucleus holds and protects the genetic information of a cell.
Zhou, Xiao
core   +1 more source

Annex KASH framework proposal

open access: yes, 2022
Documento anexo titulado "Anexo cuestionario para la evaluación de resultados de un modelo de entrenamiento KASH" disponible para aprovechamiento en formato PDF.#KASHDocument annex titled, "Annex questionnaire to evaluate results in a KASH model of ...
Cabrera Moya, Diego Rafael Roberto
core   +1 more source

Mps2 links Csm4 and Mps3 to form a telomere-associated LINC complex in budding yeast

open access: yesLife Science Alliance, 2020
The canonical LINC complex is composed of two different transmembrane proteins; this work reveals the heterotrimeric composition of the telomere-associated LINC complex in budding yeast. The linker of the nucleoskeleton and cytoskeleton (LINC) complex is
Jinbo Fan   +3 more
doaj   +1 more source

A Nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Nuclear positioning is important for the functionality of many cell types and is mediated by interactions of cytoskeletal elements and nucleoskeleton proteins.
Shahar Taiber   +12 more
doaj   +1 more source

Home - About - Disclaimer - Privacy